Protein: CANB1
Calcineurin subunit B type 1 (Protein phosphatase 2B regulatory subunit 1) (Protein phosphatase 3 regulatory subunit B alpha isoform 1)

Gene: CANB1, PPP3R1
Organism: Homo sapiens
Interactions: 75
UniProt ID: P63098

Gene Ontology (top 5):
GO:0001569 - branching involved in blood vessel morphogenesis
GO:0001837 - epithelial to mesenchymal transition
GO:0004723 - calcium-dependent protein serine/threonine phosphatase activity
GO:0005509 - calcium ion binding
GO:0005516 - calmodulin binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

989897

PP2BA
Protein phosphatase 3 catalytic subunit alpha

17

20

Small-scale

0.988

High

873453

PP2BC
Serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform

7

20

High-throughput

0.964

High

923656

RCAN1
Calcipressin-1

4

7

High-throughput

0.700

High

593830

PP2BB
Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform

1

20

High-throughput

0.691

High

891104

GSK3A
Glycogen synthase kinase-3 alpha

1

16

High-throughput

0.691

High

989901

IQCB1
IQ calmodulin-binding motif-containing protein 1

1

3

High-throughput

0.691

High

539155

ODPB
Pyruvate dehydrogenase E1 component subunit beta, mitochondrial

3

1

High-throughput

0.667

High

989900

RCAN2
Calcipressin-2

3

7

High-throughput

0.667

High

989930

RCAN3
Calcipressin-3

3

7

High-throughput

0.667

High

989924

CABP5
Calcium-binding protein 5

1

15

Small-scale

0.647

High

989925

CABP2
Calcium-binding protein 2

1

19

Small-scale

0.647

High

989928

CABP1
Calcium-binding protein 1

1

19

Small-scale

0.647

High

989918

PBIR1
PPP2R1A-PPP2R2A-interacting phosphatase regulator 1

3

0

High-throughput

0.638

High

340864

NFAC1
Nuclear factor of activated T-cells, cytoplasmic 1

2

3

High-throughput

0.628

High

989906

CRTC2
CREB-regulated transcription coactivator 2

2

1

High-throughput

0.628

High

989910

RHG22
Rho GTPase-activating protein 22

2

6

High-throughput

0.628

High

556911

MYH7
Myosin-7

1

1

High-throughput

0.618

High

989921

M3K5
Mitogen-activated protein kinase kinase kinase 5

1

12

Small-scale

0.618

High

553394

FCG2A
Low affinity immunoglobulin gamma Fc region receptor II-a

3

1

High-throughput

0.609

High

989912

T200A
Transmembrane protein 200A

3

1

High-throughput

0.604

High

989905

DGUOK
Deoxyguanosine kinase, mitochondrial

2

0

High-throughput

0.602

High

989929

NUFP1
FMR1-interacting protein NUFIP1

2

0

High-throughput

0.602

High

516328

CALM1
Calmodulin-1

1

9

High-throughput

0.575

High

516401

CALM2
Calmodulin-2

1

9

High-throughput

0.575

High

516500

CALM3
Calmodulin-3

1

9

High-throughput

0.575

High

989902

CNN3
Calponin-3

1

9

High-throughput

0.575

High

165309

PSA7
Proteasome subunit alpha type-7

1

1

Small-scale

0.552

High

989926

PICK1
PRKCA-binding protein

1

1

Small-scale

0.552

High

298346

DNJC8
DnaJ homolog subfamily C member 8

1

2

High-throughput

0.536

High

989895

HXC5
Homeobox protein Hox-C5

1

2

High-throughput

0.536

High

239931

SOX15
Transcription factor SOX-15

1

1

High-throughput

0.515

High

124303

HAX1
HCLS1-associated protein X-1

1

0

High-throughput

0.513

High

135153

IF2B3
Insulin-like growth factor 2 mRNA-binding protein 3

1

0

High-throughput

0.513

High

437485

CASB
Beta-casein

1

0

High-throughput

0.513

High

897627

RASF2
Ras association domain-containing protein 2

1

0

High-throughput

