Protein: SAP30
Histone deacetylase complex subunit SAP30 (30 kDa Sin3-associated polypeptide) (Sin3 corepressor complex subunit SAP30) (Sin3-associated polypeptide p30)

Gene: SAP30
Organism: Homo sapiens
Interactions: 136
UniProt ID: O75446

Gene Ontology (top 5):
GO:0000118 - histone deacetylase complex
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0003677 - DNA binding
GO:0003712 - transcription coregulator activity
GO:0003714 - transcription corepressor activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

265246

SIN3A
Paired amphipathic helix protein Sin3a

16

4

Small-scale

0.986

High

257729

SIN3B
Paired amphipathic helix protein Sin3b

4

4

Small-scale

0.892

High

265201

HDAC1
Histone deacetylase 1

18

7

Small-scale

0.765

High

265235

HDAC2
Histone deacetylase 2

13

7

Small-scale

0.759

High

265211

RBBP7
Histone-binding protein RBBP7

10

4

Small-scale

0.756

High

265193

RBBP4
Histone-binding protein RBBP4

9

4

Small-scale

0.755

High

265277

ING1
Inhibitor of growth protein 1

5

7

Small-scale

0.721

High

265188

FOXK2
Forkhead box protein K2

4

2

Small-scale

0.704

High

265174

ARI4A
AT-rich interactive domain-containing protein 4A

4

1

Small-scale

0.703

High

265257

ING2
Inhibitor of growth protein 2

4

6

Small-scale

0.699

High

265266

SHCAF
SIN3-HDAC complex-associated factor

4

1

Small-scale

0.699

High

265217

BRM1L
Breast cancer metastasis-suppressor 1-like protein

4

3

Small-scale

0.694

High

265185

FOXK1
Forkhead box protein K1

3

2

High-throughput

0.675

High

265214

ARI4B
AT-rich interactive domain-containing protein 4B

3

1

High-throughput

0.667

High

265261

SDS3
Sin3 histone deacetylase corepressor complex component SDS3

3

3

High-throughput

0.667

High

265256

SP130
Histone deacetylase complex subunit SAP130

3

3

High-throughput

0.656

High

265264

BRMS1
Breast cancer metastasis-suppressor 1

3

3

Small-scale

0.656

High

179004

TNC18
Trinucleotide repeat-containing gene 18 protein

2

1

High-throughput

0.628

High

265219

ZN704
Zinc finger protein 704

2

2

High-throughput

0.628

High

265251

PHF23
PHD finger protein 23

2

0

High-throughput

0.602

High

261354

NCOR1
Nuclear receptor corepressor 1

2

4

Small-scale

0.585

High

197933

PHF1
PHD finger protein 1

2

1

Small-scale

0.584

High

265205

CHD4
Chromodomain-helicase-DNA-binding protein 4

2

4

Small-scale

0.584

High

265209

EZH2
Histone-lysine N-methyltransferase EZH2

2

2

High-throughput

0.584

High

265232

GATD1
GATA zinc finger domain-containing protein 1

2

1

High-throughput

0.584

High

265244

PHF12
PHD finger protein 12

2

5

Small-scale

0.584

High

265252

MAD3
Max dimerization protein 3

2

5

High-throughput

0.574

High

265272

BAHC1
BAH and coiled-coil domain-containing protein 1

2

1

High-throughput

0.574

High

265162

MTA2
Metastasis-associated protein MTA2

2

2

Small-scale

0.571

High

265247

UHRF1
E3 ubiquitin-protein ligase UHRF1

1

3

Small-scale

0.561

High

265262

ZN395
Zinc finger protein 395

1

2

Small-scale

0.561

High

265202

CUL4B
Cullin-4B

2

0

Small-scale

0.559

High

265171

TYY1
Transcriptional repressor protein YY1

1

0

Small-scale

0.549

High

265269

SAMN1
SAM domain-containing protein SAMSN-1

1

0

Small-scale

0.537

High

265170

CSK22
Casein kinase II subunit alpha'

