Protein: CD6
T-cell differentiation antigen CD6 (T12) (TP120) (CD antigen CD6) [Cleaved into: Soluble CD6]

Gene: CD6
Organism: Homo sapiens
Interactions: 159
UniProt ID: P30203

Gene Ontology (top 5):
GO:0001530 - lipopolysaccharide binding
GO:0001771 - immunological synapse formation
GO:0001772 - immunological synapse
GO:0001934 - positive regulation of protein phosphorylation
GO:0002250 - adaptive immune response

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

672637

CD6
T-cell differentiation antigen CD6

1

6

Small-scale

0.716

High

672665

CD166
CD166 antigen

4

2

Small-scale

0.708

High

410610

CD5
T-cell surface glycoprotein CD5

1

6

Small-scale

0.647

High

449203

LEG1
Galectin-1

1

5

Small-scale

0.536

High

572292

LEG3
Galectin-3

1

5

Small-scale

0.536

High

160400

AURKA
Aurora kinase A

1

1

High-throughput

0.536

High

259265

UBP12
Ubiquitin carboxyl-terminal hydrolase 12

1

1

High-throughput

0.536

High

640213

PTN3
Tyrosine-protein phosphatase non-receptor type 3

1

5

High-throughput

0.536

High

669131

TYK2
Non-receptor tyrosine-protein kinase TYK2

1

6

High-throughput

0.536

High

672642

GRK6
G protein-coupled receptor kinase 6

1

1

High-throughput

0.536

High

672644

PI42A
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha

1

3

High-throughput

0.536

High

672647

FXR1
RNA-binding protein FXR1

1

7

High-throughput

0.536

High

672648

FXR2
RNA-binding protein FXR2

1

7

High-throughput

0.536

High

672651

CSK21
Casein kinase II subunit alpha

1

5

High-throughput

0.536

High

672652

PI42B
Phosphatidylinositol 5-phosphate 4-kinase type-2 beta

1

3

High-throughput

0.536

High

672659

FMR1
Fragile X messenger ribonucleoprotein 1

1

7

High-throughput

0.536

High

672663

MTMR1
Myotubularin-related protein 1

1

1

High-throughput

0.536

High

672674

PKHG4
Puratrophin-1

1

3

High-throughput

0.536

High

672679

TRI68
E3 ubiquitin-protein ligase TRIM68

1

1

High-throughput

0.536

High

672687

FRMD5
FERM domain-containing protein 5

1

8

High-throughput

0.536

High

672692

HOME1
Homer protein homolog 1

1

2

High-throughput

0.536

High

672701

VANG1
Vang-like protein 1

1

1

High-throughput

0.536

High

672702

PI42C
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma

1

3

High-throughput

0.536

High

672703

ARH40
Rho guanine nucleotide exchange factor 40

1

4

High-throughput

0.536

High

672706

SNX33
Sorting nexin-33

1

1

High-throughput

0.536

High

672707

RN138
E3 ubiquitin-protein ligase RNF138

1

6

High-throughput

0.536

High

672723

SNX18
Sorting nexin-18

1

1

High-throughput

0.536

High

672724

PI51A
Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha

1

