HitPredict

Interactor 1: NCBP1 (Q09161)
Nuclear cap-binding protein subunit 1 (80 kDa nuclear cap-binding protein) (CBP80) (NCBP 80 kDa subunit)
Gene: NCBP1

Interactor 2: DDX21 (Q9NR30)
Nucleolar RNA helicase 2 (EC 3.6.4.13) (DEAD box protein 21) (Gu-alpha) (Nucleolar RNA helicase Gu) (Nucleolar RNA helicase II) (RH II/Gu)
Gene: DDX21

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	1.00	0.776

Property	Details
Experiments	35271311, 32960270
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	DEAD~MIF4G, Helicase_C~MIF4G
Common GO terms	GO:0003723 - RNA binding GO:0003729 - mRNA binding GO:0005654 - nucleoplasm GO:0005739 - mitochondrion GO:0005829 - cytosol and 1 others more... GO:0051607 - defense response to virus
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 790 Hs			1 783
+	Hs
		998141 NCBP1_HUMAN (1-790): 0: 1180: 100.00		DDX17_HUMAN (122-628): 1.38e-136: 423: 24.46
+	Hs
		134000 NCBP1_HUMAN (1-790): 0: 1180: 100.00		DDX3X_HUMAN (5-575): 3.96e-137: 422: 23.55
+	Hs
		571416 NCBP1_HUMAN (1-790): 0: 1180: 100.00		DDX5_HUMAN (92-620): 4.08e-135: 415: 24.81
+	Hs
		757586 NCBP1_HUMAN (1-790): 0: 1180: 100.00		IF4A3_HUMAN (169-554): 5.06e-54: 194: 32.23
+	Sc
		415939 NCBP1_YEAST (3-693): 2.4e-99: 329: 17.53		DED1_YEAST (196-541): 2.98e-56: 205: 37.98