1

1

High-throughput

0.536

High

265180

MAX
Protein max

1

3

High-throughput

0.536

High

265184

CSK21
Casein kinase II subunit alpha

1

1

High-throughput

0.536

High

265203

FHL2
Four and a half LIM domains protein 2

1

1

High-throughput

0.536

High

265222

TF2LX
Homeobox protein TGIF2LX

1

3

High-throughput

0.536

High

265255

TGIF2
Homeobox protein TGIF2

1

3

High-throughput

0.536

High

265263

SP30L
Histone deacetylase complex subunit SAP30L

1

1

High-throughput

0.536

High

265283

NCOR2
Nuclear receptor corepressor 2

1

4

Small-scale

0.536

High

265182

PHS
Pterin-4-alpha-carbinolamine dehydratase

1

0

High-throughput

0.518

High

265190

ID3
DNA-binding protein inhibitor ID-3

1

0

High-throughput

0.518

High

173356

CLIC2
Chloride intracellular channel protein 2

1

0

High-throughput

0.513

High

265167

PARP1
Poly [ADP-ribose] polymerase 1

1

0

High-throughput

0.513

High

265168

H2AZ
Histone H2A.Z

1

0

High-throughput

0.513

High

265181

RL15
Large ribosomal subunit protein eL15

1

0

High-throughput

0.513

High

265187

MDM2
E3 ubiquitin-protein ligase Mdm2

1

0

High-throughput

0.513

High

265204

SMC1A
Structural maintenance of chromosomes protein 1A

1

0

High-throughput

0.513

High

265212

DECR
2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing], mitochondrial

1

0

High-throughput

0.513

High

265240

ADAT3
Probable inactive tRNA-specific adenosine deaminase-like protein 3

1

0

High-throughput

0.513

High

265249

BCL7B
B-cell CLL/lymphoma 7 protein family member B

1

0

High-throughput

0.513

High

265265

SRA1
Steroid receptor RNA activator 1

1

0

High-throughput

0.513

High

265268

MBNL1
Muscleblind-like protein 1

1

0

High-throughput

0.513

High

265271

GAR1
H/ACA ribonucleoprotein complex subunit 1

1

0

High-throughput

0.513

High

265279

ABT1
Activator of basal transcription 1

1

0

High-throughput

0.513

High

265192

MAD1
Max dimerization protein 1

1

5

Small-scale

0.501

High

265260

RPF2
Ribosome production factor 2 homolog

1

0

High-throughput

0.493

High

265163

BAG3
BAG family molecular chaperone regulator 3

1

0

High-throughput

0.493

High

265175

SYUA
Alpha-synuclein

1

0

High-throughput

0.493

High

265177

HD
Huntingtin

1

0

High-throughput

0.493

High

265186

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.493

High

265189

NC2B
Protein Dr1

1

0

High-throughput

0.493

High

265225

PIAS4
E3 SUMO-protein ligase PIAS4

1

0

High-throughput

0.493

High

265234

NDRG1
Protein NDRG1

1

0

High-throughput

0.493

High

265237

APBB2
Amyloid beta precursor protein binding family B member 2

1

0

High-throughput

0.493

High

265282

TF3C3
General transcription factor 3C polypeptide 3

1

0

High-throughput

0.493

High

265220

CIR1
Corepressor interacting with RBPJ 1

1

0

Small-scale

0.486

High

265213

H2B2E
Histone H2B type 2-E

1

0

Small-scale

0.480

High

177154

HDAC3
Histone deacetylase 3

1

7

Small-scale

0.479

High

229256

SMCA5
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5

1

5

High-throughput

0.479

High

233803

HBP1
HMG box-containing protein 1

1

3

High-throughput

0.479

High

243702

BRD4
Bromodomain-containing protein 4

1

1

High-throughput

0.479

High

265164

MBD3
Methyl-CpG-binding domain protein 3

1

2

High-throughput

0.479

High

265165

MYCN
N-myc proto-oncogene protein

1

5

High-throughput

0.479

High

265173

SMCA1
Probable global transcription activator SNF2L1

1

5

High-throughput

0.479

High

265179

SMCA2
Probable global transcription activator SNF2L2

1

5

Small-scale

0.479

High

265183

H4
Histone H4

1

1

High-throughput

0.479

High

265191

KMT2A
Histone-lysine N-methyltransferase 2A

1

2

Small-scale

0.479

High

265194

BPTF
Nucleosome-remodeling factor subunit BPTF

1

5

High-throughput

0.479

High

265195

CHD3
Chromodomain-helicase-DNA-binding protein 3

1

5

High-throughput

0.479

High

265198

TIF1B
Transcription intermediary factor 1-beta

1

1

High-throughput

0.479

High

265199

MTA1
Metastasis-associated protein MTA1

1

2

High-throughput

0.479

High

265206

SHPRH
E3 ubiquitin-protein ligase SHPRH

1

6

High-throughput

0.479

High

265221

P66A
Transcriptional repressor p66-alpha

