Protein: SIL1
Nucleotide exchange factor SIL1 (BiP-associated protein) (BAP)

Gene: SIL1
Organism: Homo sapiens
Interactions: 85
UniProt ID: Q9H173

Gene Ontology (top 5):
GO:0000774 - adenyl-nucleotide exchange factor activity
GO:0005615 - extracellular space
GO:0005783 - endoplasmic reticulum
GO:0005788 - endoplasmic reticulum lumen
GO:0006457 - protein folding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

535531

BIP
Endoplasmic reticulum chaperone BiP

8

10

Small-scale

0.750

High

1334169

POC1A
POC1 centriolar protein homolog A

3

1

Small-scale

0.604

High

561387

TDGF1
Protein Cripto

2

0

High-throughput

0.602

High

1052178

COEA1
Collagen alpha-1(XIV) chain

2

0

High-throughput

0.602

High

1401693

ERGI2
Endoplasmic reticulum-Golgi intermediate compartment protein 2

2

0

High-throughput

0.602

High

880063

DNSL1
Deoxyribonuclease-1-like 1

2

0

High-throughput

0.576

High

1245920

BRID5
BRICHOS domain-containing protein 5

2

0

High-throughput

0.576

High

1185223

EDRF1
Erythroid differentiation-related factor 1

2

1

High-throughput

0.574

High

1311104

UBR1
E3 ubiquitin-protein ligase UBR1

2

1

High-throughput

0.574

High

1349432

POC1B
POC1 centriolar protein homolog B

2

1

High-throughput

0.574

High

1389500

SGTB
Small glutamine-rich tetratricopeptide repeat-containing protein beta

2

1

High-throughput

0.553

High

73852

C1T9B
Complement C1q and tumor necrosis factor-related protein 9B

2

3

High-throughput

0.549

High

976858

LCN6
Epididymal-specific lipocalin-6

2

1

High-throughput

0.549

High

1023883

2ABB
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform

2

1

High-throughput

0.549

High

1430861

UBQL1
Ubiquilin-1

1

0

High-throughput

0.549

High

1360052

LCN9
Epididymal-specific lipocalin-9

1

1

High-throughput

0.536

High

1416823

C1QT7
Complement C1q tumor necrosis factor-related protein 7

1

4

High-throughput

0.536

High

1430859

CBLN4
Cerebellin-4

1

4

High-throughput

0.536

High

1430856

Q9HCK3
KIAA1569 protein

2

1

High-throughput

0.533

High

143758

WN10B
Protein Wnt-10b

1

0

High-throughput

0.513

High

231061

VEGFD
Vascular endothelial growth factor D

1

0

High-throughput

0.513

High

273783

ATS4
A disintegrin and metalloproteinase with thrombospondin motifs 4

1

0

High-throughput

0.513

High

664084

PRTN3
Myeloblastin

1

0

High-throughput

0.513

High

908645

PRELP
Prolargin

1

0

High-throughput

0.513

High

1101417

SG2A2
Mammaglobin-A

1

0

High-throughput

0.513

High

1352982

CE192
Centrosomal protein of 192 kDa

2

1

High-throughput

0.504

High

635665

ASPG
N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase

1

0

High-throughput

0.493

High

1311170

UBR2
E3 ubiquitin-protein ligase UBR2

1

1

High-throughput

0.489

High

1326259

SESQ1
Sesquipedalian-1

1

2

High-throughput

0.489

High

1430864

ADA18
Disintegrin and metalloproteinase domain-containing protein 18

1

1

High-throughput

0.489

High

218751

TGON2
Trans-Golgi network integral membrane protein 2

1

1

High-throughput

0.479

High

566832

PDIA4
Protein disulfide-isomerase A4

1

2

High-throughput

0.479

High

1399342

SPB11
Serpin B11

1

1

High-throughput

0.479

High

951413

SC61B
Protein transport protein Sec61 subunit beta

1

0

High-throughput

0.458

High

990718

1433Z
14-3-3 protein zeta/delta

1

0

High-throughput

0.458

High

1179139

TECT1
Tectonic-1

1

0

High-throughput

0.458

High

1312596

FA20C
Extracellular serine/threonine protein kinase FAM20C

1

0

High-throughput

0.458

High

1383061

LRC59
Leucine-rich repeat-containing protein 59

1

0

High-throughput

0.458

High

1396539

CALR3
Calreticulin-3

1

0

