HitPredict

Interactor 1: H4 (P62805)
Histone H4
Gene: H4C1

Interactor 2: HELLS (Q9NRZ9)
Lymphoid-specific helicase (EC 3.6.4.-) (Proliferation-associated SNF2-like protein) (SWI/SNF2-related matrix-associated actin-dependent regulator of chromatin subfamily A member 6)
Gene: HELLS

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	30804502
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	CENP-T_C~SNF2-rel_dom
Common GO terms	GO:0005634 - nucleus
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 103 Hs			1 838
+	Hs
		980464 H4_HUMAN (1-103): 1.39e-48: 151: 100.00		CHD7_HUMAN (22-836): 0: 660: 26.63
+	Hs
		979570 H4_HUMAN (1-103): 1.39e-48: 151: 100.00		CHD3_HUMAN (50-828): 0: 653: 24.79
+	Hs
		980365 H4_HUMAN (1-103): 1.39e-48: 151: 100.00		CHD8_HUMAN (2-836): 0: 638: 26.59
+	Hs
		979665 H4_HUMAN (1-103): 1.39e-48: 151: 100.00		CHD4_HUMAN (51-828): 0: 631: 25.27
+	Hs
		980029 H4_HUMAN (1-103): 1.39e-48: 151: 100.00		CHD6_HUMAN (7-836): 0: 628: 26.09
+	Hs
		979752 H4_HUMAN (1-103): 1.39e-48: 151: 100.00		CHD9_HUMAN (3-836): 0: 618: 26.25
+	Hs
		243587 H4_HUMAN (1-103): 1.39e-48: 151: 100.00		SMCA5_HUMAN (75-833): 0: 613: 30.63
+	Hs
		160171 H4_HUMAN (1-103): 1.39e-48: 151: 100.00		CHD2_HUMAN (5-830): 0: 598: 27.25
+	Sc
		382175 H4_YEAST (18-103): 6.16e-41: 132: 90.70		IRC5_YEAST (87-804): 0: 609: 38.03
+	Hs
		903303 H4_HUMAN (1-103): 1.39e-48: 151: 100.00		SMCA4_HUMAN (8-838): 0: 590: 22.96
+	Dm
		1014774 H4_DROME (1-103): 4.53e-48: 150: 99.03		ISWI_DROME (101-833): 0: 590: 30.07
+	Sp
		152971 H4_SCHPO (18-103): 4.89e-42: 135: 89.54		HRP3_SCHPO (55-833): 0: 597: 29.51
+	Sc
		381974 H4_YEAST (18-103): 6.16e-41: 132: 90.70		CHD1_YEAST (44-831): 0: 591: 28.91
+	Sc
		382398 H4_YEAST (18-103): 6.16e-41: 132: 90.70		ISW2_YEAST (213-805): 1.24e-126: 409: 41.21
+	Sc
		382048 H4_YEAST (18-103): 6.16e-41: 132: 90.70		ISW1_YEAST (212-772): 2e-120: 392: 41.95
+	Hs
		979924 H4_HUMAN (1-103): 1.39e-48: 151: 100.00		CHD1L_HUMAN (218-755): 1.81e-105: 347: 40.30
+	Sc
		381871 H4_YEAST (18-103): 6.16e-41: 132: 90.70		SNF2_YEAST (213-830): 4.31e-102: 349: 35.92
+	Sp
		206383 H4_SCHPO (18-103): 4.89e-42: 135: 89.54		FFT3_SCHPO (226-743): 3.06e-77: 271: 33.96
+	Sc
		381939 H4_YEAST (18-103): 6.16e-41: 132: 90.70		BTAF1_YEAST (211-826): 4.4e-70: 254: 30.83