HitPredict

Interactor 1: HAS1 (Q03532)
ATP-dependent RNA helicase HAS1 (EC 3.6.4.13) (Helicase associated with SET1 protein 1)
Gene: HAS1

Interactor 2: IF6 (Q12522)
Eukaryotic translation initiation factor 6 (eIF-6)
Gene: TIF6

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.84	0.60	0.714

Property	Details
Experiments	11805826, 31511893, 16429126, 16095611, 37968396
Identification Methods	tandem affinity purification, affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000463 - maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) GO:0005730 - nucleolus GO:0006364 - rRNA processing GO:0030687 - preribosome, large subunit precursor GO:0042273 - ribosomal large subunit biogenesis
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 505 Sc			1 245
+	Hs
		880972 DDX55_HUMAN (43-486): 6.51e-172: 499: 37.45		IF6_HUMAN (1-245): 3.67e-144: 404: 72.25
+	Hs
		881026 DDX31_HUMAN (9-505): 3.72e-82: 274: 32.37		IF6_HUMAN (1-245): 3.67e-144: 404: 72.25
+	Sc
		699753 DRS1_YEAST (26-394): 3.8e-72: 245: 38.32		IF6_YEAST (1-245): 3.82e-140: 394: 100.00
+	Sc
		638908 SPB4_YEAST (56-488): 1.9e-61: 213: 33.41		IF6_YEAST (1-245): 3.82e-140: 394: 100.00