Protein: TELO2
Telomere length regulation protein TEL2 homolog (Protein clk-2 homolog) (hCLK2)

Gene: TELO2
Organism: Homo sapiens
Interactions: 143
UniProt ID: Q9Y4R8

Gene Ontology (top 5):
GO:0000781 - chromosome, telomeric region
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0016020 - membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

208103

TTI1
TELO2-interacting protein 1 homolog

5

3

Small-scale

0.718

High

1109539

ATR
Serine/threonine-protein kinase ATR

5

16

Small-scale

0.716

High

774726

BASI
Basigin

5

1

High-throughput

0.712

High

1102303

ATM
Serine-protein kinase ATM

4

16

Small-scale

0.706

High

839419

MTOR
Serine/threonine-protein kinase mTOR

3

16

Small-scale

0.684

High

1008415

PRKDC
DNA-dependent protein kinase catalytic subunit

3

16

Small-scale

0.667

High

1247061

RICTR
Rapamycin-insensitive companion of mTOR

3

1

Small-scale

0.656

High

1490522

RUVB1
RuvB-like 1

2

5

Small-scale

0.628

High

1400496

SMG1
Serine/threonine-protein kinase SMG1

2

16

Small-scale

0.611

High

1490461

RUVB2
RuvB-like 2

2

5

Small-scale

0.611

High

1491354

TRRAP
Transformation/transcription domain-associated protein

2

16

Small-scale

0.611

High

1451339

PIHD1
PIH1 domain-containing protein 1

1

2

Small-scale

0.604

High

1239432

TTI2
TELO2-interacting protein 2

2

0

Small-scale

0.602

High

1435203

RPAP3
RNA polymerase II-associated protein 3

2

3

Small-scale

0.601

High

1322686

RPTOR
Regulatory-associated protein of mTOR

2

0

Small-scale

0.585

High

1314886

FANCM
Fanconi anemia group M protein

2

0

Small-scale

0.559

High

1370797

PTPR2
Receptor-type tyrosine-protein phosphatase N2

2

1

High-throughput

0.558

High

1491455

NPTN
Neuroplastin

2

1

High-throughput

0.549

High

622489

ELK1
ETS domain-containing protein Elk-1

2

0

High-throughput

0.547

High

182853

GP182
G-protein coupled receptor 182

1

2

High-throughput

0.536

High

538723

GTR1
Solute carrier family 2, facilitated glucose transporter member 1

1

1

High-throughput

0.536

High

638561

FPR1
fMet-Leu-Phe receptor

1

2

High-throughput

0.536

High

1392531

GWL
Serine/threonine-protein kinase greatwall

1

2

High-throughput

0.536

High

1460969

FBX9
F-box only protein 9

1

0

Small-scale

0.530

High

348812

AIFM1
Apoptosis-inducing factor 1, mitochondrial

1

0

High-throughput

0.513

High

587847

DESP
Desmoplakin

1

0

High-throughput

0.513

High

668765

APC
Adenomatous polyposis coli protein

1

0

High-throughput

0.513

High

679302

DNJB1
DnaJ homolog subfamily B member 1

1

0

Small-scale

0.513

High

855960

CRKL
Crk-like protein

1

0

High-throughput

0.513

High

905715

IRAK1
Interleukin-1 receptor-associated kinase 1

1

0

High-throughput

0.513

High

1006977

CLD10
Claudin-10

1

0

High-throughput

0.513

High

1041809

PPARD
Peroxisome proliferator-activated receptor delta

1

0

High-throughput

0.513

High

1053090

VMAT2
Synaptic vesicular amine transporter

1

0

High-throughput

0.513

High

1101204

CLN3
Battenin

1

0

High-throughput

0.513

High

1129203

IRF3
Interferon regulatory factor 3

1

0

High-throughput

0.513

High

1161280

MK06
Mitogen-activated protein kinase 6

1

0

High-throughput

0.513

High

1325960

MFD4A
Major facilitator superfamily domain-containing protein 4A

1

0

High-throughput

0.513

High

1339776

TNIP2
TNFAIP3-interacting protein 2

1

0

High-throughput

0.513

High

1349154

F174A
Membrane protein FAM174A

1

0

High-throughput

0.513

High

1363261

AQP3
Aquaporin-3

1

0

High-throughput

0.513

High

1369517

TANK
TRAF family member-associated NF-kappa-B activator

1

0

High-throughput

0.513

High

1383904

EFMT3
EEF1A lysine methyltransferase 3

1

0

High-throughput

0.513

High

1420273

UBXN6
UBX domain-containing protein 6

1

0

High-throughput

0.513

High

1434779

CIA2A
Cytosolic iron-sulfur assembly component 2A

1

0

High-throughput

0.513

High

1491452

CTDP1
RNA polymerase II subunit A C-terminal domain phosphatase

1

0

High-throughput

0.513

High

831709

CCNF