High-throughput

0.458

High

1412978

CNPY3
Protein canopy homolog 3

1

0

Small-scale

0.458

High

1430854

SIL1
Nucleotide exchange factor SIL1

1

0

Small-scale

0.458

High

104035

F5GYW9
Serpin family B member 11

1

1

High-throughput

0.445

High

388801

C1QC
Complement C1q subcomponent subunit C

1

5

High-throughput

0.445

High

714736

KAIN
Kallistatin

1

2

High-throughput

0.445

High

801519

HSPA9
Stress-70 protein, mitochondrial

1

12

Small-scale

0.445

High

1430860

DJB11
DnaJ homolog subfamily B member 11

1

1

Small-scale

0.445

High

937905

FOXA1
Hepatocyte nuclear factor 3-alpha

1

2

High-throughput

0.437

High

1255484

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.437

High

1228185

OLM2B
Olfactomedin-like protein 2B

1

0

High-throughput

0.426

High

1332764

PMGT2
Protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2

1

0

High-throughput

0.426

High

1430863

KLK5
Kallikrein-5

1

0

High-throughput

0.426

High

388665

C1QA
Complement C1q subcomponent subunit A

1

3

High-throughput

0.407

High

1430862

PRG3
Proteoglycan 3

1

1

High-throughput

0.407

High

1143788

PON2
Serum paraoxonase/arylesterase 2

3

0

High-throughput

0.347

High

1335601

GLBL3
Beta-galactosidase-1-like protein 3

3

0

High-throughput

0.347

High

1006222

CNTP1
Contactin-associated protein 1

2

0

High-throughput

0.328

High

1388584

OMA1
Metalloendopeptidase OMA1, mitochondrial

2

0

High-throughput

0.328

High

1395445

FEM1C
Protein fem-1 homolog C

2

0

Small-scale

0.317

High

1295034

TMM25
Transmembrane protein 25

2

0

High-throughput

0.313

High

1359238

CA054
Uncharacterized protein C1orf54

2

0

High-throughput

0.313

High

1163809

PTPRO
Receptor-type tyrosine-protein phosphatase O

2

0

High-throughput

0.305

High

154882

ISLR
Immunoglobulin superfamily containing leucine-rich repeat protein

1

0

High-throughput

0.279

Low

191465

SIA8E
Alpha-2,8-sialyltransferase 8E

1

0

High-throughput

0.279

Low

268937

FCG3B
Low affinity immunoglobulin gamma Fc region receptor III-B

1

0

High-throughput

0.279

Low

355376

B3GT4
Beta-1,3-galactosyltransferase 4

1

0

High-throughput

0.279

Low

647405

IDS
Iduronate 2-sulfatase

1

0

High-throughput

0.279

Low

1034817

NAAA
N-acylethanolamine-hydrolyzing acid amidase

1

0

High-throughput

0.279

Low

1116299

PTC1
Protein patched homolog 1

1

0

High-throughput

0.279

Low

1144253

PGFRL
Platelet-derived growth factor receptor-like protein

1

0

High-throughput

0.279

Low

1260718

KNDC1
Kinase non-catalytic C-lobe domain-containing protein 1

1

0

High-throughput

0.279

Low

1395165

HIPL1
HHIP-like protein 1

1

0

High-throughput

0.279

Low

1430735

SIRPD
Signal-regulatory protein delta

1

0

High-throughput

0.279

Low

1430855

DPEP2
Dipeptidase 2

1

0

High-throughput

0.279

Low

181939

SMAD9
Mothers against decapentaplegic homolog 9

1

0

High-throughput

0.265

Low

718909

CCND3
G1/S-specific cyclin-D3

1

0

High-throughput

0.251

Low

1252223

SYNE3
Nesprin-3

1

0

High-throughput

0.249

Low

1430858

FBX6
F-box only protein 6

1

0

High-throughput

0.249

Low

248241

NDK8
Putative nucleoside diphosphate kinase

1

0

High-throughput

0.232

Low

327084

NXPH3
Neurexophilin-3

1

0

High-throughput

0.232

Low

332242

UCP5
Brain mitochondrial carrier protein 1

1

0

High-throughput

0.232

Low

412980

CPNS1
Calpain small subunit 1

1

0

Small-scale

0.232

Low

456012

ASGR2
Asialoglycoprotein receptor 2

1

0

High-throughput

0.232

Low

1382057

T106A
Transmembrane protein 106A

1

0

High-throughput

0.232

Low

1430857

PLXA4
Plexin-A4

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025