1

1

High-throughput

0.479

High

265227

CHD5
Chromodomain-helicase-DNA-binding protein 5

1

4

High-throughput

0.479

High

265231

ZN296
Zinc finger protein 296

1

2

High-throughput

0.479

High

265233

P66B
Transcriptional repressor p66-beta

1

1

High-throughput

0.479

High

265236

EZH1
Histone-lysine N-methyltransferase EZH1

1

2

High-throughput

0.479

High

265245

CIC
Protein capicua homolog

1

2

High-throughput

0.479

High

265250

MTA3
Metastasis-associated protein MTA3

1

5

High-throughput

0.479

High

265254

BC11B
B-cell lymphoma/leukemia 11B

1

2

High-throughput

0.479

High

265258

BC11A
B-cell lymphoma/leukemia 11A

1

2

High-throughput

0.479

High

265274

MBD2
Methyl-CpG-binding domain protein 2

1

2

High-throughput

0.479

High

265276

HMGX4
HMG domain-containing protein 4

1

2

High-throughput

0.479

High

265278

BRPF3
Bromodomain and PHD finger-containing protein 3

1

1

High-throughput

0.479

High

265281

MTF2
Metal-response element-binding transcription factor 2

1

1

High-throughput

0.479

High

265172

ELAV4
ELAV-like protein 4

1

1

High-throughput

0.470

High

265176

VHL
von Hippel-Lindau disease tumor suppressor

1

0

Small-scale

0.460

High

146780

CDKA1
Cyclin-dependent kinase 2-associated protein 1

1

0

High-throughput

0.458

High

158712

HAT1
Histone acetyltransferase type B catalytic subunit

1

0

High-throughput

0.458

High

265161

EED
Polycomb protein EED

1

0

High-throughput

0.458

High

265166

RET1
Retinol-binding protein 1

1

0

Small-scale

0.458

High

265169

MYBB
Myb-related protein B

1

0

High-throughput

0.458

High

265178

TAF6
Transcription initiation factor TFIID subunit 6

1

0

Small-scale

0.458

High

265196

CAF1A
Chromatin assembly factor 1 subunit A

1

0

High-throughput

0.458

High

265197

CAF1B
Chromatin assembly factor 1 subunit B

1

0

High-throughput

0.458

High

265200

CTBP1
C-terminal-binding protein 1

1

0

High-throughput

0.458

High

265207

SUZ12
Polycomb protein SUZ12

1

0

High-throughput

0.458

High

265210

DDB1
DNA damage-binding protein 1

1

0

Small-scale

0.458

High

265215

LIN52
Protein lin-52 homolog

1

0

High-throughput

0.458

High

265218

LIN9
Protein lin-9 homolog

1

0

High-throughput

0.458

High

265224

BAP18
Chromatin complexes subunit BAP18

1

0

High-throughput

0.458

High

265226

HJURP
Holliday junction recognition protein

1

0

High-throughput

0.458

High

265228

SAP25
Histone deacetylase complex subunit SAP25

1

0

Small-scale

0.458

High

265229

UBS3B
Ubiquitin-associated and SH3 domain-containing protein B

1

0

Small-scale

0.458

High

265239

SIR1
NAD-dependent protein deacetylase sirtuin-1

1

0

Small-scale

0.458

High

265241

LIN37
Protein lin-37 homolog

1

0

High-throughput

0.458

High

265242

Z512B
Zinc finger protein 512B

1

0

High-throughput

0.458

High

265243

PWP2A
PWWP domain-containing protein 2A

1

0

High-throughput

0.458

High

265253

DPY30
Protein dpy-30 homolog

1

0

High-throughput

0.458

High

265273

ZN219
Zinc finger protein 219

1

0

High-throughput

0.458

High

92527

E9PJF5
BRMS1 transcriptional repressor and anoikis regulator

1

3

High-throughput

0.445

High

110766

H7BXF5
Sin3A associated protein 130

1

3

High-throughput

0.445

High

265280

TRI33
E3 ubiquitin-protein ligase TRIM33

1

1

Small-scale

0.445

High

265223

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

Small-scale

0.438

High

265208

EBP
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase

1

0

High-throughput

0.279

Low

265216

ACTBL
Beta-actin-like protein 2

1

0

High-throughput

0.279

Low

265230

CO040
UPF0235 protein C15orf40

1

0

High-throughput

0.279

Low

265238

CMBL
Carboxymethylenebutenolidase homolog

1

0

High-throughput

0.279

Low

265248

LYST
Lysosomal-trafficking regulator

1

0

High-throughput

0.279

Low

265267

ZCC17
Zinc finger CCHC domain-containing protein 17

1

0

High-throughput

0.279

Low

265275

DKK2
Dickkopf-related protein 2

1

0

High-throughput

0.279

Low

265259

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.249

Low

265270

RM22
Large ribosomal subunit protein uL22m

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024