Protein: SEN2
tRNA-splicing endonuclease subunit Sen2 (EC 4.6.1.16) (tRNA-intron endonuclease Sen2) (HsSen2)

Gene: SEN2, TSEN2
Organism: Homo sapiens
Interactions: 47
UniProt ID: Q8NCE0

Gene Ontology (top 5):
GO:0000213 - tRNA-intron lyase activity
GO:0000214 - tRNA-intron endonuclease complex
GO:0000379 - tRNA-type intron splice site recognition and cleavage
GO:0003676 - nucleic acid binding
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1335489

SEN34
tRNA-splicing endonuclease subunit Sen34

4

1

Small-scale

0.892

High

1335480

SEN15
tRNA-splicing endonuclease subunit Sen15

4

0

Small-scale

0.846

High

1280116

SEN54
tRNA-splicing endonuclease subunit Sen54

7

0

Small-scale

0.717

High

1335481

CLP1
Polyribonucleotide 5'-hydroxyl-kinase Clp1

4

0

Small-scale

0.661

High

1335478

ZNRF1
E3 ubiquitin-protein ligase ZNRF1

2

0

High-throughput

0.585

High

1335491

TBB2B
Tubulin beta-2B chain

2

0

High-throughput

0.585

High

289361

CTAG2
Cancer/testis antigen 2

2

0

High-throughput

0.580

High

1290904

TAXB1
Tax1-binding protein 1

2

0

High-throughput

0.580

High

1335485

AP4AT
AP-4 complex accessory subunit Tepsin

2

0

High-throughput

0.580

High

1335490

THUM3
tRNA

2

0

High-throughput

0.576

High

242309

PRKN
E3 ubiquitin-protein ligase parkin

2

0

High-throughput

0.559

High

1326254

SESQ1
Sesquipedalian-1

1

1

High-throughput

0.536

High

1335482

ARL11
ADP-ribosylation factor-like protein 11

1

1

High-throughput

0.536

High

295609

CIB2
Calcium and integrin-binding family member 2

1

0

High-throughput

0.513

High

431193

LA
Lupus La protein

1

0

High-throughput

0.513

High

856811

BAG6
Large proline-rich protein BAG6

1

0

High-throughput

0.513

High

941812

ARL4C
ADP-ribosylation factor-like protein 4C

1

0

High-throughput

0.513

High

959365

RAP1B
Ras-related protein Rap-1b

1

0

High-throughput

0.513

High

1032839

XPC
DNA repair protein complementing XP-C cells

1

0

High-throughput

0.513

High

1192061

TIM50
Mitochondrial import inner membrane translocase subunit TIM50

1

0

High-throughput

0.513

High

1335486

TOX2
TOX high mobility group box family member 2

1

0

High-throughput

0.513

High

1335487

SORT
Sortilin

1

0

High-throughput

0.513

High

1335498

AKT3
RAC-gamma serine/threonine-protein kinase

1

0

High-throughput

0.513

High

1335499

NUBP2
Cytosolic Fe-S cluster assembly factor NUBP2

1

0

High-throughput

0.513

High

1335497

CAPS1
Calcium-dependent secretion activator 1

1

1

High-throughput

0.481

High

1335493

CLPB
Mitochondrial disaggregase

1

1

High-throughput

0.479

High

1335495

PKHA4
Pleckstrin homology domain-containing family A member 4

1

1

High-throughput

0.479

High

60246

A2RRN7
CADPS protein

1

1

High-throughput

0.470

High

445972

ENOA
Alpha-enolase

1

0

High-throughput

0.458

High

1144418

NONO
Non-POU domain-containing octamer-binding protein

1

0

High-throughput

0.426

High

1335484

ACD
Adrenocortical dysplasia protein homolog

1

0

High-throughput

0.426

High

1335488

RTBDN
Retbindin

3

0

High-throughput

0.347

High

1245834

TMED8
Protein TMED8

2

0

High-throughput

0.328

High

1335492

GRB1L
GREB1-like protein

2

0

High-throughput

0.328

High

1335479

GABP2
GA-binding protein subunit beta-2

2

0

High-throughput

0.316

High

64372

CDHR4
Cadherin-related family member 4

1

0

High-throughput

0.279

Low

142224

CCL22
C-C motif chemokine 22

1

0

High-throughput

0.279

Low

472192

TRFM
Melanotransferrin

1

0

High-throughput

0.279

Low

1022683

ZXDB
Zinc finger X-linked protein ZXDB

1

0

High-throughput

0.279

Low

1088272

SFSWA
Splicing factor, suppressor of white-apricot homolog

1

0

High-throughput

0.279

Low

1132164

ICAM4
Intercellular adhesion molecule 4

1

0

High-throughput

0.279

Low

1133898

NMDE3
Glutamate receptor ionotropic, NMDA 2C

1

0

High-throughput

0.279

Low

1335483

SNX21
Sorting nexin-21

1

0

High-throughput

0.279

Low

1335494

ADAM7
Disintegrin and metalloproteinase domain-containing protein 7

1

0

High-throughput

0.279

Low

1335496

VPS18
Vacuolar protein sorting-associated protein 18 homolog

1

0

High-throughput

0.279

Low

472327

CFAH
Complement factor H

1

0

Small-scale

0.249

Low

908641

PRELP
Prolargin

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025