Protein: ENDD1
Endonuclease domain-containing 1 protein (EC 3.1.30.-)

Gene: ENDD1, ENDOD1
Organism: Homo sapiens
Interactions: 98
UniProt ID: O94919

Gene Ontology (top 5):
GO:0003676 - nucleic acid binding
GO:0004519 - endonuclease activity
GO:0005576 - extracellular region
GO:0005829 - cytosol
GO:0016020 - membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

321992

LYPD3
Ly6/PLAUR domain-containing protein 3

4

0

High-throughput

0.661

High

321993

NPT2B
Sodium-dependent phosphate transport protein 2B

4

0

High-throughput

0.658

High

158539

CTDS2
Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2

3

0

High-throughput

0.638

High

321996

CYB5
Cytochrome b5

3

0

High-throughput

0.634

High

322076

5MP1
eIF5-mimic protein 1

3

0

High-throughput

0.634

High

322042

FNDC5
Fibronectin type III domain-containing protein 5

2

1

High-throughput

0.628

High

322001

DPEP1
Dipeptidase 1

2

0

High-throughput

0.602

High

322020

I13R2
Interleukin-13 receptor subunit alpha-2

2

0

High-throughput

0.602

High

322046

SPP2B
Signal peptide peptidase-like 2B

2

0

High-throughput

0.602

High

322067

NSMA2
Sphingomyelin phosphodiesterase 3

2

0

High-throughput

0.602

High

321999

HS90B
Heat shock protein HSP 90-beta

2

2

High-throughput

0.584

High

322013

VISL1
Visinin-like protein 1

2

0

High-throughput

0.580

High

322022

DHC24
Delta(24)-sterol reductase

2

0

High-throughput

0.576

High

322048

SSMM1
Serine-rich single-pass membrane protein 1

2

0

High-throughput

0.576

High

322056

TMM43
Transmembrane protein 43

2

0

High-throughput

0.576

High

322064

PLCC
1-acyl-sn-glycerol-3-phosphate acyltransferase gamma

2

0

High-throughput

0.576

High

322012

CAV3
Caveolin-3

2

1

High-throughput

0.574

High

255946

S19A2
Thiamine transporter 1

2

0

High-throughput

0.563

High

228531

STRN
Striatin

1

2

High-throughput

0.536

High

322017

CAV1
Caveolin-1

1

1

High-throughput

0.536

High

322061

REEP1
Receptor expression-enhancing protein 1

1

1

High-throughput

0.536

High

49723

TMM72
Transmembrane protein 72

1

0

High-throughput

0.513

High

64929

ARRD5
Arrestin domain-containing protein 5

1

0

High-throughput

0.513

High

141806

ACKR2
Atypical chemokine receptor 2

1

0

High-throughput

0.513

High

321994

STR3N
STARD3 N-terminal-like protein

1

0

High-throughput

0.513

High

322006

STOM
Stomatin

1

0

High-throughput

0.513

High

322007

HMOX2
Heme oxygenase 2

1

0

High-throughput

0.513

High

322008

COPB2
Coatomer subunit beta'

