Protein: RTEL1
Regulator of telomere elongation helicase 1 (EC 3.6.4.12) (Novel helicase-like)

Gene: RTEL1
Organism: Homo sapiens
Interactions: 85
UniProt ID: Q9NZ71

Gene Ontology (top 5):
GO:0000723 - telomere maintenance
GO:0000732 - DNA strand displacement
GO:0000781 - chromosome, telomeric region
GO:0003677 - DNA binding
GO:0003678 - DNA helicase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1303009

MMS19
MMS19 nucleotide excision repair protein homolog

5

4

Small-scale

0.706

High

1222610

SLX4
Structure-specific endonuclease subunit SLX4

3

2

Small-scale

0.669

High

899066

PSME3
Proteasome activator complex subunit 3

3

2

High-throughput

0.667

High

1042695

CUL3
Cullin-3

2

3

High-throughput

0.611

High

1203521

SKAP1
Src kinase-associated phosphoprotein 1

2

3

High-throughput

0.611

High

146414

ISLR
Immunoglobulin superfamily containing leucine-rich repeat protein

3

1

High-throughput

0.609

High

1263113

LIPH
Lipase member H

3

1

High-throughput

0.609

High

428473

TBB5
Tubulin beta chain

2

0

High-throughput

0.602

High

1348950

NGN3
Neurogenin-3

2

0

High-throughput

0.602

High

1069539

TEBP
Prostaglandin E synthase 3

2

1

High-throughput

0.601

High

728669

PPM1A
Protein phosphatase 1A

2

0

High-throughput

0.585

High

1310637

ZNG1A
Zinc-regulated GTPase metalloprotein activator 1A

2

0

High-throughput

0.585

High

1078261

EFNB3
Ephrin-B3

2

2

High-throughput

0.574

High

1239478

GALD1
Glutamine amidotransferase-like class 1 domain-containing protein 1

2

1

High-throughput

0.574

High

1348949

CIA2B
Cytosolic iron-sulfur assembly component 2B

2

5

Small-scale

0.571

High

132040

VMA5A
von Willebrand factor A domain-containing protein 5A

1

2

High-throughput

0.536

High

149930

RFXK
DNA-binding protein RFXANK

1

2

High-throughput

0.536

High

515960

PRPS2
Ribose-phosphate pyrophosphokinase 2

1

2

High-throughput

0.536

High

975750

LMNB2
Lamin-B2

1

2

High-throughput

0.536

High

986861

PSME1
Proteasome activator complex subunit 1

1

2

High-throughput

0.536

High

992717

LRP1
Prolow-density lipoprotein receptor-related protein 1

1

1

High-throughput

0.536

High

1152400

CNDH2
Condensin-2 complex subunit H2

1

1

High-throughput

0.536

High

1283600

TRI52
E3 ubiquitin-protein ligase TRIM52

1

1

High-throughput

0.536

High

1332125

CIA2A
Cytosolic iron-sulfur assembly component 2A

1

5

High-throughput

0.536

High

245754

B4GT2
Beta-1,4-galactosyltransferase 2

1

0

High-throughput

0.513

High

265435

KTNA1
Katanin p60 ATPase-containing subunit A1

1

0

High-throughput

0.513

High

525085

XRCC5
X-ray repair cross-complementing protein 5

1

0

High-throughput

0.513

High

557808

NCK1
SH2/SH3 adapter protein NCK1

1

0

High-throughput

0.513

High

729186

K22E
Keratin, type II cytoskeletal 2 epidermal

1

0

High-throughput

0.513

High

863805

LIMK1
LIM domain kinase 1

1

0

High-throughput

0.513

High

1284829

EFMT3
EEF1A lysine methyltransferase 3

1

0

High-throughput

0.513

High

1302602

INT14
Integrator complex subunit 14

1

0

High-throughput

0.513

High

1318406

UBXN6
UBX domain-containing protein 6

1

0

High-throughput

0.513

High

179272

COPT1
High affinity copper uptake protein 1

1

2

High-throughput

0.489

High

873762

SLUR1
Secreted Ly-6/uPAR-related protein 1

1

1

High-throughput

0.489

High

1234871

TTC9C
Tetratricopeptide repeat protein 9C

1

3

High-throughput

0.489

High

402555

JUN
Transcription factor Jun

1

1

High-throughput

0.479

High

553913

RFA2
Replication protein A 32 kDa subunit

1

2

High-throughput

0.479

High

652450

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

2

High-throughput

0.479

High

721632

RFA3
Replication protein A 14 kDa subunit

1

2

High-throughput

0.479

High

855827

VAV2
