HitPredict - High confidence protein-protein interactions

Interactor 1: ACTA (P62737)
Actin, aortic smooth muscle (EC 3.6.4.-) (Alpha-actin-2) [Cleaved into: Actin, aortic smooth muscle, intermediate form]
Gene: Acta2

Interactor 2: ACTA (P62737)
Actin, aortic smooth muscle (EC 3.6.4.-) (Alpha-actin-2) [Cleaved into: Actin, aortic smooth muscle, intermediate form]
Gene: Acta2

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	29199018
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Actin~Actin
Common GO terms	GO:0001725 - stress fiber GO:0005524 - ATP binding GO:0005604 - basement membrane GO:0005737 - cytoplasm GO:0005856 - cytoskeleton and 21 others more... GO:0008217 - regulation of blood pressure GO:0009615 - response to virus GO:0010628 - positive regulation of gene expression GO:0014829 - vascular associated smooth muscle contraction GO:0015629 - actin cytoskeleton GO:0016787 - hydrolase activity GO:0019901 - protein kinase binding GO:0030027 - lamellipodium GO:0030175 - filopodium GO:0030485 - smooth muscle contractile fiber GO:0031514 - motile cilium GO:0032991 - protein-containing complex GO:0044297 - cell body GO:0061870 - positive regulation of hepatic stellate cell migration GO:0061874 - positive regulation of hepatic stellate cell contraction GO:0070374 - positive regulation of ERK1 and ERK2 cascade GO:0071560 - cellular response to transforming growth factor beta stimulus GO:0072051 - juxtaglomerular apparatus development GO:0072144 - glomerular mesangial cell development GO:0090131 - mesenchyme migration GO:2000491 - positive regulation of hepatic stellate cell activation
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1	377
Mm

1	377

Service provided by Combinatics, Japan

Last updated: 11Aug2025