Protein: ES8L2
Epidermal growth factor receptor kinase substrate 8-like protein 2 (EPS8-like protein 2) (Epidermal growth factor receptor pathway substrate 8-related protein 2) (EPS8-related protein 2)

Gene: ES8L2, EPS8L2
Organism: Homo sapiens
Interactions: 54
UniProt ID: Q9H6S3

Gene Ontology (top 5):
GO:0003779 - actin binding
GO:0005813 - centrosome
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0007266 - Rho protein signal transduction

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

228706

PRKN
E3 ubiquitin-protein ligase parkin

2

9

High-throughput

0.754

High

1144627

TENS2
Tensin-2

2

18

High-throughput

0.743

High

983670

FAK1
Focal adhesion kinase 1

1

20

High-throughput

0.656

High

427122

CATD
Cathepsin D

1

0

High-throughput

0.630

High

299130

SASH1
SAM and SH3 domain-containing protein 1

1

1

Small-scale

0.621

High

992495

SOS1
Son of sevenless homolog 1

1

20

Small-scale

0.618

High

1224645

ABI1
Abl interactor 1

1

20

Small-scale

0.618

High

231716

KIF1B
Kinesin-like protein KIF1B

1

10

High-throughput

0.594

High

1251917

RIN3
Ras and Rab interactor 3

2

17

High-throughput

0.576

High

1153386

PKHA7
Pleckstrin homology domain-containing family A member 7

1

20

High-throughput

0.575

High

258198

DNJB6
DnaJ homolog subfamily B member 6

1

3

High-throughput

0.536

High

504766

HSP7C
Heat shock cognate 71 kDa protein

1

7

High-throughput

0.536

High

686745

CCR1
C-C chemokine receptor type 1

1

8

High-throughput

0.536

High

882809

STX17
Syntaxin-17

1

2

High-throughput

0.536

High

1239234

FNDC5
Fibronectin type III domain-containing protein 5

1

1

High-throughput

0.536

High

1240993

SERB1
SERPINE1 mRNA-binding protein 1

1

1

High-throughput

0.536

High

1269154

PGTA
Geranylgeranyl transferase type-2 subunit alpha

1

8

High-throughput

0.536

High

1315597

SRRT
Serrate RNA effector molecule homolog

1

1

High-throughput

0.536

High

1332474

MBNL1
Muscleblind-like protein 1

1

1

High-throughput

0.536

High

1332475

FGOP2
FGFR1 oncogene partner 2

1

1

High-throughput

0.536

High

1332477

WASF3
Actin-binding protein WASF3

1

19

High-throughput

0.536

High

281891

WFS1
Wolframin

1

3

High-throughput

0.515

High

422291

NFL
Neurofilament light polypeptide

1

7

High-throughput

0.515

High

660707

GRN
Progranulin

1

1

High-throughput

0.515

High

1191576

SPRE1
Sprouty-related, EVH1 domain-containing protein 1

1

10

High-throughput

0.515

High

565974

AATC
Aspartate aminotransferase, cytoplasmic

1

0

High-throughput

0.513

High

1288695

RM38
Large ribosomal subunit protein mL38

1

0

High-throughput

0.513

High

1332478

NTNG1
Netrin-G1

1

0

High-throughput

0.513

High

395773

A4
Amyloid-beta precursor protein

1

5

High-throughput

0.501

High

1130594

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

8

High-throughput

0.501

High

1282042

TRI63
E3 ubiquitin-protein ligase TRIM63

1

19

High-throughput

0.494

High

1317512

TRI55
Tripartite motif-containing protein 55

1

20

High-throughput

0.494

High

47712

S12A8
Solute carrier family 12 member 8

1

7

High-throughput

0.489

High

303722

OR2A4
Olfactory receptor 2A4

1

2

High-throughput

0.489

High

1039853

SNW1
SNW domain-containing protein 1

1

1

High-throughput

0.489

High

1303750

CDC5L
Cell division cycle 5-like protein

1

2

High-throughput

0.489

High

1332479

SSUH2
Protein SSUH2 homolog

1

1

High-throughput

0.489

High

919519

RL23
Large ribosomal subunit protein uL14

1

2

High-throughput

0.481

High

163281

XPO1
Exportin-1

1

2

High-throughput

0.479

High

210282

PRC1
Protein regulator of cytokinesis 1

1

9

High-throughput

0.479

High

430722

CD3E
T-cell surface glycoprotein CD3 epsilon chain

1

6

Small-scale

0.479

High

522195

CADH1
Cadherin-1

1

11

High-throughput

0.479

High

930007

ACTG
Actin, cytoplasmic 2

1

7

Small-scale

0.479

High

1035592

SMAD4
Mothers against decapentaplegic homolog 4

1

3

High-throughput

0.479

High

1281392

FBXW7
F-box/WD repeat-containing protein 7

1

1

High-throughput

0.479

High

1287381

OPTN
Optineurin

1

20

High-throughput

0.479

High

1332476

ZRAN1
Ubiquitin thioesterase ZRANB1

1

6

High-throughput

0.479

High

103844

G5E9A7
DM1 locus, WD repeat containing

1

9

High-throughput

0.470

High

1085349

FSCN1
Fascin

1

0

High-throughput

0.458

High

529726

CFTR
Cystic fibrosis transmembrane conductance regulator

1

6

High-throughput

0.445

High

903520

WDR5
WD repeat-containing protein 5

1

4

High-throughput

0.437

High

1103127

ASTE1
Protein asteroid homolog 1

2

0

High-throughput

0.328

High

1295795

CH076
Uncharacterized protein C8orf76

1

0

High-throughput

0.279

Low

1327888

PUS7L
Pseudouridylate synthase PUS7L

1

0

High-throughput

0.279

Low


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Last updated: 15 Jul 2024