Guanine nucleotide exchange factor VAV2

1

1

High-throughput

0.479

High

988150

RAD51
DNA repair protein RAD51 homolog 1

1

3

High-throughput

0.479

High

1190881

EMSY
BRCA2-interacting transcriptional repressor EMSY

1

2

High-throughput

0.479

High

1224707

WDFY3
WD repeat and FYVE domain-containing protein 3

1

2

High-throughput

0.479

High

1289770

THA11
THAP domain-containing protein 11

1

1

High-throughput

0.479

High

1330867

Q9H4D1
Protein kinase

1

1

High-throughput

0.479

High

1343042

AT132
Polyamine-transporting ATPase 13A2

1

1

High-throughput

0.479

High

1348169

AATF
Protein AATF

1

1

High-throughput

0.479

High

1348945

NDUAD
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13

1

1

High-throughput

0.479

High

151224

DVL2
Segment polarity protein dishevelled homolog DVL-2

1

0

High-throughput

0.458

High

271205

UBP2
Ubiquitin carboxyl-terminal hydrolase 2

1

0

Small-scale

0.458

High

328977

TOP3B
DNA topoisomerase 3-beta-1

1

0

High-throughput

0.458

High

1146199

DCA15
DDB1- and CUL4-associated factor 15

1

0

High-throughput

0.458

High

1272218

XPF
DNA repair endonuclease XPF

1

0

Small-scale

0.458

High

883659

RIPK4
Receptor-interacting serine/threonine-protein kinase 4

1

1

High-throughput

0.445

High

283052

CIAO1
Probable cytosolic iron-sulfur protein assembly protein CIAO1

1

5

High-throughput

0.437

High

302654

FA13A
Protein FAM13A

1

1

High-throughput

0.437

High

832876

TSP3
Thrombospondin-3

1

2

High-throughput

0.437

High

856341

EFNA3
Ephrin-A3

1

2

High-throughput

0.437

High

1204608

ANKL2
Ankyrin repeat and LEM domain-containing protein 2

1

1

High-throughput

0.437

High

1237224

CCYL1
Cyclin-Y-like protein 1

1

1

High-throughput

0.437

High

1304283

GA2L1
GAS2-like protein 1

1

1

High-throughput

0.437

High

1348948

S18L2
SS18-like protein 2

1

1

High-throughput

0.437

High

1348951

TEST
Testisin

1

1

High-throughput

0.437

High

1169913

PKHG7
Pleckstrin homology domain-containing family G member 7

1

2

High-throughput

0.407

High

1348946

PP4RL
Putative serine/threonine-protein phosphatase 4 regulatory subunit 1-like

1

3

High-throughput

0.407

High

1132545

UBX11
UBX domain-containing protein 11

3

0

High-throughput

0.347

High

225066

ZNRD2
Protein ZNRD2

2

0

High-throughput

0.328

High

69257

MI4GD
MIF4G domain-containing protein

1

0

High-throughput

0.279

Low

245284

RAMP2
Receptor activity-modifying protein 2

1

0

High-throughput

0.279

Low

276282

CIB2
Calcium and integrin-binding family member 2

1

0

High-throughput

0.279

Low

277366

ST1C4
Sulfotransferase 1C4

1

0

High-throughput

0.279

Low

614233

CAH6
Carbonic anhydrase 6

1

0

High-throughput

0.279

Low

868054

VMAT1
Chromaffin granule amine transporter

1

0

High-throughput

0.279

Low

1067950

PDCD1
Programmed cell death protein 1

1

0

High-throughput

0.279

Low

1165006

SAS6
Spindle assembly abnormal protein 6 homolog

1

0

High-throughput

0.279

Low

1174566

CYS1
Cystin-1

1

0

High-throughput

0.279

Low

1203150

OSTM1
Osteopetrosis-associated transmembrane protein 1

1

0

High-throughput

0.279

Low

1232976

D2HDH
D-2-hydroxyglutarate dehydrogenase, mitochondrial

1

0

High-throughput

0.279

Low

1348059

ARL15
ADP-ribosylation factor-like protein 15

1

0

High-throughput

0.279

Low

1348947

HCST
Hematopoietic cell signal transducer

1

0

High-throughput

0.279

Low

1298212

ZDH15
Palmitoyltransferase ZDHHC15

1

0

Small-scale

0.249

Low

484537

CB27B
Putative uncharacterized protein CDRT15P3

1

0

High-throughput

0.232

Low

1012576

YL016
Putative uncharacterized protein LOC100128554

1

0

High-throughput

0.232

Low

1108491

NSN5B
Putative NOL1/NOP2/Sun domain family member 5B

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024