0.513

High

906865

GPM6A
Neuronal membrane glycoprotein M6-a

1

0

High-throughput

0.513

High

989913

TENS4
Tensin-4

1

0

High-throughput

0.513

High

989915

TRI41
E3 ubiquitin-protein ligase TRIM41

1

0

High-throughput

0.513

High

989920

SPT33
Spermatogenesis-associated protein 33

1

0

High-throughput

0.513

High

522071

BCL2
Apoptosis regulator Bcl-2

1

1

Small-scale

0.501

High

989909

KCNKI
Potassium channel subfamily K member 18

1

1

High-throughput

0.489

High

371703

MYC
Myc proto-oncogene protein

1

0

Small-scale

0.480

High

832689

BCL6
B-cell lymphoma 6 protein

1

1

Small-scale

0.479

High

989898

PDE4D
3',5'-cyclic-AMP phosphodiesterase 4D

1

1

Small-scale

0.479

High

989899

TRAF3
TNF receptor-associated factor 3

1

2

Small-scale

0.479

High

989922

TINF2
TERF1-interacting nuclear factor 2

1

1

High-throughput

0.479

High

136869

AGRIN
Agrin [Cleaved into: Agrin N-terminal 110 kDa subunit; Agrin C-terminal 110 kDa subunit; Agrin C-terminal 90 kDa fragment

1

0

High-throughput

0.458

High

413578

P53
Cellular tumor antigen p53

1

0

High-throughput

0.458

High

989911

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

0

Small-scale

0.458

High

529572

TAU
Microtubule-associated protein tau

1

8

High-throughput

0.445

High

929886

UBP14
Ubiquitin carboxyl-terminal hydrolase 14

1

2

Small-scale

0.445

High

986325

PPIA
Peptidyl-prolyl cis-trans isomerase A

1

4

Small-scale

0.445

High

890643

RGS3
Regulator of G-protein signaling 3

1

0

High-throughput

0.426

High

989908

PSRC1
Proline/serine-rich coiled-coil protein 1

1

0

High-throughput

0.426

High

854522

S15A1
Solute carrier family 15 member 1

1

7

High-throughput

0.407

High

989907

CSAG1
Chondrosarcoma-associated gene 1 protein

1

2

High-throughput

0.407

High

989933

CSAG2
Chondrosarcoma-associated gene 2/3 protein

1

2

High-throughput

0.407

High

62109

KLRG2
Killer cell lectin-like receptor subfamily G member 2

3

0

High-throughput

0.345

High

989917

ESS2
Splicing factor ESS-2 homolog

3

0

High-throughput

0.345

High

665920

IBP6
Insulin-like growth factor-binding protein 6

2

0

High-throughput

0.328

High

947975

DEF1
Neutrophil defensin 1

2

0

High-throughput

0.328

High

989896

CDR2
Cerebellar degeneration-related protein 2

2

0

High-throughput

0.328

High

989914

SRBD1
S1 RNA-binding domain-containing protein 1

2

0

High-throughput

0.328

High

989927

NSMA2
Sphingomyelin phosphodiesterase 3

2

0

High-throughput

0.328

High

989903

ACHA6
Neuronal acetylcholine receptor subunit alpha-6

1

0

High-throughput

0.292

High

989932

NP1L2
Nucleosome assembly protein 1-like 2

1

0

High-throughput

0.282

High

280912

HYPM
Huntingtin-interacting protein M

1

0

High-throughput

0.279

Low

504686

F163B
Protein FAM163B

1

0

High-throughput

0.279

Low

989894

PRR3
Proline-rich protein 3

1

0

High-throughput

0.279

Low

989916

PMEPA
Protein TMEPAI

1

0

High-throughput

0.279

Low

989923

LIME1
Lck-interacting transmembrane adapter 1

1

0

High-throughput

0.279

Low

989931

TMCC3
Transmembrane and coiled-coil domain protein 3

1

0

High-throughput

0.279

Low

989904

ADIPO
Adiponectin

1

0

High-throughput

0.232

Low

989919

F167A
Protein FAM167A

1

0

High-throughput

0.232

Low

989934

S4A7
Sodium bicarbonate cotransporter 3

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025