Protein: BLMH
Bleomycin hydrolase (BH) (BLM hydrolase) (BMH) (EC 3.4.22.40)

Gene: BLMH
Organism: Homo sapiens
Interactions: 135
UniProt ID: Q13867

Gene Ontology (top 5):
GO:0000209 - protein polyubiquitination
GO:0004177 - aminopeptidase activity
GO:0004180 - carboxypeptidase activity
GO:0004197 - cysteine-type endopeptidase activity
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1118209

BLMH
Bleomycin hydrolase

6

4

High-throughput

0.946

High

1118246

NUD12
NAD-capped RNA hydrolase NUDT12

6

1

High-throughput

0.740

High

422080

A4
Amyloid-beta precursor protein

3

2

Small-scale

0.672

High

1118241

TRI47
E3 ubiquitin-protein ligase TRIM47

2

2

High-throughput

0.606

High

1118271

TNPO3
Transportin-3

2

1

High-throughput

0.606

High

1118240

NTAQ1
Protein N-terminal glutamine amidohydrolase

2

0

High-throughput

0.601

High

830706

CCNF
Cyclin-F

2

1

High-throughput

0.584

High

164573

TNPO2
Transportin-2

2

0

High-throughput

0.580

High

333820

6PGL
6-phosphogluconolactonase

2

0

High-throughput

0.580

High

1118262

NXF1
Nuclear RNA export factor 1

2

0

High-throughput

0.580

High

1118214

TNIP1
TNFAIP3-interacting protein 1

2

0

High-throughput

0.559

High

993559

UBC9
SUMO-conjugating enzyme UBC9

1

0

Small-scale

0.549

High

463089

YES
Tyrosine-protein kinase Yes

1

1

High-throughput

0.536

High

463512

LYN
Tyrosine-protein kinase Lyn

1

1

High-throughput

0.536

High

518599

RAP2A
Ras-related protein Rap-2a

1

1

High-throughput

0.536

High

639128

SYT1
Synaptotagmin-1

1

1

High-throughput

0.536

High

856679

BAG6
Large proline-rich protein BAG6

1

1

High-throughput

0.536

High

1118234

CSN5
COP9 signalosome complex subunit 5

1

1

High-throughput

0.536

High

299545

TRIO
Triple functional domain protein

1

0

High-throughput

0.518

High

528918

CP2C8
Cytochrome P450 2C8

1

0

High-throughput

0.518

High

1118231

KBTB7
Kelch repeat and BTB domain-containing protein 7

1

0

High-throughput

0.518

High

1118245

ECSIT
Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial

1

0

High-throughput

0.518

High

1118250

RNF32
RING finger protein 32

1

0

High-throughput

0.518

High

1118265

MAST1
Microtubule-associated serine/threonine-protein kinase 1

1

0

High-throughput

0.518

High

407624

S100B
Protein S100-B

1

2

High-throughput

0.515

High

712864

CASP1
Caspase-1

1

1

High-throughput

0.515

High

849165

KSYK
Tyrosine-protein kinase SYK

1

1

High-throughput

0.515

High

1055312

APLP2
Amyloid beta precursor like protein 2

1

1

High-throughput

0.515

High

238896

DHX16
Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16

1

0

High-throughput

0.513

High

250602

HNRPQ
Heterogeneous nuclear ribonucleoprotein Q

1

0

High-throughput

0.513

High

563739

CFTR
Cystic fibrosis transmembrane conductance regulator

1

0

High-throughput

0.513

High

853677

MK08
Mitogen-activated protein kinase 8

1

0

High-throughput

0.513

High

861604

NEDD4
E3 ubiquitin-protein ligase NEDD4

1

0

High-throughput

0.513

High

922251

LIMK1
LIM domain kinase 1

1

0

High-throughput

0.513

High

1100762

G3BP1
Ras GTPase-activating protein-binding protein 1

1

0

High-throughput

0.513

High

1115183

CUL4B
Cullin-4B

1

0

High-throughput

0.513

High

1118210

IDI1
Isopentenyl-diphosphate Delta-isomerase 1

1

0

High-throughput

0.513

High

1118211

HNRPD
Heterogeneous nuclear ribonucleoprotein D0

1

0

High-throughput

0.513

High

1118213

FL2D
Pre-mRNA-splicing regulator WTAP

1

0

High-throughput

0.513

High

1118215

PMVK
Phosphomevalonate kinase

1

0

High-throughput

0.513

High

1118217

MARE1
Microtubule-associated protein RP/EB family member 1

