Protein: SL9A6
Sodium/hydrogen exchanger 6 (Na(+)/H(+) exchanger 6) (NHE-6) (Solute carrier family 9 member 6)

Gene: SL9A6, SLC9A6
Organism: Homo sapiens
Interactions: 106
UniProt ID: Q92581

Gene Ontology (top 5):
GO:0005789 - endoplasmic reticulum membrane
GO:0005886 - plasma membrane
GO:0006811 - monoatomic ion transport
GO:0015385 - sodium:proton antiporter activity
GO:0015386 - potassium:proton antiporter activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1365118

SL9A7
Sodium/hydrogen exchanger 7

3

8

High-throughput

0.855

High

582187

INGR1
Interferon gamma receptor 1

4

0

High-throughput

0.669

High

609763

LEG3
Galectin-3

3

4

High-throughput

0.667

High

1365128

FNDC4
Fibronectin type III domain-containing protein 4

3

2

High-throughput

0.667

High

906127

AL3A2
Aldehyde dehydrogenase family 3 member A2

3

2

High-throughput

0.662

High

953596

RAC3
Ras-related C3 botulinum toxin substrate 3

3

10

High-throughput

0.662

High

1332745

PMGT2
Protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2

3

1

High-throughput

0.662

High

1228765

MBLC2
Acyl-coenzyme A thioesterase MBLAC2

4

0

High-throughput

0.658

High

170901

CLGN
Calmegin

3

1

High-throughput

0.643

High

848053

AL3B1
Aldehyde dehydrogenase family 3 member B1

2

2

High-throughput

0.628

High

1334446

RELL2
RELT-like protein 2

2

2

High-throughput

0.628

High

1365133

SERC1
Serine incorporator 1

2

1

High-throughput

0.628

High

125549

LEG9
Galectin-9

3

4

High-throughput

0.609

High

127381

LEG8
Galectin-8

3

4

High-throughput

0.609

High

1365115

DJC30
DnaJ homolog subfamily C member 30, mitochondrial

3

11

High-throughput

0.604

High

1365123

FUT8
Alpha-(1,6)-fucosyltransferase

3

1

High-throughput

0.604

High

256100

S19A2
Thiamine transporter 1

2

0

High-throughput

0.602

High

1365124

S39A8
Metal cation symporter ZIP8

2

0

High-throughput

0.602

High

698959

CALX
Calnexin

2

1

High-throughput

0.601

High

885495

MA2A2
Alpha-mannosidase 2x

2

1

High-throughput

0.574

High

1308923

S22A9
Organic anion transporter 7

2

1

High-throughput

0.574

High

1365114

GLT14
Polypeptide N-acetylgalactosaminyltransferase 14

2

5

High-throughput

0.549

High

641225

FGFR2
Fibroblast growth factor receptor 2

1

4

High-throughput

0.536

High

1365120

KI2L4
Killer cell immunoglobulin-like receptor 2DL4

1

1

High-throughput

0.536

High

65454

TLCD2
TLC domain-containing protein 2

1

0

High-throughput

0.513

High

190562

COPT2
Protein SLC31A2

1

0

High-throughput

0.513

High

1153292

AAAT
Neutral amino acid transporter B(0)

