Protein: EXOC6
Exocyst complex component 6 (Exocyst complex component Sec15A) (SEC15-like protein 1)

Gene: EXOC6
Organism: Homo sapiens
Interactions: 99
UniProt ID: Q8TAG9

Gene Ontology (top 5):
GO:0000145 - exocyst
GO:0000281 - mitotic cytokinesis
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0006886 - intracellular protein transport

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

137254

EXOC5
Exocyst complex component 5

5

3

High-throughput

0.721

High

1347236

EXOC4
Exocyst complex component 4

4

2

Small-scale

0.697

High

1347251

EXOC1
Exocyst complex component 1

4

1

High-throughput

0.697

High

252887

EXOC3
Exocyst complex component 3

4

2

High-throughput

0.691

High

1315101

EXOC8
Exocyst complex component 8

3

3

High-throughput

0.675

High

1347241

EXOC2
Exocyst complex component 2

3

3

High-throughput

0.675

High

1347259

EXOC7
Exocyst complex component 7

3

2

High-throughput

0.675

High

1347239

DTBP1
Dysbindin

3

1

High-throughput

0.667

High

1347249

DSN1
Kinetochore-associated protein DSN1 homolog

4

0

High-throughput

0.661

High

286687

STX11
Syntaxin-11

2

3

High-throughput

0.628

High

466939

ACM4
Muscarinic acetylcholine receptor M4

2

1

High-throughput

0.628

High

699566

IL1R2
Interleukin-1 receptor type 2

2

1

High-throughput

0.628

High

771185

APJ
Apelin receptor

2

3

High-throughput

0.628

High

879808

NPY2R
Neuropeptide Y receptor type 2

2

1

High-throughput

0.628

High

982105

RAP1A
Ras-related protein Rap-1A

2

3

High-throughput

0.628

High

262271

SCN2B
Sodium channel regulatory subunit beta-2

2

3

High-throughput

0.611

High

955974

RAB8A
Ras-related protein Rab-8A

2

2

Small-scale

0.611

High

1347258

CAH14
Carbonic anhydrase 14

2

1

High-throughput

0.611

High

1347261

EXC6B
Exocyst complex component 6B

2

2

High-throughput

0.611

High

749239

CD70
CD70 antigen

2

0

High-throughput

0.602

High

1217267

VPS53
Vacuolar protein sorting-associated protein 53 homolog

2

0

High-throughput

0.602

High

1347242

CAR19
Caspase recruitment domain-containing protein 19

2

0

High-throughput

0.602

High

182678

GP182
G-protein coupled receptor 182

2

5

High-throughput

0.601

High

388254

GLPA
Glycophorin-A

2

1

High-throughput

0.601

High

754072

CD80
T-lymphocyte activation antigen CD80

2

2

High-throughput

0.601

High

976435

RB11A
Ras-related protein Rab-11A

2

2

Small-scale

0.584

High

1347267

NPTN
Neuroplastin

2

0

High-throughput

0.576

High

1347233

EXOC6
Exocyst complex component 6

1

2

High-throughput

0.541

High

133284

P2Y10
Putative P2Y purinoceptor 10

1

5

High-throughput

0.536

High

406911

MAS
Proto-oncogene Mas

1

5

High-throughput

0.536

High

638477

FPR1
fMet-Leu-Phe receptor

1

5

High-throughput

0.536

High

835333

VIPR2
Vasoactive intestinal polypeptide receptor 2

1

1

High-throughput

0.536

High

956947

CXCR4
C-X-C chemokine receptor type 4

1

3

High-throughput

0.536

High

1022918

EFNB1
Ephrin-B1

1

1

High-throughput

0.536

High

1042762

PTH1R
Parathyroid hormone/parathyroid hormone-related peptide receptor

1

1

High-throughput

0.536

High

1101598

GPR17
Uracil nucleotide/cysteinyl leukotriene receptor

1

3

High-throughput

0.536

High

1347243

CML1
Chemerin-like receptor 1

1

5

High-throughput

0.536

High

1347252

C5AR2
C5a anaphylatoxin chemotactic receptor 2

1

5

High-throughput

0.536

High

422666

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.518

High

713121

NOS3
Nitric oxide synthase 3

1

0

High-throughput

0.518

High

732364

PRDX2
Peroxiredoxin-2

1

0

High-throughput

0.518

High

890754

PSN2
Presenilin-2

1

0

High-throughput

0.518

High

1347244

ECSIT
Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial

1

0

High-throughput

0.518

High

1347262

MAST1
Microtubule-associated serine/threonine-protein kinase 1

1

0

High-throughput

0.518

High

1347264

EXOS1
Exosome complex component CSL4

1

0

High-throughput

0.518

High

219984

XRCC3
DNA repair protein XRCC3

1

0

High-throughput

0.513

High

486591

TACD2
Tumor-associated calcium signal transducer 2

1

0

High-throughput