3

High-throughput

0.536

High

672731

E41L1
Band 4.1-like protein 1

1

7

High-throughput

0.536

High

672736

E41L5
Band 4.1-like protein 5

1

8

High-throughput

0.536

High

672742

HOME2
Homer protein homolog 2

1

2

High-throughput

0.536

High

672752

VANG2
Vang-like protein 2

1

1

High-throughput

0.536

High

672758

E41L3
Band 4.1-like protein 3

1

7

High-throughput

0.536

High

672643

GLYG
Glycogenin-1

1

0

High-throughput

0.518

High

672638

ARRB2
Beta-arrestin-2

1

0

High-throughput

0.513

High

672653

SMAD3
Mothers against decapentaplegic homolog 3

1

0

High-throughput

0.513

High

672657

OCRL
Inositol polyphosphate 5-phosphatase OCRL

1

0

High-throughput

0.513

High

672662

PLD1
Phospholipase D1

1

0

High-throughput

0.513

High

672696

PLCD3
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3

1

0

High-throughput

0.513

High

672699

CAMKV
CaM kinase-like vesicle-associated protein

1

0

High-throughput

0.513

High

672715

TIFA
TRAF-interacting protein with FHA domain-containing protein A

1

0

High-throughput

0.513

High

672719

EXOC2
Exocyst complex component 2

1

0

High-throughput

0.513

High

672737

JPH1
Junctophilin-1

1

0

High-throughput

0.513

High

672741

LANC2
LanC-like protein 2

1

0

High-throughput

0.513

High

672749

DAXX
Death domain-associated protein 6

1

0

High-throughput

0.513

High

127460

RPOM
DNA-directed RNA polymerase, mitochondrial

1

1

High-throughput

0.489

High

253539

CAPON
Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein

1

1

High-throughput

0.489

High

254949

ZBED4
Zinc finger BED domain-containing protein 4

1

2

High-throughput

0.489

High

255539

OBSL1
Obscurin-like protein 1

1

4

High-throughput

0.489

High

267912

EED
Polycomb protein EED

1

2

High-throughput

0.489

High

299241

FARP2
FERM, ARHGEF and pleckstrin domain-containing protein 2

1

8

High-throughput

0.489

High

309446

MTMR5
Myotubularin-related protein 5

1

1

High-throughput

0.489

High

311484

SMC2
Structural maintenance of chromosomes protein 2

1

2

High-throughput

0.489

High

321973

ZMYM6
Zinc finger MYM-type protein 6

1

1

High-throughput

0.489

High

324745

M4K4
Mitogen-activated protein kinase kinase kinase kinase 4

1

4

High-throughput

0.489

High

563565

ZNF24
Zinc finger protein 24

1

1

High-throughput

0.489

High

567815

HXB9
Homeobox protein Hox-B9

1

2

High-throughput

0.489

High

579123

ATF1
Cyclic AMP-dependent transcription factor ATF-1

1

1

High-throughput

0.489

High

584556

ERCC3
General transcription and DNA repair factor IIH helicase/translocase subunit XPB

1

4

High-throughput

0.489

High

586580

CSK22
Casein kinase II subunit alpha'

