Protein: GPA1
Guanine nucleotide-binding protein alpha-1 subunit (GP1-alpha)

Gene: GPA1
Organism: Saccharomyces cerevisiae S288C
Interactions: 41
UniProt ID: P08539

Gene Ontology (top 5):
GO:0000742 - karyogamy involved in conjugation with cellular fusion
GO:0000743 - nuclear migration involved in conjugation with cellular fusion
GO:0000750 - pheromone-dependent signal transduction involved in conjugation with cellular fusion
GO:0001664 - G protein-coupled receptor binding
GO:0003924 - GTPase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

470733

GBB
Guanine nucleotide-binding protein subunit beta

20

20

Small-scale

0.989

High

470730

SST2
Protein SST2

5

0

Small-scale

0.878

High

94526

STE2
Pheromone alpha factor receptor

4

0

Small-scale

0.840

High

470729

GPA2
Guanine nucleotide-binding protein alpha-2 subunit

2

13

Small-scale

0.799

High

470731

FUS3
Mitogen-activated protein kinase FUS3

3

3

Small-scale

0.670

High

470734

GBG
Guanine nucleotide-binding protein subunit gamma

4

0

Small-scale

0.651

High

470735

VPS15
Serine/threonine-protein kinase VPS15

2

5

Small-scale

0.634

High

470750

MET30
F-box protein MET30

1

3

Small-scale

0.621

High

470728

GPA1
Guanine nucleotide-binding protein alpha-1 subunit

1

14

High-throughput

0.618

High

470763

RGS2
Regulator of G-protein signaling 2

1

1

Small-scale

0.618

High

470762

GET3
ATPase GET3

2

0

Small-scale

0.605

High

460699

CDC4
Cell division control protein 4

1

3

Small-scale

0.579

High

470737

VPS34
Phosphatidylinositol 3-kinase VPS34

1

4

Small-scale

0.578

High

438565

SC160
Protein SCP160

2

2

Small-scale

0.576

High

470742

ELM1
Serine/threonine-protein kinase ELM1

1

1

Small-scale

0.561

High

470755

REG1
Resistance to glucose repression protein 1

2

0

Small-scale

0.559

High

470759

NAA40
N-alpha-acetyltransferase 40

2

0

Small-scale

0.551

High

470749

SAK1
SNF1-activating kinase 1

1

0

Small-scale

0.537

High

454679

KAPR
cAMP-dependent protein kinase regulatory subunit

1

11

Small-scale

0.481

High

470732

KAR3
Kinesin-like protein KAR3

1

8

Small-scale

0.479

High

470741

SP110
Spindle pole body component 110

1

6

Small-scale

0.479

High

470752

UBP12
Ubiquitin carboxyl-terminal hydrolase 12

1

5

Small-scale

0.479

High

470756

MDM1
Structural protein MDM1

1

5

Small-scale

0.479

High

470761

YP191
Ubiquitin carboxyl-terminal hydrolase MIY1

1

1

Small-scale

0.479

High

470751

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.458

High

470754

CTU2
Cytoplasmic tRNA 2-thiolation protein 2

1

0

Small-scale

0.458

High

470758

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.458

High

470760

RAX1
Bud site selection protein RAX1

1

0

Small-scale

0.458

High

470738

MAS5
Mitochondrial protein import protein MAS5

1

0

High-throughput

0.426

High

470740

HS104
Heat shock protein 104

1

0

High-throughput

0.426

High

470736

RPC2
DNA-directed RNA polymerase III subunit RPC2

1

0

High-throughput

0.249

Low

470743

SC61A
Protein transport protein SEC61

1

0

High-throughput

0.249

Low

470744

NU170
Nucleoporin NUP170

1

0

High-throughput

0.249

Low

470748

MDM31
Mitochondrial distribution and morphology protein 31

1

0

Small-scale

0.249

Low

470753

DSN1
Kinetochore-associated protein DSN1

1

0

High-throughput

0.249

Low

470739

GAC1
Serine/threonine-protein phosphatase 1 regulatory subunit GAC1

1

0

High-throughput

0.238

Low

470745

YBW6
Putative uncharacterized protein YBR116C

1

0

High-throughput

0.238

Low

470746

ATG14
Autophagy-related protein 14

1

0

High-throughput

0.238

Low

470747

YHC6
Uncharacterized protein YHL026C

1

0

High-throughput

0.238

Low

470757

CSN9
COP9 signalosome complex subunit 9

1

0

High-throughput

0.238

Low


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Last updated: 11Aug2025