1

0

High-throughput

0.513

High

1333750

TM87A
Transmembrane protein 87A

1

0

High-throughput

0.513

High

1365125

YIPF3
Protein YIPF3

1

0

High-throughput

0.513

High

1365144

SPCS1
Signal peptidase complex subunit 1

1

0

High-throughput

0.513

High

1185360

LEG9B
Galectin-9B

1

4

High-throughput

0.489

High

1293880

VSIG1
V-set and immunoglobulin domain-containing protein 1

1

2

High-throughput

0.489

High

279194

ULK1
Serine/threonine-protein kinase ULK1

1

2

Small-scale

0.479

High

280288

SC22B
Vesicle-trafficking protein SEC22b

1

2

High-throughput

0.445

High

321319

ERLN2
Erlin-2

1

6

High-throughput

0.445

High

600884

HSP76
Heat shock 70 kDa protein 6

1

4

High-throughput

0.445

High

640973

VDAC1
Non-selective voltage-gated ion channel VDAC1

1

4

High-throughput

0.445

High

675095

TNR6
Tumor necrosis factor receptor superfamily member 6

1

2

High-throughput

0.445

High

701879

ABCD3
ATP-binding cassette sub-family D member 3

1

2

High-throughput

0.445

High

951312

SC61B
Protein transport protein Sec61 subunit beta

1

1

High-throughput

0.445

High

1119228

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

1

High-throughput

0.445

High

1125579

FKBP8
Peptidyl-prolyl cis-trans isomerase FKBP8

1

1

High-throughput

0.445

High

1131479

MBTP1
Membrane-bound transcription factor site-1 protease

1

1

High-throughput

0.445

High

1199625

KLH22
Kelch-like protein 22

1

1

High-throughput

0.445

High

1209924

PPM1L
Protein phosphatase 1L

1

3

High-throughput

0.445

High

1257474

MBOA2
Membrane-bound glycerophospholipid O-acyltransferase 2

1

2

High-throughput

0.445

High

1275381

ERMP1
Endoplasmic reticulum metallopeptidase 1

1

1

High-throughput

0.445

High

1330333

EMC1
ER membrane protein complex subunit 1

1

3

High-throughput

0.445

High

1333434

XXLT1
Xyloside xylosyltransferase 1

1

1

High-throughput

0.445

High

1365111

LPAR1
Lysophosphatidic acid receptor 1

1

3

High-throughput

0.445

High

1365116

MBOA7
Membrane-bound acylglycerophosphatidylinositol O-acyltransferase MBOAT7

1

2

High-throughput

0.445

High

1365119

SEC62
Translocation protein SEC62

1

1

High-throughput

0.445

High

1365122

TMUB1
Transmembrane and ubiquitin-like domain-containing protein 1

1

1

High-throughput

0.445

High

1365127

PORCN
Protein-serine O-palmitoleoyltransferase porcupine

1

2

High-throughput

0.445

High

1365131

AT131
Endoplasmic reticulum transmembrane helix translocase

1

5

High-throughput

0.445

High

1365132

EMC7
Endoplasmic reticulum membrane protein complex subunit 7

1

1

High-throughput

0.445

High

1365134

PDXL2
Podocalyxin-like protein 2

1

3

High-throughput

0.445

High

1365139

PRAF1
Prenylated Rab acceptor protein 1

1

1

High-throughput

0.445

High

1365142

TBL2
Transducin beta-like protein 2

1

1

High-throughput

0.445

High

106373

APRIO
Alternative prion protein

1

1

High-throughput

0.437

High

184206

RER1
Protein RER1

1

0

High-throughput

0.426

High

387445

APOE
Apolipoprotein E

1

0

High-throughput

0.426

High

469156

SRPRA
Signal recognition particle receptor subunit alpha

1

0

High-throughput

0.426

High

656207

PPIB
Peptidyl-prolyl cis-trans isomerase B

1

0

High-throughput

0.426

High

773944

SOAT1
Sterol O-acyltransferase 1

1

0

High-throughput

0.426

High

827868

STAT3
Signal transducer and activator of transcription 3

1

0

High-throughput

0.426

High

878067

AGRE5
Adhesion G protein-coupled receptor E5

1

0

High-throughput

0.426

High

1292015

TPRA1
Transmembrane protein adipocyte-associated 1

1

0

High-throughput

0.426

High

1326852

EMC5
ER membrane protein complex subunit 5

1

0

High-throughput

0.426

High

1327911

CISD2
CDGSH iron-sulfur domain-containing protein 2

1

0

High-throughput

0.426

High

1333468

GOLM1
Golgi membrane protein 1

1

0

High-throughput

0.426

High

1365121

EMC6
ER membrane protein complex subunit 6

1

0

High-throughput

0.426

High

1365136

HACD3
Very-long-chain

1

0

High-throughput

0.426

High

1365137

EMC3
ER membrane protein complex subunit 3

1

0

High-throughput

0.426

High

1365140

GGT7
Glutathione hydrolase 7

1

0

High-throughput

0.426

High

136531

GOLI4
Golgi integral membrane protein 4

1

4

High-throughput

0.407

High

343993

HS74L
Heat shock 70 kDa protein 4L

1

11

High-throughput

0.407

High

347848

BAG3
BAG family molecular chaperone regulator 3

1

8

High-throughput

0.407

High

852816

VDAC2
Non-selective voltage-gated ion channel VDAC2

1

4

High-throughput

0.407

High

1162146

MA2A1
Alpha-mannosidase 2

1

1

High-throughput

0.407

High

1273259

HS2ST
Heparan sulfate 2-O-sulfotransferase 1

1

1

High-throughput

0.407

High

1293345

CHSS1
Chondroitin sulfate synthase 1

1

3

High-throughput

0.407

High

1316843

ASPM
Abnormal spindle-like microcephaly-associated protein

1

4

High-throughput

0.407

High

1327701

MACOI
Macoilin

1

2

High-throughput

0.407

High

1329292

CGAT2
Chondroitin sulfate N-acetylgalactosaminyltransferase 2

1

3

High-throughput

0.407

High

1352476

GPX8
Probable glutathione peroxidase 8

1

1

High-throughput

0.407

High

1365135

MTCH1
Mitochondrial carrier homolog 1

1

1

High-throughput

0.407

High

1365138

CHPF2
Chondroitin sulfate glucuronyltransferase

1

3

High-throughput

0.407

High

1365141

VDAC3
Non-selective voltage-gated ion channel VDAC3

1

4

High-throughput

0.407

High

1365145

MTCH2
Mitochondrial carrier homolog 2

1

1

High-throughput

0.407

High

1316616

CDK20
Cyclin-dependent kinase 20

3

0

High-throughput

0.345

High

1324153

PLD6
Mitochondrial cardiolipin hydrolase

3

0

High-throughput

0.345

High

1365117

BROMI
Protein broad-minded

3

0

High-throughput

0.345

High

1365129

FKRP
Ribitol 5-phosphate transferase FKRP

3

0

High-throughput

0.345

High

64575

MP3B2
Microtubule-associated protein 1 light chain 3 beta 2

2

0

High-throughput

0.328

High

1365126

COA1
Cytochrome c oxidase assembly factor 1 homolog

2

0

High-throughput

0.328

High

1216909

TM164
Transmembrane protein 164

1

0

High-throughput

0.279

Low

1365112

CKLF5
CKLF-like MARVEL transmembrane domain-containing protein 5

1

0

High-throughput

0.279

Low

1365113

YIPF6
Protein YIPF6

1

0

High-throughput

0.279

Low

1365130

VAT1L
Synaptic vesicle membrane protein VAT-1 homolog-like

1

0

High-throughput

0.279

Low

278704

NDUS6
NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial

1

0

High-throughput

0.232

Low

322050

ENDD1
Endonuclease domain-containing 1 protein

1

0

High-throughput

0.232

Low

322159

GLCE
D-glucuronyl C5-epimerase

1

0

High-throughput

0.232

Low

331907

GOSR1
Golgi SNAP receptor complex member 1

1

0

High-throughput

0.232

Low

1278050

MAVS
Mitochondrial antiviral-signaling protein

1

0

High-throughput

0.232

Low

1365143

CFA20
Cilia- and flagella-associated protein 20

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025