Cyclin-F

1

0

High-throughput

0.493

High

1136630

PSMD6
26S proteasome non-ATPase regulatory subunit 6

1

0

High-throughput

0.493

High

1491453

MAGD1
Melanoma-associated antigen D1

1

0

High-throughput

0.493

High

927187

ATX3
Ataxin-3

1

0

High-throughput

0.493

High

133323

P2Y10
Putative P2Y purinoceptor 10

1

4

High-throughput

0.489

High

618431

TSN8
Tetraspanin-8

1

1

High-throughput

0.489

High

879822

NPY2R
Neuropeptide Y receptor type 2

1

2

High-throughput

0.489

High

936142

PAR2
Proteinase-activated receptor 2

1

4

High-throughput

0.489

High

1291925

P2RY8
S-geranylgeranyl-glutathione receptor P2RY8

1

4

High-throughput

0.489

High

1350239

PKR1
Prokineticin receptor 1

1

2

High-throughput

0.489

High

1431028

UN93B
Protein unc-93 homolog B1

1

1

High-throughput

0.489

High

1454434

C5AR2
C5a anaphylatoxin chemotactic receptor 2

1

2

High-throughput

0.489

High

1490919

GPR55
G-protein coupled receptor 55

1

5

High-throughput

0.489

High

1491454

GPR45
Probable G-protein coupled receptor 45

1

2

High-throughput

0.489

High

139757

CAC1A
Voltage-dependent P/Q-type calcium channel subunit alpha-1A

1

0

High-throughput

0.486

High

618134

K1C15
Keratin, type I cytoskeletal 15

1

0

High-throughput

0.486

High

731737

STIP1
Stress-induced-phosphoprotein 1

1

2

High-throughput

0.479

High

1052859

DUSP2
Dual specificity protein phosphatase 2

1

1

High-throughput

0.479

High

1146498

KS6A2
Ribosomal protein S6 kinase alpha-2

1

1

High-throughput

0.479

High

1148413

KS6A1
Ribosomal protein S6 kinase alpha-1

1

1

High-throughput

0.479

High

1163910

DUS7
Dual specificity protein phosphatase 7

1

1

High-throughput

0.479

High

1356906

PTPM1
Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1

1

2

High-throughput

0.479

High

1405924

DNJC7
DnaJ homolog subfamily C member 7

1

2

High-throughput

0.479

High

1438266

RHOF
Rho-related GTP-binding protein RhoF

1

1

High-throughput

0.479

High

173607

XPO1
Exportin-1

1

0

High-throughput

0.458

High

174648

TRI66
Tripartite motif-containing protein 66

1

0

High-throughput

0.458

High

176581

GRRE1
Granule associated Rac and RHOG effector protein 1

1

0

High-throughput

0.458

High

243396

PRKN
E3 ubiquitin-protein ligase parkin

1

0

High-throughput

0.458

High

279552

TULP3
Tubby-related protein 3

1

0

High-throughput

0.458

High

294583

CD123
Translation initiation factor eIF2 assembly protein

1

0

High-throughput

0.458

High

342386

BRD1
Bromodomain-containing protein 1

1

0

High-throughput

0.458

High

364085

EGFR
Epidermal growth factor receptor

1

0

High-throughput

0.458

High

520483

ANDR
Androgen receptor

1

0

High-throughput

0.458

High

590129

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.458

High

696968

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

761943

HSP74
Heat shock 70 kDa protein 4

1

0

Small-scale

0.458

High

935347

TERA
Transitional endoplasmic reticulum ATPase

1

0

High-throughput

0.458

High

941994

PEX3
Peroxisomal biogenesis factor 3

1

0

High-throughput

0.458

High

955788

CDC42
Cell division control protein 42 homolog

1

0

High-throughput

0.458

High

1106766

SMAD4
Mothers against decapentaplegic homolog 4

1

0

High-throughput

0.458

High

1114749

CUL3
Cullin-3

1

0

High-throughput

0.458

High

1135872

HAPR1
HUWE1-associated protein modifying stress responses 1

1

0

High-throughput

0.458

High

1152504

T22D1
TSC22 domain family protein 1

1

0

High-throughput

0.458

High

1161455

HIF1A
Hypoxia-inducible factor 1-alpha

1

0

High-throughput

0.458

High

1178482

CL16A
Protein CLEC16A

1

0

High-throughput

0.458

High

1253022

BAKOR
Beclin 1-associated autophagy-related key regulator

1

0

High-throughput

0.458

High

1256255

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.458

High

1277032

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.458

High

1280636

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

0

High-throughput

0.458

High

1309924