0.513

High

893510

GNAQ
Guanine nucleotide-binding protein G(q) subunit alpha

1

0

High-throughput

0.513

High

1053034

VMAT2
Synaptic vesicular amine transporter

1

0

High-throughput

0.513

High

1249818

BTNL9
Butyrophilin-like protein 9

1

0

High-throughput

0.513

High

1347246

SEM4C
Semaphorin-4C

1

0

High-throughput

0.513

High

1199340

GLE1
mRNA export factor GLE1

1

0

High-throughput

0.493

High

1279653

SPRE1
Sprouty-related, EVH1 domain-containing protein 1

1

0

High-throughput

0.493

High

1347248

F234A
Protein FAM234A

1

1

High-throughput

0.489

High

1347255

CC018
Uncharacterized protein C3orf18

1

1

High-throughput

0.489

High

189727

STX7
Syntaxin-7

1

1

High-throughput

0.479

High

363594

EGFR
Epidermal growth factor receptor

1

2

High-throughput

0.479

High

412291

NTRK1
High affinity nerve growth factor receptor

1

1

High-throughput

0.479

High

1100693

STX3
Syntaxin-3

1

3

Small-scale

0.479

High

1347237

VP33A
Vacuolar protein sorting-associated protein 33A

1

1

High-throughput

0.479

High

1347265

MYO5A
Unconventional myosin-Va

1

2

Small-scale

0.479

High

528919

CP2C8
Cytochrome P450 2C8

1

0

High-throughput

0.460

High

1347247

RNF32
RING finger protein 32

1

0

High-throughput

0.460

High

138235

PSDE
26S proteasome non-ATPase regulatory subunit 14

1

0

Small-scale

0.458

High

242349

PRKN
E3 ubiquitin-protein ligase parkin

1

0

High-throughput

0.458

High

404248

GCR
Glucocorticoid receptor

1

0

High-throughput

0.458

High

1113766

CUL3
Cullin-3

1

0

High-throughput

0.458

High

1178265

CL16A
Protein CLEC16A

1

0

High-throughput

0.458

High

1249036

LMBRL
Protein LMBR1L

1

0

High-throughput

0.458

High

1347253

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

1347263

TBC30
TBC1 domain family member 30

1

0

Small-scale

0.458

High

171522

S27A2
Long-chain fatty acid transport protein 2

1

1

High-throughput

0.445

High

683290

TNR5
Tumor necrosis factor receptor superfamily member 5

1

1

High-throughput

0.445

High

1347238

S67A1
Solute carrier family 67 member A1

1

1

High-throughput

0.445

High

1347245

S39A3
Zinc transporter ZIP3

1

1

High-throughput

0.445

High

1347250

S39A9
Zinc transporter ZIP9

1

1

High-throughput

0.445

High

1347254

XPO7
Exportin-7

1

1

High-throughput

0.437

High

1347257

MYO5B
Unconventional myosin-Vb

1

2

Small-scale

0.437

High

166355

ZNT4
Probable proton-coupled zinc antiporter SLC30A4

1

0

High-throughput

0.426

High

220611

AKA10
A-kinase anchor protein 10, mitochondrial

1

0

High-throughput

0.426

High

538788

GTR2
Solute carrier family 2, facilitated glucose transporter member 2

1

0

High-throughput

0.426

High

1347260

XCT
Cystine/glutamate transporter

1

0

High-throughput

0.426

High

50631

HACL2
2-hydroxyacyl-CoA lyase 2

1

1

High-throughput

0.407

High

1293871

VSIG1
V-set and immunoglobulin domain-containing protein 1

1

1

High-throughput

0.407

High

1330716

SIGL1
SIGLEC family-like protein 1

2

0

High-throughput

0.328

High

1347235

GCDH
Glutaryl-CoA dehydrogenase, mitochondrial

1

0

High-throughput

0.282

High

1347240

LOXL4
Lysyl oxidase homolog 4

1

0

High-throughput

0.282

High

390114

ALBU
Albumin

1

0

High-throughput

0.279

Low

1164478

MIC60
MICOS complex subunit MIC60

1

0

High-throughput

0.279

Low

1347234

F174A
Membrane protein FAM174A

1

0

High-throughput

0.279

Low

1347266

SAM50
Sorting and assembly machinery component 50 homolog

1

0

High-throughput

0.279

Low

589217

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.249

Low

696000

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.249

Low

768698

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

1256799

PLPL7
Patatin-like phospholipase domain-containing protein 7

1

0

High-throughput

0.249

Low

1276514

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.249

Low

1347256

HECD1
E3 ubiquitin-protein ligase HECTD1

1

0

High-throughput

0.249

Low

1325874

MFD4A
Major facilitator superfamily domain-containing protein 4A

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025