Interactor 1: Q5U0Y0 (Q5U0Y0)
Paired amphipathic helix protein Sin3a (Histone deacetylase complex subunit Sin3a) (Transcriptional corepressor Sin3a)
Gene: Sin3A
Interactor 2: HDAC1 (Q94517)
Histone deacetylase HDAC1 (HD) (EC 3.5.1.98)
Gene: HDAC1
Species: Drosophila melanogaster
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.84 | 1.00 | 0.920 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 22036573, 20566628, 10973955, 23177352, 38944040, unassigned4 |
| Identification Methods | affinity chromatography technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, experimental interaction detection |
| Interaction Type | physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Hist_deacetyl~Sin3_corepress, Hist_deacetyl~Sin3a_C |
| Common GO terms | GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0000785 - chromatin GO:0003714 - transcription corepressor activity GO:0005634 - nucleus GO:0005700 - polytene chromosome and 4 others more... |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