1

0

High-throughput

0.513

High

322024

STRP1
Striatin-interacting protein 1

1

0

High-throughput

0.513

High

322025

ULBP6
UL16-binding protein 6

1

0

High-throughput

0.513

High

322028

LTOR1
Ragulator complex protein LAMTOR1

1

0

High-throughput

0.513

High

322035

KI21A
Kinesin-like protein KIF21A

1

0

High-throughput

0.513

High

322054

SEC62
Translocation protein SEC62

1

0

High-throughput

0.513

High

322062

RTN4
Reticulon-4

1

0

High-throughput

0.513

High

322065

CT141
Uncharacterized protein C20orf141

1

0

High-throughput

0.513

High

322068

VAPA
Vesicle-associated membrane protein-associated protein A

1

0

High-throughput

0.513

High

322071

TSN16
Tetraspanin-16

1

0

High-throughput

0.513

High

322074

GOT1B
Vesicle transport protein GOT1B

1

0

High-throughput

0.513

High

165877

FFAR1
Free fatty acid receptor 1

1

1

High-throughput

0.489

High

322019

STRN3
Striatin-3

1

3

High-throughput

0.489

High

322036

GP141
Probable G-protein coupled receptor 141

1

1

High-throughput

0.489

High

322044

MFSD8
Major facilitator superfamily domain-containing protein 8

1

1

High-throughput

0.489

High

322055

REEP2
Receptor expression-enhancing protein 2

1

1

High-throughput

0.489

High

321998

HS90A
Heat shock protein HSP 90-alpha

1

2

High-throughput

0.479

High

322000

ENPL
Endoplasmin

1

2

High-throughput

0.479

High

322027

A16L1
Autophagy-related protein 16-1

1

1

High-throughput

0.479

High

321997

RASH
GTPase HRas

1

0

High-throughput

0.458

High

322010

SOX2
Transcription factor SOX-2

1

0

High-throughput

0.458

High

322018

KMT2A
Histone-lysine N-methyltransferase 2A

1

0

High-throughput

0.458

High

322021

MFS10
Major facilitator superfamily domain-containing protein 10

1

2

High-throughput

0.445

High

322023

TM241
UDP-N-acetylglucosamine transporter TMEM241

1

1

High-throughput

0.445

High

322045

S35B2
Adenosine 3'-phospho 5'-phosphosulfate transporter 1

1

2

High-throughput

0.445

High

322057

RNF26
E3 ubiquitin-protein ligase RNF26

1

1

High-throughput

0.437

High

321991

STBD1
Starch-binding domain-containing protein 1

1

0

High-throughput

0.426

High

321995

MOT3
Monocarboxylate transporter 3

1

0

High-throughput

0.426

High

322002

HXK1
Hexokinase-1

1

0

High-throughput

0.426

High

322011

TERA
Transitional endoplasmic reticulum ATPase

1

0

High-throughput

0.426

High

322029

MFSD5
Molybdate-anion transporter

1

0

High-throughput

0.426

High

322037

S35E3
Solute carrier family 35 member E3

1

0

High-throughput

0.426

High

322041

S35F3
Solute carrier family 35 member F3

1

0

High-throughput

0.426

High

322047

GTR12
Solute carrier family 2, facilitated glucose transporter member 12

1

0

High-throughput

0.426

High

322049

RFFL
E3 ubiquitin-protein ligase rififylin

1

0

High-throughput

0.426

High

322052

FAF2
FAS-associated factor 2

1

0

High-throughput

0.426

High

322058

UBXN6
UBX domain-containing protein 6

1

0

High-throughput

0.426

High

322075

FLVC1
Choline/ethanolamine transporter FLVCR1

1

0

High-throughput

0.426

High

322015

S35B1
Solute carrier family 35 member B1

1

1

High-throughput

0.407

High

322034

S35D2
Nucleotide sugar transporter SLC35D2

1

1

High-throughput

0.407

High

322063

S35C2
Solute carrier family 35 member C2

1

1

High-throughput

0.407

High

322059

YIPF3
Protein YIPF3

2

0

High-throughput

0.328

High

322031

T184A
Transmembrane protein 184A

2

0

High-throughput

0.313

High

164887

TR10C
Tumor necrosis factor receptor superfamily member 10C

1

0

High-throughput

0.279

Low

184091

RER1
Protein RER1

1

0

High-throughput

0.279

Low

190540

COPT2
Protein SLC31A2

1

0

High-throughput

0.279

Low

322003

C5AR1
C5a anaphylatoxin chemotactic receptor 1

1

0

High-throughput

0.279

Low

322004

EDNRA
Endothelin-1 receptor

1

0

High-throughput

0.279

Low

322005

NK1R
Substance-P receptor

1

0

High-throughput

0.279

Low

322009

P2RY2
P2Y purinoceptor 2

1

0

High-throughput

0.279

Low

322016

COG7
Conserved oligomeric Golgi complex subunit 7

1

0

High-throughput

0.279

Low

322033

PKHM3
Pleckstrin homology domain-containing family M member 3

1

0

High-throughput

0.279

Low

322040

NKAI4
Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 4

1

0

High-throughput

0.279

Low

322043

S43A3
Equilibrative nucleobase transporter 1

1

0

High-throughput

0.279

Low

322051

LDAF1
Lipid droplet assembly factor 1

1

0

High-throughput

0.279

Low

322053

BSCL2
Seipin

1

0

High-throughput

0.279

Low

322069

SUN2
SUN domain-containing protein 2

1

0

High-throughput

0.279

Low

104998

APRIO
Alternative prion protein

1

0

High-throughput

0.249

Low

217642

TGON2
Trans-Golgi network integral membrane protein 2

1

0

High-throughput

0.249

Low

322014

RNF4
E3 ubiquitin-protein ligase RNF4

1

0

High-throughput

0.249

Low

322030

LMBRL
Protein LMBR1L

1

0

High-throughput

0.249

Low

322032

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

322038

MARH3
E3 ubiquitin-protein ligase MARCHF3

1

0

High-throughput

0.249

Low

322060

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.249

Low

322066

T106B
Transmembrane protein 106B

1

0

High-throughput

0.249

Low

322070

RALY
RNA-binding protein Raly

1

0

High-throughput

0.249

Low

322026

ANR22
Ankyrin repeat domain-containing protein 22

1

0

High-throughput

0.232

Low

322039

S22A9
Organic anion transporter 7

1

0

High-throughput

0.232

Low

322050

SL9A6
Sodium/hydrogen exchanger 6

1

0

High-throughput

0.232

Low

322072

S35A3
UDP-N-acetylglucosamine transporter

1

0

High-throughput

0.232

Low

322073

S27A5
Long-chain fatty acid transport protein 5

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025