HitPredict

Interactor 1: EP300 (Q09472)
Histone acetyltransferase p300 (p300 HAT) (EC 2.3.1.48) (E1A-associated protein p300) (Histone butyryltransferase p300) (EC 2.3.1.-) (Histone crotonyltransferase p300) (EC 2.3.1.-) (Protein 2-hydroxyisobutyryltransferase p300) (EC 2.3.1.-) (Protein lactyltransferas p300) (EC 2.3.1.-) (Protein propionyltransferase p300) (EC 2.3.1.-)
Gene: EP300

Interactor 2: SNW1 (Q13573)
SNW domain-containing protein 1 (Nuclear protein SkiP) (Nuclear receptor coactivator NCoA-62) (Ski-interacting protein)
Gene: SNW1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.61	0.60	0.608

The method score is based on:

Property	Details
Experiments	33742100, 14985122
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0003713 - transcription coactivator activity GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0016922 - nuclear receptor binding and 5 others more... GO:0030511 - positive regulation of transforming growth factor beta receptor signaling pathway GO:0042771 - intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator GO:0043923 - positive regulation by host of viral transcription GO:0045944 - positive regulation of transcription by RNA polymerase II GO:0050681 - nuclear androgen receptor binding
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1	2414
Hs

1	536

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024