1

4

High-throughput

0.489

High

658315

DPOD1
DNA polymerase delta catalytic subunit

1

1

High-throughput

0.489

High

672641

CNDD3
Condensin-2 complex subunit D3

1

1

High-throughput

0.489

High

672645

KC1E
Casein kinase I isoform epsilon

1

1

High-throughput

0.489

High

672650

RS26
Small ribosomal subunit protein eS26

1

1

High-throughput

0.489

High

672654

FOXK1
Forkhead box protein K1

1

3

High-throughput

0.489

High

672655

FOXK2
Forkhead box protein K2

1

3

High-throughput

0.489

High

672661

DHRS2
Dehydrogenase/reductase SDR family member 2, mitochondrial

1

1

High-throughput

0.489

High

672664

CUL4B
Cullin-4B

1

6

High-throughput

0.489

High

672669

RRP5
Protein RRP5 homolog

1

1

High-throughput

0.489

High

672671

WDR43
WD repeat-containing protein 43

1

1

High-throughput

0.489

High

672672

RASA2
Ras GTPase-activating protein 2

1

1

High-throughput

0.489

High

672675

CEP78
Centrosomal protein of 78 kDa

1

1

High-throughput

0.489

High

672676

ZMYM1
Zinc finger MYM-type protein 1

1

1

High-throughput

0.489

High

672681

RETST
All-trans-retinol 13,14-reductase

1

1

High-throughput

0.489

High

672682

FIGL1
Fidgetin-like protein 1

1

1

High-throughput

0.489

High

672684

PAXI1
PAX-interacting protein 1

1

1

High-throughput

0.489

High

672690

KI18B
Kinesin-like protein KIF18B

1

1

High-throughput

0.489

High

672691

DZIP1
Cilium assembly protein DZIP1

1

5

High-throughput

0.489

High

672693

WDR75
WD repeat-containing protein 75

1

2

High-throughput

0.489

High

672694

DZI1L
Cilium assembly protein DZIP1L

1

7

High-throughput

0.489

High

672695

LRC47
Leucine-rich repeat-containing protein 47

1

1

High-throughput

0.489

High

672697

SRBD1
S1 RNA-binding domain-containing protein 1

1

1

High-throughput

0.489

High

672700

KBTB8
Kelch repeat and BTB domain-containing protein 8

1

1

High-throughput

0.489

High

672708

HNRLL
Heterogeneous nuclear ribonucleoprotein L-like

1

2

High-throughput

0.489

High

672709

BBX
HMG box transcription factor BBX

1

3

High-throughput

0.489

High

672713

RAD50
DNA repair protein RAD50

1

5

High-throughput

0.489

High

672714

UTP4
U3 small nucleolar RNA-associated protein 4 homolog

1

1

High-throughput

0.489

High

672718

REXO5
RNA exonuclease 5

1

2

High-throughput

0.489

High

672720

AGAP3
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3

1

2

High-throughput

0.489

High

672721

LENG8
Leukocyte receptor cluster member 8

1

1

High-throughput

0.489

High

672727

GNB1L
Guanine nucleotide-binding protein subunit beta-like protein 1

1

1

High-throughput

0.489

High

672728

CRNL1
Crooked neck-like protein 1

1

1

High-throughput

0.489

High

672730

DDX47
Probable ATP-dependent RNA helicase DDX47

1

3

High-throughput

0.489

High

672734

ECT2
Protein ECT2

1

2

High-throughput

0.489

High

672738

MYNN
Myoneurin

1

1

High-throughput

0.489

High

672740

XPP1
Xaa-Pro aminopeptidase 1

1

1

High-throughput

0.489

High

672743

SMC4
Structural maintenance of chromosomes protein 4

1

3

High-throughput

0.489

High

672745

DDX56
Probable ATP-dependent RNA helicase DDX56

1

4

High-throughput

0.489

High

672746

UTP6
U3 small nucleolar RNA-associated protein 6 homolog

1

2

High-throughput

0.489

High

672750

FBW1B
F-box/WD repeat-containing protein 11

1

2

High-throughput

0.489

High

672751

TAOK2
Serine/threonine-protein kinase TAO2

1

2

High-throughput

0.489

High

672753

ZMYD8
MYND-type zinc finger-containing chromatin reader ZMYND8

1

2

High-throughput

0.489

High

672756

AGAP1
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1

1

1

High-throughput

0.489

High

672757

FBW1A
F-box/WD repeat-containing protein 1A

1

2

High-throughput

0.489

High

672761

FARP1
FERM, ARHGEF and pleckstrin domain-containing protein 1

1

7

High-throughput

0.489

High

132748

SDCB1
Syntenin-1

1

2

Small-scale

0.479

High

672660

LCP2
Lymphocyte cytosolic protein 2

1

1

High-throughput

0.457

High

72376

B3KW44
tRNA N(3)-methylcytidine methyltransferase

1

1

High-throughput

0.437

High

346027

MYC
Myc proto-oncogene protein

