Protein: ITPA
Inosine triphosphate pyrophosphatase (ITPase) (Inosine triphosphatase) (EC 3.6.1.66) (Non-canonical purine NTP pyrophosphatase) (Non-standard purine NTP pyrophosphatase) (Nucleoside-triphosphate diphosphatase) (Nucleoside-triphosphate pyrophosphatase) (NTPase) (Putative oncogene protein hlc14-06-p) (XTP/dITP diphosphatase)

Gene: ITPA
Organism: Homo sapiens
Interactions: 47
UniProt ID: Q9BY32

Gene Ontology (top 5):
GO:0000166 - nucleotide binding
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006193 - ITP catabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1417717

ITPA
Inosine triphosphate pyrophosphatase

3

0

High-throughput

0.817

High

276922

VPS4B
Vacuolar protein sorting-associated protein 4B

3

0

High-throughput

0.638

High

942196

WNT4
Protein Wnt-4

3

0

High-throughput

0.638

High

1410863

FERM1
Fermitin family homolog 1

2

0

High-throughput

0.602

High

1399341

SPB11
Serpin B11

2

1

High-throughput

0.584

High

219228

LTOR5
Ragulator complex protein LAMTOR5

2

0

High-throughput

0.576

High

401430

RAF1
RAF proto-oncogene serine/threonine-protein kinase

2

0

High-throughput

0.559

High

733428

CCR1
C-C chemokine receptor type 1

1

0

High-throughput

0.513

High

1209926

PPM1L
Protein phosphatase 1L

1

0

High-throughput

0.513

High

1219229

LIPK
Lipase member K

1

0

High-throughput

0.513

High

1224897

TENS2
Tensin-2

1

0

High-throughput

0.513

High

1250721

RAD9B
Cell cycle checkpoint control protein RAD9B

1

0

High-throughput

0.513

High

1417718

MMP28
Matrix metalloproteinase-28

1

0

High-throughput

0.513

High

1417721

ENTP7
Ectonucleoside triphosphate diphosphohydrolase 7

1

0

High-throughput

0.513

High

1417722

EXD2
Exonuclease 3'-5' domain-containing protein 2

1

1

High-throughput

0.479

High

242814

PRKN
E3 ubiquitin-protein ligase parkin

1

0

High-throughput

0.458

High

363817

EGFR
Epidermal growth factor receptor

1

0

High-throughput

0.458

High

404390

GCR
Glucocorticoid receptor

1

0

High-throughput

0.458

High

831371

CCNF
Cyclin-F

1

0

High-throughput

0.458

High

930045

UBP14
Ubiquitin carboxyl-terminal hydrolase 14

1

0

High-throughput

0.458

High

971029

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.458

High

1255389

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.458

High

1339164

NUP35
Nucleoporin NUP35

1

0

High-throughput

0.458

High

1397400

CI072
Guanine nucleotide exchange factor C9orf72

1

0

High-throughput

0.458

High

1417720

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.458

High

1417723

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

1417724

TRRAP
Transformation/transcription domain-associated protein

1

0

High-throughput

0.458

High

1209616

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

0

High-throughput

0.426

High

104034

F5GYW9
Serpin family B member 11

1

1

High-throughput

0.407

High

887196

CEBPA
CCAAT/enhancer-binding protein alpha

1

0

High-throughput

0.391

High

597010

TSHR
Thyrotropin receptor

3

0

High-throughput

0.347

High

273782

ATS4
A disintegrin and metalloproteinase with thrombospondin motifs 4

2

0

High-throughput

0.328

High

387886

FIBB
Fibrinogen beta chain [Cleaved into: Fibrinopeptide B; Fibrinogen beta chain]

2

0

High-throughput

0.328

High

946362

FAM3B
Protein FAM3B

2

0

High-throughput

0.328

High

142231

CCL22
C-C motif chemokine 22

1

0

High-throughput

0.279

Low

455664

KLK3
Prostate-specific antigen

1

0

High-throughput

0.279

Low

702841

5HT2C
5-hydroxytryptamine receptor 2C

1

0

High-throughput

0.279

Low

933222

SLUR1
Secreted Ly-6/uPAR-related protein 1

1

0

High-throughput

0.279

Low

1154347

CYTM
Cystatin-M

1

0

High-throughput

0.279

Low

1181027

DB136
Defensin beta 136

1

0

High-throughput

0.279

Low

1372441

P2RX5
P2X purinoceptor 5

1

0

High-throughput

0.279

Low

1395163

HIPL1
HHIP-like protein 1

1

0

High-throughput

0.279

Low

663827

LAMA2
Laminin subunit alpha-2

1

0

High-throughput

0.249

Low

1162538

CLPP
ATP-dependent Clp protease proteolytic subunit, mitochondrial

1

0

High-throughput

0.249

Low

1417719

IFG15
Torsin-1A-interacting protein 2, isoform IFRG15

1

0

High-throughput

0.249

Low

1339457

TOIP2
Torsin-1A-interacting protein 2

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025