Protein: SHSA6
Protein shisa-6

Gene: SHSA6, SHISA6
Organism: Homo sapiens
Interactions: 43
UniProt ID: Q6ZSJ9

Gene Ontology (top 5):
GO:0007283 - spermatogenesis
GO:0014069 - postsynaptic density
GO:0016055 - Wnt signaling pathway
GO:0030165 - PDZ domain binding
GO:0032281 - AMPA glutamate receptor complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

269251

HSF2B
Heat shock factor 2-binding protein

2

0

High-throughput

0.580

High

861660

NEDD4
E3 ubiquitin-protein ligase NEDD4

2

0

High-throughput

0.580

High

1061747

TLE5
TLE family member 5

2

0

High-throughput

0.580

High

1254158

TSSK3
Testis-specific serine/threonine-protein kinase 3

2

0

High-throughput

0.580

High

1254159

PFD5
Prefoldin subunit 5

2

0

High-throughput

0.580

High

1151559

TRIP6
Thyroid receptor-interacting protein 6

2

2

High-throughput

0.553

High

1201839

PKHG4
Puratrophin-1

2

2

High-throughput

0.553

High

1254153

FBLI1
Filamin-binding LIM protein 1

2

2

High-throughput

0.553

High

1110265

KCC2B
Calcium/calmodulin-dependent protein kinase type II subunit beta

1

2

High-throughput

0.536

High

1110363

KCC2G
Calcium/calmodulin-dependent protein kinase type II subunit gamma

1

2

High-throughput

0.536

High

1110479

KCC2D
Calcium/calmodulin-dependent protein kinase type II subunit delta

1

2

High-throughput

0.536

High

1254166

KLH42
Kelch-like protein 42

1

1

High-throughput

0.489

High

1193608

Q49AR9
ANKS1A protein

1

1

High-throughput

0.470

High

1254150

SHSA6
Protein shisa-6

1

0

High-throughput

0.460

High

872456

SOX2
Transcription factor SOX-2

1

0

High-throughput

0.458

High

1254154

ANS1A
Ankyrin repeat and SAM domain-containing protein 1A

1

1

High-throughput

0.439

High

255085

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

0

High-throughput

0.426

High

70301

CRTP1
Cysteine-rich tail protein 1

2

0

High-throughput

0.316

High

217126

MS18B
Protein Mis18-beta

2

0

High-throughput

0.316

High

302865

CIAO1
Probable cytosolic iron-sulfur protein assembly protein CIAO1

2

0

High-throughput

0.316

High

347772

BAG3
BAG family molecular chaperone regulator 3

2

0

High-throughput

0.316

High

808100

CDN1A
Cyclin-dependent kinase inhibitor 1

2

0

High-throughput

0.316

High

941475

CTBP2
C-terminal-binding protein 2

2

0

High-throughput

0.316

High

943782

UBS3A
Ubiquitin-associated and SH3 domain-containing protein A

2

0

High-throughput

0.316

High

1063365

GOGA2
Golgin subfamily A member 2

2

0

High-throughput

0.316

High

1145998

K1H1
Keratin, type I cuticular Ha1

2

0

High-throughput

0.316

High

1179965

CCD57
Coiled-coil domain-containing protein 57

2

0

High-throughput

0.316

High

1231751

TTC19
Tetratricopeptide repeat protein 19, mitochondrial

2

0

High-throughput

0.316

High

1254152

LMO3
LIM domain only protein 3

2

0

High-throughput

0.316

High

1254155

KAT5
Histone acetyltransferase KAT5

2

0

High-throughput

0.316

High

1254157

SMRD1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1

2

0

High-throughput

0.316

High

1254160

KIFC3
Kinesin-like protein KIFC3

2

0

High-throughput

0.316

High

1254161

KRA33
Keratin-associated protein 3-3

2

0

High-throughput

0.316

High

1254162

CARD9
Caspase recruitment domain-containing protein 9

2

0

High-throughput

0.316

High

1254163

ARMC7
Armadillo repeat-containing protein 7

2

0

High-throughput

0.316

High

1254164

KIF9
Kinesin-like protein KIF9

2

0

High-throughput

0.316

High

1254165

EXOS5
Exosome complex component RRP46

2

0

High-throughput

0.316

High

320827

KLH18
Kelch-like protein 18

1

0

High-throughput

0.279

Low

1254151

SELH
Selenoprotein H

1

0

High-throughput

0.279

Low

1254156

PTER
N-acetyltaurine hydrolase

1

0

High-throughput

0.279

Low

1254167

NAGK
N-acetyl-D-glucosamine kinase

1

0

High-throughput

0.279

Low

1254168

TRPV2
Transient receptor potential cation channel subfamily V member 2

1

0

Small-scale

0.238

Low


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Last updated: 11Aug2025