HitPredict

Interactor 1: EP300 (Q09472)
Histone acetyltransferase p300 (p300 HAT) (EC 2.3.1.48) (E1A-associated protein p300) (Histone butyryltransferase p300) (EC 2.3.1.-) (Histone crotonyltransferase p300) (EC 2.3.1.-) (Protein 2-hydroxyisobutyryltransferase p300) (EC 2.3.1.-) (Protein lactyltransferas p300) (EC 2.3.1.-) (Protein propionyltransferase p300) (EC 2.3.1.-)
Gene: EP300

Interactor 2: SMCE1 (Q969G3)
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 (BRG1-associated factor 57) (BAF57)
Gene: SMARCE1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	30110629
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0003682 - chromatin binding GO:0003713 - transcription coactivator activity GO:0005634 - nucleus GO:0005654 - nucleoplasm and 1 others more... GO:0016922 - nuclear receptor binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2414 Hs			1 411
+	Hs
		567685 EP300_HUMAN (1-2414): 0: 1113: 100.00		UBF1_HUMAN (55-380): 1.54e-40: 155: 14.99
+	Hs
		996631 EP300_HUMAN (1-2414): 0: 1113: 100.00		SSRP1_HUMAN (61-135): 1.2e-21: 99.3: 25.33
+	Mm
		57642 EP300_MOUSE (1-2414): 0: 1090: 93.01		A2AWT7_MOUSE (47-402): 2.66e-09: 61.3: 10.39
+	Dm
		116021 M9PH39_DROME (430-2323): 0: 769: 36.52		Q9VUD3_DROME (18-186): 1.25e-34: 136: 14.79
+	Hs
		1281264 TRI33_HUMAN (604-1201): 1.37e-44: 180: 14.50		SMCE1_HUMAN (1-411): 6.03e-79: 251: 100.00
+	Hs
		631540 BRD2_HUMAN (1035-1159): 9.57e-30: 131: 31.20		SMCE1_HUMAN (1-411): 6.03e-79: 251: 100.00
+	Hs
		1067084 BRD3_HUMAN (1055-1159): 9.06e-30: 130: 30.48		SMCE1_HUMAN (1-411): 6.03e-79: 251: 100.00
+	Hs
		1332336 NCOA3_HUMAN (1849-2386): 7.64e-52: 204: 21.89		SOX17_HUMAN (2-168): 1.77e-33: 131: 17.26
+	Hs
		1281258 CHD7_HUMAN (69-452): 4.51e-13: 77.9: 12.02		SMCE1_HUMAN (1-411): 6.03e-79: 251: 100.00
+	Hs
		1332331 TRI33_HUMAN (604-1201): 1.37e-44: 180: 14.50		SOX17_HUMAN (2-168): 1.77e-33: 131: 17.26
+	Hs
		567642 BRD2_HUMAN (1035-1159): 9.57e-30: 131: 31.20		UBF1_HUMAN (55-380): 1.54e-40: 155: 14.99
+	Hs
		567703 BRD3_HUMAN (1055-1159): 9.06e-30: 130: 30.48		UBF1_HUMAN (55-380): 1.54e-40: 155: 14.99
+	Hs
		996921 BRWD1_HUMAN (1007-1168): 2.52e-44: 180: 32.93		SSRP1_HUMAN (61-135): 1.2e-21: 99.3: 25.33
+	Hs
		996961 TRI33_HUMAN (604-1201): 1.37e-44: 180: 14.50		SSRP1_HUMAN (61-135): 1.2e-21: 99.3: 25.33
+	Hs
		1067153 BRD3_HUMAN (1055-1159): 9.06e-30: 130: 30.48		HM20A_HUMAN (3-308): 1.64e-39: 146: 16.08
+	Hs
		958916 BRD3_HUMAN (1055-1159): 9.06e-30: 130: 30.48		TFAM_HUMAN (64-259): 2.52e-29: 116: 19.19
+	Hs
		631411 BRD2_HUMAN (1035-1159): 9.57e-30: 131: 31.20		SSRP1_HUMAN (61-135): 1.2e-21: 99.3: 25.33
+	Hs
		996682 BRD3_HUMAN (1055-1159): 9.06e-30: 130: 30.48		SSRP1_HUMAN (61-135): 1.2e-21: 99.3: 25.33
+	Hs
		959038 BRD8_HUMAN (965-1183): 9.91e-16: 86: 19.18		TFAM_HUMAN (64-259): 2.52e-29: 116: 19.19
+	Hs
		175778 BRD3_HUMAN (1055-1159): 9.06e-30: 130: 30.48		HMGB3_HUMAN (62-135): 6.4e-13: 69.3: 25.68