1

0

High-throughput

0.513

High

1118218

TKFC
Triokinase/FMN cyclase

1

0

High-throughput

0.513

High

1118224

JADE1
Protein Jade-1

1

0

High-throughput

0.513

High

1118228

AROS
Active regulator of SIRT1

1

0

High-throughput

0.513

High

1118229

SETD7
Histone-lysine N-methyltransferase SETD7

1

0

High-throughput

0.513

High

1118235

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

0

High-throughput

0.513

High

1118236

TP4A1
Protein tyrosine phosphatase type IVA 1

1

0

High-throughput

0.513

High

1118243

SORT
Sortilin

1

0

High-throughput

0.513

High

1118244

C10
Protein C10

1

0

High-throughput

0.513

High

1118254

MET14
N(6)-adenosine-methyltransferase non-catalytic subunit METTL14

1

0

High-throughput

0.513

High

1118257

ANLN
Anillin

1

0

High-throughput

0.513

High

868514

RL29
Large ribosomal subunit protein eL29

1

0

Small-scale

0.504

High

985653

RL11
Large ribosomal subunit protein uL5

1

0

Small-scale

0.504

High

1060871

LRP1
Prolow-density lipoprotein receptor-related protein 1

1

0

High-throughput

0.493

High

1118247

UT14A
U3 small nucleolar RNA-associated protein 14 homolog A

1

0

High-throughput

0.493

High

1118260

VPS29
Vacuolar protein sorting-associated protein 29

1

0

High-throughput

0.493

High

1118239

SGTB
Small glutamine-rich tetratricopeptide repeat-containing protein beta

1

1

High-throughput

0.489

High

193573

PDPK1
3-phosphoinositide-dependent protein kinase 1

1

0

High-throughput

0.486

High

955149

CDC42
Cell division control protein 42 homolog

1

0

High-throughput

0.480

High

315574

RECQ4
ATP-dependent DNA helicase Q4

1

1

High-throughput

0.479

High

342865

HERC2
E3 ubiquitin-protein ligase HERC2

1

1

High-throughput

0.479

High

456725

ANXA2
Annexin A2

1

1

High-throughput

0.479

High

606744

CEBPB
CCAAT/enhancer-binding protein beta

1

1

High-throughput

0.479

High

635588

FILA
Filaggrin

1

1

High-throughput

0.479

High

713378

SPB3
Serpin B3

1

2

High-throughput

0.479

High

714105

PML
Protein PML

1

2

High-throughput

0.479

High

729554

CASPE
Caspase-14

1

1

High-throughput

0.479

High

730575

1433S
14-3-3 protein sigma

1

1

High-throughput

0.479

High

787642

SPB5
Serpin B5

1

2

High-throughput

0.479

High

990204

1433Z
14-3-3 protein zeta/delta

1

1

Small-scale

0.479

High

1036724

DSG1
Desmoglein-1

1

2

High-throughput

0.479

High

1064426

DSC1
Desmocollin-1

1

1

High-throughput

0.479

High

1118014

DX39B
Spliceosome RNA helicase DDX39B

1

1

High-throughput

0.479

High

1118212

TRI25
E3 ubiquitin/ISG15 ligase TRIM25

1

2

High-throughput

0.479

High

1118225

TRI67
Tripartite motif-containing protein 67

1

2

High-throughput

0.479

High

1118242

SPB12
Serpin B12

1

2

High-throughput

0.479

High

1118248

FACD2
Fanconi anemia group D2 protein

1

1

High-throughput

0.479

High

1118249

DDX24
ATP-dependent RNA helicase DDX24

1

1

High-throughput

0.479

High

1118255

S10AE
Protein S100-A14

1

2

High-throughput

0.479

High

1118264

UBQL2
Ubiquilin-2

1

1

High-throughput

0.479

High

1118272

AP1M2
AP-1 complex subunit mu-2

1

0

High-throughput

0.460

High

141477

DDX3X
ATP-dependent RNA helicase DDX3X

1

0

Small-scale

0.458

High

241636

PRKN
E3 ubiquitin-protein ligase parkin

1

0

High-throughput

0.458

High

371982

MYC
Myc proto-oncogene protein

1

0

High-throughput

0.458

High

374588

RASH
GTPase HRas

1

0

High-throughput

0.458

High

413802

P53
Cellular tumor antigen p53

1

0

Small-scale

0.458

High

423651

ARGI1
Arginase-1

1

0

High-throughput

0.458

High

456232

CATD
Cathepsin D

1

0

High-throughput

0.458

High

457864

INVO
Involucrin

1