1

4

Small-scale

0.437

High

672733

METL8
tRNA N(3)-methylcytidine methyltransferase METTL8, mitochondrial

1

1

High-throughput

0.407

High

672667

NF2L1
Endoplasmic reticulum membrane sensor NFE2L1

1

0

High-throughput

0.282

High

51094

CBAR1
CBY1-interacting BAR domain-containing protein 1

1

0

High-throughput

0.279

Low

179559

RPA34
DNA-directed RNA polymerase I subunit RPA34

1

0

High-throughput

0.279

Low

203277

FIBP
Acidic fibroblast growth factor intracellular-binding protein

1

0

High-throughput

0.279

Low

246175

NBN
Nibrin

1

0

High-throughput

0.279

Low

314954

SGPL1
Sphingosine-1-phosphate lyase 1

1

0

High-throughput

0.279

Low

317078

RPA1
DNA-directed RNA polymerase I subunit RPA1

1

0

High-throughput

0.279

Low

625154

CDK2
Cyclin-dependent kinase 2

1

0

High-throughput

0.279

Low

672639

TF2H1
General transcription factor IIH subunit 1

1

0

High-throughput

0.279

Low

672640

BMI1
Polycomb complex protein BMI-1

1

0

High-throughput

0.279

Low

672646

MRE11
Double-strand break repair protein MRE11

1

0

High-throughput

0.279

Low

672649

SELB
Selenocysteine-specific elongation factor

1

0

High-throughput

0.279

Low

672656

AMPD2
AMP deaminase 2

1

0

High-throughput

0.279

Low

672658

SUH
Recombining binding protein suppressor of hairless

1

0

High-throughput

0.279

Low

672666

TF2H2
General transcription factor IIH subunit 2

1

0

High-throughput

0.279

Low

672668

RRP1B
Ribosomal RNA processing protein 1 homolog B

1

0

High-throughput

0.279

Low

672670

PSME4
Proteasome activator complex subunit 4

1

0

High-throughput

0.279

Low

672673

CTC1
CST complex subunit CTC1

1

0

High-throughput

0.279

Low

672677

DEP1A
DEP domain-containing protein 1A

1

0

High-throughput

0.279

Low

672678

AHDC1
Transcription factor Gibbin

1

0

High-throughput

0.279

Low

672680

CNDH2
Condensin-2 complex subunit H2

1

0

High-throughput

0.279

Low

672683

ZN852
Zinc finger protein 852

1

0

High-throughput

0.279

Low

672685

APTX
Aprataxin

1

0

High-throughput

0.279

Low

672686

TRM1L
TRMT1-like protein

1

0

High-throughput

0.279

Low

672688

CNDG2
Condensin-2 complex subunit G2

1

0

High-throughput

0.279

Low

672689

PTH
Peptidyl-tRNA hydrolase

1

0

High-throughput

0.279

Low

672698

TAC2N
Tandem C2 domains nuclear protein

1

0

High-throughput

0.279

Low

672704

TF3C2
General transcription factor 3C polypeptide 2

1

0

High-throughput

0.279

Low

672705

CCD12
Coiled-coil domain-containing protein 12

1

0

High-throughput

0.279

Low

672710

IP6K1
Inositol hexakisphosphate kinase 1

1

0

High-throughput

0.279

Low

672711

ZN592
Zinc finger protein 592

1

0

High-throughput

0.279

Low

672712

TF2H4
General transcription factor IIH subunit 4

1

0

High-throughput

0.279

Low

672716

MCRS1
Microspherule protein 1

1

0

High-throughput

0.279

Low

672717

CYFP2
Cytoplasmic FMR1-interacting protein 2

1

0

High-throughput

0.279

Low

672722

TEFM
Transcription elongation factor, mitochondrial

1

0

High-throughput

0.279

Low

672725

PDD2L
Programmed cell death protein 2-like

1

0

High-throughput

0.279

Low

672726

TR61B
tRNA

1

0

High-throughput

0.279

Low

672729

RPA49
DNA-directed RNA polymerase I subunit RPA49

1

0

High-throughput

0.279

Low

672732

STN1
CST complex subunit STN1

1

0

High-throughput

0.279

Low

672735

IPPK
Inositol-pentakisphosphate 2-kinase

1

0

High-throughput

0.279

Low

672739

PRD10
PR domain zinc finger protein 10

1

0

High-throughput

0.279

Low

672744

TBCC1
TBCC domain-containing protein 1

1

0

High-throughput

0.279

Low

672747

DIP2B
Disco-interacting protein 2 homolog B

1

0

High-throughput

0.279

Low

672748

IKBL1
NF-kappa-B inhibitor-like protein 1

1

0

High-throughput

0.279

Low

672754

ABT1
Activator of basal transcription 1

1

0

High-throughput

0.279

Low

672755

DUS12
Dual specificity protein phosphatase 12

1

0

High-throughput

0.279

Low

672759

CBY1
Protein chibby homolog 1

1

0

High-throughput

0.279

Low

672760

HBS1L
HBS1-like protein

1

0

High-throughput

0.279

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024