Protein: NSMA2
Sphingomyelin phosphodiesterase 3 (EC 3.1.4.12) (Neutral sphingomyelinase 2) (nSMase-2) (nSMase2) (Neutral sphingomyelinase II)

Gene: NSMA2, SMPD3
Organism: Homo sapiens
Interactions: 34
UniProt ID: Q9NY59

Gene Ontology (top 5):
GO:0000137 - Golgi cis cisterna
GO:0000139 - Golgi membrane
GO:0001786 - phosphatidylserine binding
GO:0001958 - endochondral ossification
GO:0002244 - hematopoietic progenitor cell differentiation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

322067

ENDD1
Endonuclease domain-containing 1 protein

2

0

High-throughput

0.602

High

403233

APOB
Apolipoprotein B-100

2

0

High-throughput

0.602

High

690408

STOM
Stomatin

2

0

High-throughput

0.602

High

1041327

CAV1
Caveolin-1

2

0

High-throughput

0.602

High

1062409

PP2BA
Protein phosphatase 3 catalytic subunit alpha

2

0

High-throughput

0.602

High

733448

CCR1
C-C chemokine receptor type 1

1

0

High-throughput

0.513

High

943139

STX17
Syntaxin-17

1

0

High-throughput

0.513

High

1371977

VPP1
V-type proton ATPase 116 kDa subunit a 1

1

0

High-throughput

0.513

High

993001

RACK1
Small ribosomal subunit protein RACK1

1

0

Small-scale

0.493

High

378193

TNFA
Tumor necrosis factor

1

0

Small-scale

0.479

High

998877

H31
Histone H3.1

1

0

High-throughput

0.458

High

248421

GDF9
Growth/differentiation factor 9

1

0

High-throughput

0.438

High

558447

XRCC6
X-ray repair cross-complementing protein 6

1

0

High-throughput

0.438

High

1139856

SETB1
Histone-lysine N-methyltransferase SETDB1

1

0

High-throughput

0.438

High

1217214

RIF1
Telomere-associated protein RIF1

1

0

High-throughput

0.438

High

1272577

CSN6
COP9 signalosome complex subunit 6

1

0

High-throughput

0.438

High

1119333

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

0

High-throughput

0.426

High

989927

CANB1
Calcineurin subunit B type 1

2

0

High-throughput

0.328

High

1288071

TM135
Transmembrane protein 135

2

0

High-throughput

0.328

High

285498

EED
Polycomb protein EED

1

0

Small-scale

0.299

High

325358

OR2A4
Olfactory receptor 2A4

1

0

High-throughput

0.279

Low

773999

SOAT1
Sterol O-acyltransferase 1

1

0

High-throughput

0.279

Low

1055637

GABPA
GA-binding protein alpha chain

1

0

High-throughput

0.279

Low

1180076

PWP3A
PWWP domain-containing DNA repair factor 3A

1

0

High-throughput

0.279

Low

1361370

BRI3B
BRI3-binding protein

1

0

High-throughput

0.279

Low

1448157

ST7
Suppressor of tumorigenicity 7 protein

1

0

High-throughput

0.279

Low

1449685

TB22B
TBC1 domain family member 22B

1

0

High-throughput

0.279

Low

106743

APRIO
Alternative prion protein

1

0

High-throughput

0.249

Low

947066

DSCR9
Down syndrome critical region protein 9

1

0

High-throughput

0.238

Low

1123236

DPYL1
Dihydropyrimidinase-related protein 1

1

0

High-throughput

0.238

Low

1209167

RBM48
RNA-binding protein 48

1

0

High-throughput

0.238

Low

1383633

VOPP1
WW domain binding protein VOPP1

1

0

High-throughput

0.238

Low

1452238

MED31
Mediator of RNA polymerase II transcription subunit 31

1

0

High-throughput

0.238

Low

1452239

PKHM1
Pleckstrin homology domain-containing family M member 1

1

0

High-throughput

0.238

Low


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Last updated: 11Aug2025