0

High-throughput

0.458

High

537130

HSP7C
Heat shock cognate 71 kDa protein

1

0

High-throughput

0.458

High

587656

DESP
Desmoplakin

1

0

High-throughput

0.458

High

588657

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.458

High

623337

RO52
E3 ubiquitin-protein ligase TRIM21

1

0

High-throughput

0.458

High

695418

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

888048

MCM2
DNA replication licensing factor MCM2

1

0

High-throughput

0.458

High

907420

UBP11
Ubiquitin carboxyl-terminal hydrolase 11

1

0

High-throughput

0.458

High

1062232

TGM3
Protein-glutamine gamma-glutamyltransferase E

1

0

High-throughput

0.458

High

1106841

BIRC3
Baculoviral IAP repeat-containing protein 3

1

0

High-throughput

0.458

High

1117938

PKP1
Plakophilin-1

1

0

High-throughput

0.458

High

1118220

KPRP
Keratinocyte proline-rich protein

1

0

High-throughput

0.458

High

1118232

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

0

High-throughput

0.458

High

1118233

RBP56
TATA-binding protein-associated factor 2N

1

0

High-throughput

0.458

High

1118237

ZUP1
Zinc finger-containing ubiquitin peptidase 1

1

0

Small-scale

0.458

High

1118238

CHM4C
Charged multivesicular body protein 4c

1

0

High-throughput

0.458

High

1118251

RNF38
E3 ubiquitin-protein ligase RNF38

1

0

Small-scale

0.458

High

1118252

CCDC8
Coiled-coil domain-containing protein 8

1

0

High-throughput

0.458

High

1118253

AKTIP
AKT-interacting protein

1

0

Small-scale

0.458

High

1118256

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

0

High-throughput

0.458

High

1118258

PD1L1
Programmed cell death 1 ligand 1

1

0

High-throughput

0.458

High

1118259

CALL5
Calmodulin-like protein 5

1

0

High-throughput

0.458

High

1118263

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

1118266

ZBTB1
Zinc finger and BTB domain-containing protein 1

1

0

Small-scale

0.458

High

1118268

LOXL2
Lysyl oxidase homolog 2

1

0

High-throughput

0.458

High

1118269

WIPI2
WD repeat domain phosphoinositide-interacting protein 2

1

0

High-throughput

0.458

High

429859

JUN
Transcription factor Jun

1

1

High-throughput

0.445

High

626222

NFKB1
Nuclear factor NF-kappa-B p105 subunit

1

1

High-throughput

0.445

High

952158

GBRL2
Gamma-aminobutyric acid receptor-associated protein-like 2

1

1

High-throughput

0.445

High

529769

TAU
Microtubule-associated protein tau

1

0

High-throughput

0.426

High

948820

CD81
CD81 antigen

1

0

High-throughput

0.426

High

1118219

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

0

High-throughput

0.426

High

1118222

A16L1
Autophagy-related protein 16-1

1

0

High-throughput

0.426

High

886838

CEBPA
CCAAT/enhancer-binding protein alpha

1

1

High-throughput

0.408

High

262175

KERA
Keratocan

2

0

High-throughput

0.328

High

1118223

ATLA3
Atlastin-3

1

0

High-throughput

0.279

Low

1118226

UBP53
Ubiquitin carboxyl-terminal hydrolase 53

1

0

High-throughput

0.279

Low

1118267

FCF1
rRNA-processing protein FCF1 homolog

1

0

High-throughput

0.279

Low

1118270

PCDBF
Protocadherin beta-15

1

0

High-throughput

0.279

Low

1118261

DBF4A
Protein DBF4 homolog A

1

0

High-throughput

0.268

Low

105903

APRIO
Alternative prion protein

1

0

High-throughput

0.249

Low

768149

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

1118216

CDSN
Corneodesmosin

1

0

High-throughput

0.249

Low

1118221

KPLCE
Protein KPLCE

1

0

High-throughput

0.249

Low

1118227

ZCH18
Zinc finger CCCH domain-containing protein 18

1

0

High-throughput

0.249

Low

1118230

POF1B
Protein POF1B

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025