Protein: ERG9
Squalene synthase ERG9 (SQS) (SS) (EC 2.5.1.21) (Ergosterol biosynthetic protein 9) (FPP:FPP farnesyltransferase ERG9) (Farnesyl-diphosphate farnesyltransferase ERG9)

Gene: ERG9
Organism: Saccharomyces cerevisiae S288C
Interactions: 42
UniProt ID: P29704

Gene Ontology (top 5):
GO:0005739 - mitochondrion
GO:0005741 - mitochondrial outer membrane
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0006696 - ergosterol biosynthetic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

715043

ERG26
Sterol-4-alpha-carboxylate 3-dehydrogenase ERG26, decarboxylating

2

2

Small-scale

0.614

High

578991

HSC82
ATP-dependent molecular chaperone HSC82

2

1

High-throughput

0.584

High

715039

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

2

0

High-throughput

0.559

High

715026

ERG3
Delta(7)-sterol 5(6)-desaturase ERG3

1

1

Small-scale

0.541

High

715042

ERG25
C-4 methylsterol oxidase ERG25

1

1

Small-scale

0.541

High

715053

ERG27
3-keto-steroid reductase ERG27

1

1

Small-scale

0.541

High

528559

CP51
Lanosterol 14-alpha demethylase CYP51

1

0

Small-scale

0.518

High

668884

ERG6
Sterol 24-C-methyltransferase ERG6

1

0

Small-scale

0.518

High

715034

ERG28
Ergosterol biosynthetic protein 28

1

0

Small-scale

0.518

High

715038

UFE1
Syntaxin UFE1

1

0

High-throughput

0.518

High

715037

ELO3
Fatty acid elongase 3

1

1

High-throughput

0.479

High

715046

APJ1
J domain-containing protein APJ1

1

1

High-throughput

0.479

High

94600

CMC1
Truncated non-functional calcium-binding mitochondrial carrier SAL1-1

1

0

High-throughput

0.460

High

506388

YK104
Putative uncharacterized protein YKR104W

1

0

High-throughput

0.460

High

715029

PET10
Protein PET10

1

0

High-throughput

0.460

High

647032

RPC2
DNA-directed RNA polymerase III subunit RPC2

1

0

High-throughput

0.458

High

715027

SAC1
Phosphatidylinositol-3-phosphatase SAC1

1

0

Small-scale

0.458

High

715028

ERG24
Delta(14)-sterol reductase ERG24

1

0

High-throughput

0.458

High

715030

PHO88
SRP-independent targeting protein 3

1

0

High-throughput

0.458

High

715031

RPN1
26S proteasome regulatory subunit RPN1

1

0

High-throughput

0.458

High

715035

SCS2
Vesicle-associated membrane protein-associated protein SCS2

1

0

Small-scale

0.458

High

715048

GSF2
Glucose-signaling factor 2

1

0

High-throughput

0.458

High

715049

RTN1
Reticulon-like protein 1

1

0

Small-scale

0.458

High

715054

ENV10
SRP-independent targeting protein 2

1

0

High-throughput

0.458

High

392369

HSP82
ATP-dependent molecular chaperone HSP82

1

1

High-throughput

0.437

High

670426

SIS1
Protein SIS1

1

1

High-throughput

0.437

High

544081

SSB1
Ribosome-associated molecular chaperone SSB1

1

2

High-throughput

0.407

High

715036

SSB2
Ribosome-associated molecular chaperone SSB2

1

2

High-throughput

0.407

High

506365

NFT1
ABC transporter NFT1

1

0

High-throughput

0.282

High

715041

PDR10
ATP-dependent permease PDR10

1

0

High-throughput

0.282

High

558621

CAF20
Cap-associated protein CAF20

1

0

High-throughput

0.249

Low

706418

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.249

Low

715025

HS104
Heat shock protein 104

1

0

High-throughput

0.249

Low

715032

RPN10
26S proteasome regulatory subunit RPN10

1

0

High-throughput

0.249

Low

715033

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low

715040

VATG
V-type proton ATPase subunit G

1

0

High-throughput

0.249

Low

715044

PESC
Pescadillo homolog

1

0

High-throughput

0.249

Low

715045

CUZ1
CDC48-associated ubiquitin-like/zinc finger protein 1

1

0

Small-scale

0.249

Low

715047

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.249

Low

715050

AP3D
AP-3 complex subunit delta

1

0

High-throughput

0.249

Low

715051

SIZ2
E3 SUMO-protein ligase SIZ2

1

0

High-throughput

0.249

Low

715052

DBP10
ATP-dependent RNA helicase DBP10

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025