Protein: SPS1
Selenide, water dikinase 1 (EC 2.7.9.3) (Selenium donor protein 1) (Selenophosphate synthase 1)

Gene: SPS1, SEPHS1
Organism: Homo sapiens
Interactions: 49
UniProt ID: P49903

Gene Ontology (top 5):
GO:0004756 - selenide, water dikinase activity
GO:0005524 - ATP binding
GO:0005525 - GTP binding
GO:0005737 - cytoplasm
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

892285

SPS1
Selenide, water dikinase 1

6

1

High-throughput

0.949

High

892308

SPS2
Selenide, water dikinase 2

5

1

High-throughput

0.915

High

892294

QRIC1
Transcriptional regulator QRICH1

4

0

High-throughput

0.674

High

892295

XAF1
XIAP-associated factor 1

2

0

High-throughput

0.580

High

892318

ZRAN1
Ubiquitin thioesterase ZRANB1

2

0

High-throughput

0.559

High

736907

GBP2
Guanylate-binding protein 2

1

0

High-throughput

0.518

High

529352

TAU
Microtubule-associated protein tau

1

0

High-throughput

0.513

High

892290

CUL3
Cullin-3

1

0

High-throughput

0.513

High

892311

ASPC1
Tether containing UBX domain for GLUT4

1

0

High-throughput

0.513

High

892310

CDCA4
Cell division cycle-associated protein 4

1

0

High-throughput

0.486

High

892297

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.479

High

536759

HSP7C
Heat shock cognate 71 kDa protein

1

0

High-throughput

0.458

High

720870

KPYR
Pyruvate kinase PKLR

1

0

High-throughput

0.458

High

872077

SOX2
Transcription factor SOX-2

1

0

High-throughput

0.458

High

892286

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

0

High-throughput

0.458

High

892287

T2R41
Taste receptor type 2 member 41

1

0

High-throughput

0.458

High

892303

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

0

High-throughput

0.458

High

892317

TR10D
Tumor necrosis factor receptor superfamily member 10D

1

0

High-throughput

0.458

High

142306

PEX7
Peroxisomal targeting signal 2 receptor

1

0

High-throughput

0.426

High

892298

DND1
Dead end protein homolog 1

1

0

High-throughput

0.426

High

892304

P33MX
Putative monooxygenase p33MONOX

1

0

High-throughput

0.426

High

892313

LN28A
Protein lin-28 homolog A

1

0

High-throughput

0.426

High

892314

ITM2C
Integral membrane protein 2C

1

0

High-throughput

0.426

High

892316

DDX28
Probable ATP-dependent RNA helicase DDX28

1

0

High-throughput

0.426

High

664370

ZBT25
Zinc finger and BTB domain-containing protein 25

4

0

High-throughput

0.367

High

892292

HLX
H2.0-like homeobox protein

2

0

High-throughput

0.328

High

326403

ZN202
Zinc finger protein 202

2

0

High-throughput

0.316

High

892296

ZN474
Zinc finger protein 474

2

0

High-throughput

0.316

High

892300

ZN276
Zinc finger protein 276

2

0

High-throughput

0.316

High

892302

ZN526
Zinc finger protein 526

2

0

High-throughput

0.316

High

892320

PLAL2
Zinc finger protein PLAGL2

2

0

High-throughput

0.316

High

639587

SAT1
Diamine acetyltransferase 1

1

0

High-throughput

0.282

High

892289

U119A
Protein unc-119 homolog A

1

0

High-throughput

0.282

High

892291

DPYL1
Dihydropyrimidinase-related protein 1

1

0

High-throughput

0.282

High

892299

S35F6
Solute carrier family 35 member F6

1

0

High-throughput

0.282

High

892305

SACA9
Sperm acrosome-associated protein 9

1

0

High-throughput

0.282

High

892306

IGS21
Immunoglobulin superfamily member 21

1

0

High-throughput

0.282

High

892319

ERG28
Ergosterol biosynthetic protein 28 homolog

1

0

High-throughput

0.282

High

892307

DEPD7
DEP domain-containing protein 7

1

0

High-throughput

0.251

Low

254559

EIF1B
Eukaryotic translation initiation factor 1b

1

0

High-throughput

0.249

Low

569240

YJU2B
Probable splicing factor YJU2B

1

0

High-throughput

0.249

Low

892315

DISC1
Disrupted in schizophrenia 1 protein

1

0

High-throughput

0.238

Low

183612

RT12
Small ribosomal subunit protein uS12m

1

0

High-throughput

0.232

Low

892288

RM49
Large ribosomal subunit protein mL49

1

0

High-throughput

0.232

Low

892293

ISX
Intestine-specific homeobox

1

0

High-throughput

0.232

Low

892301

TTC9C
Tetratricopeptide repeat protein 9C

1

0

High-throughput

0.232

Low

892309

OSB11
Oxysterol-binding protein-related protein 11

1

0

High-throughput

0.232

Low

892312

CAD23
Cadherin-23

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025