TEX2
Testis-expressed protein 2

1

0

High-throughput

0.458

High

1360361

ATRIP
ATR-interacting protein

1

0

Small-scale

0.458

High

1364319

TOPB1
DNA topoisomerase 2-binding protein 1

1

0

Small-scale

0.458

High

1397598

CI072
Guanine nucleotide exchange factor C9orf72

1

0

High-throughput

0.458

High

1398631

DAA10
Dynein axonemal assembly factor 10

1

0

High-throughput

0.458

High

1401266

PANX1
Pannexin-1

1

0

High-throughput

0.458

High

1413602

FAP24
Fanconi anemia core complex-associated protein 24

1

0

Small-scale

0.458

High

1418552

ACE2
Angiotensin-converting enzyme 2

1

0

High-throughput

0.458

High

1429416

SPRTN
DNA-dependent metalloprotease SPRTN

1

0

High-throughput

0.458

High

1433817

SENP3
Sentrin-specific protease 3

1

0

Small-scale

0.458

High

1434332

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.458

High

1435498

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.458

High

1437998

PIDD1
p53-induced death domain-containing protein 1

1

0

Small-scale

0.458

High

1448861

TMPS4
Transmembrane protease serine 4

1

0

High-throughput

0.458

High

1453066

TLS1
Splicing factor C9orf78

1

0

High-throughput

0.458

High

1459899

UBQL2
Ubiquilin-2

1

0

High-throughput

0.458

High

166461

ZNT4
Probable proton-coupled zinc antiporter SLC30A4

1

1

High-throughput

0.445

High

538823

GTR2
Solute carrier family 2, facilitated glucose transporter member 2

1

1

High-throughput

0.445

High

1292385

UN93A
Protein unc-93 homolog A

1

1

High-throughput

0.445

High

1338023

ZNT7
Zinc transporter 7

1

1

High-throughput

0.445

High

1449967

S39A9
Zinc transporter ZIP9

1

1

High-throughput

0.445

High

1371343

KAT5
Histone acetyltransferase KAT5

1

0

High-throughput

0.438

High

1452403

B3GN2
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2

1

1

High-throughput

0.437

High

1170

SIM26
Small integral membrane protein 26

1

0

High-throughput

0.426

High

380206

HLAB
HLA class I histocompatibility antigen, B alpha chain

1

0

High-throughput

0.426

High

564611

CFTR
Cystic fibrosis transmembrane conductance regulator

1

0

High-throughput

0.426

High

1209839

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

0

High-throughput

0.426

High

1227776

A16L1
Autophagy-related protein 16-1

1

0

High-throughput

0.426

High

1240991

S27A4
Long-chain fatty acid transport protein 4

1

0

High-throughput

0.426

High

1332342

NLS1
Sodium-dependent lysophosphatidylcholine symporter 1

1

0

High-throughput

0.426

High

1451543

CLN6
Ceroid-lipofuscinosis neuronal protein 6

1

0

Small-scale

0.426

High

1209929

PPM1L
Protein phosphatase 1L

1

1

High-throughput

0.407

High

1335797

MOT11
Monocarboxylate transporter 11

1

1

High-throughput

0.407

High

1412083

S39A3
Zinc transporter ZIP3

1

1

High-throughput

0.407

High

630202

ACM3
Muscarinic acetylcholine receptor M3

1

0

High-throughput

0.279

Low

771272

APJ
Apelin receptor

1

0

High-throughput

0.279

Low

1325863

D2HDH
D-2-hydroxyglutarate dehydrogenase, mitochondrial

1

0

High-throughput

0.279

Low

1350927

HUMMR
Protein MGARP

1

0

High-throughput

0.279

Low

1399651

OPALI
Opalin

1

0

High-throughput

0.279

Low

124543

HAX1
HCLS1-associated protein X-1

1

0

High-throughput

0.249

Low

412878

NTRK1
High affinity nerve growth factor receptor

1

0

High-throughput

0.249

Low

769609

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

895225

5HT6R
5-hydroxytryptamine receptor 6

1

0

Small-scale

0.249

Low

1249364

LMBRL
Protein LMBR1L

1

0

High-throughput

0.249

Low

1308244

PLD3
5'-3' exonuclease PLD3

1

0

High-throughput

0.249

Low

1366853

PTPRU
Receptor-type tyrosine-protein phosphatase U

1

0

High-throughput

0.249

Low

1383726

VP33A
Vacuolar protein sorting-associated protein 33A

1

0

High-throughput

0.249

Low

1453562

PD1L1
Programmed cell death 1 ligand 1

1

0

High-throughput

0.249

Low

1381045

S35B4
Nucleotide sugar transporter SLC35B4

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025