Protein: CATC
Dipeptidyl peptidase 1 (EC 3.4.14.1) (Cathepsin C) (Cathepsin J) (Dipeptidyl peptidase I) (DPP-I) (DPPI) (Dipeptidyl transferase) [Cleaved into: Dipeptidyl peptidase 1 exclusion domain chain (Dipeptidyl peptidase I exclusion domain chain); Dipeptidyl peptidase 1 heavy chain (Dipeptidyl peptidase I heavy chain); Dipeptidyl peptidase 1 light chain (Dipeptidyl peptidase I light chain)]

Gene: CATC, CTSC
Organism: Homo sapiens
Interactions: 39
UniProt ID: P53634

Gene Ontology (top 5):
GO:0001913 - T cell mediated cytotoxicity
GO:0004197 - cysteine-type endopeptidase activity
GO:0004252 - serine-type endopeptidase activity
GO:0005576 - extracellular region
GO:0005615 - extracellular space

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

922219

CYTM
Cystatin-M

2

17

High-throughput

0.776

High

370035

CYTC
Cystatin-C

1

17

High-throughput

0.691

High

370282

CYTA
Cystatin-A

1

9

High-throughput

0.691

High

303705

CYTF
Cystatin-F

1

17

Small-scale

0.618

High

922215

CATC
Dipeptidyl peptidase 1

1

11

High-throughput

0.618

High

922226

WFDC9
Protein WFDC9

2

0

High-throughput

0.602

High

922225

NHLC2
NHL repeat-containing protein 2

2

1

High-throughput

0.584

High

922230

FBX6
F-box only protein 6

2

6

High-throughput

0.584

High

72927

ESPN
Espin

1

0

High-throughput

0.578

High

922218

G3BP1
Ras GTPase-activating protein-binding protein 1

2

1

High-throughput

0.574

High

548449

MPRI
Cation-independent mannose-6-phosphate receptor

1

8

High-throughput

0.536

High

733315

CCR1
C-C chemokine receptor type 1

1

2

High-throughput

0.536

High

853634

MK08
Mitogen-activated protein kinase 8

1

2

High-throughput

0.536

High

922232

SAE1
SUMO-activating enzyme subunit 1

1

2

High-throughput

0.536

High

922235

RBM8A
RNA-binding protein 8A

1

1

High-throughput

0.536

High

400529

RAF1
RAF proto-oncogene serine/threonine-protein kinase

2

6

High-throughput

0.533

High

922222

SPRE1
Sprouty-related, EVH1 domain-containing protein 1

1

1

High-throughput

0.515

High

341918

CEP43
Centrosomal protein 43

1

0

High-throughput

0.513

High

922220

SGO1
Shugoshin 1

1

0

High-throughput

0.513

High

922227

TBC16
TBC1 domain family member 16

1

4

High-throughput

0.489

High

457066

CAN1
Calpain-1 catalytic subunit

1

1

Small-scale

0.481

High

922228

XRN2
5'-3' exoribonuclease 2

1

2

High-throughput

0.481

High

217997

TGON2
Trans-Golgi network integral membrane protein 2

1

3

High-throughput

0.479

High

377471

INS
Insulin [Cleaved into: Insulin B chain; Insulin A chain]

1

1

High-throughput

0.479

High

590843

TIMP2
Metalloproteinase inhibitor 2

1

1

High-throughput

0.479

High

861942

YAP1
Transcriptional coactivator YAP1

1

3

Small-scale

0.479

High

922223

TM192
Transmembrane protein 192

1

1

High-throughput

0.479

High

922231

T106B
Transmembrane protein 106B

1

2

High-throughput

0.479

High

922233

ZRAN1
Ubiquitin thioesterase ZRANB1

1

2

High-throughput

0.479

High

109386

G5E9A7
DM1 locus, WD repeat containing

1

3

High-throughput

0.470

High

402347

GBA1
Lysosomal acid glucosylceramidase

1

0

Small-scale

0.458

High

922216

TERA
Transitional endoplasmic reticulum ATPase

1

0

High-throughput

0.458

High

922217

RNF4
E3 ubiquitin-protein ligase RNF4

1

0

High-throughput

0.458

High

922224

POC5
Centrosomal protein POC5

1

1

High-throughput

0.445

High

922221

TRI67
Tripartite motif-containing protein 67

1

4

High-throughput

0.437

High

213095

CP110
Centriolar coiled-coil protein of 110 kDa

1

0

High-throughput

0.426

High

922229

PPDPF
Pancreatic progenitor cell differentiation and proliferation factor

1

0

Small-scale

0.251

Low

922234

SRP68
Signal recognition particle subunit SRP68

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025