Protein: GDNF
Glial cell line-derived neurotrophic factor (hGDNF) (Astrocyte-derived trophic factor) (ATF)

Gene: GDNF
Organism: Homo sapiens
Interactions: 27
UniProt ID: P39905

Gene Ontology (top 5):
GO:0001656 - metanephros development
GO:0001658 - branching involved in ureteric bud morphogenesis
GO:0001755 - neural crest cell migration
GO:0001759 - organ induction
GO:0001941 - postsynaptic membrane organization

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

814913

GFRA1
GDNF family receptor alpha-1

3

7

Small-scale

0.845

High

136177

GFRA2
GDNF family receptor alpha-2

2

7

Small-scale

0.778

High

814922

SORL
Sortilin-related receptor

1

0

Small-scale

0.646

High

814919

ARMC8
Armadillo repeat-containing protein 8

3

0

High-throughput

0.638

High

814916

ATRAP
Type-1 angiotensin II receptor-associated protein

2

0

High-throughput

0.626

High

463915

RET
Proto-oncogene tyrosine-protein kinase receptor Ret

1

1

High-throughput

0.618

High

814912

GDNF
Glial cell line-derived neurotrophic factor

1

1

High-throughput

0.618

High

814918

MAEA
E3 ubiquitin-protein transferase MAEA

3

3

High-throughput

0.609

High

590256

MUC1
Mucin-1

2

0

High-throughput

0.580

High

614662

PTPRA
Receptor-type tyrosine-protein phosphatase alpha

2

1

High-throughput

0.571

High

814917

RBP10
Ran-binding protein 10

2

1

High-throughput

0.558

High

658956

PTPRE
Receptor-type tyrosine-protein phosphatase epsilon

1

1

High-throughput

0.479

High

814927

MKLN1
Muskelin

1

1

High-throughput

0.479

High

330725

KI20A
Kinesin-like protein KIF20A

1

0

High-throughput

0.458

High

723709

NEUT
Neurotensin/neuromedin N [Cleaved into: Large neuromedin N

1

0

Small-scale

0.458

High

814914

S10AA
Protein S100-A10

1

0

High-throughput

0.458

High

814915

YPEL5
Protein yippee-like 5

1

0

High-throughput

0.458

High

814923

CSN5
COP9 signalosome complex subunit 5

1

0

High-throughput

0.458

High

814925

CHM4B
Charged multivesicular body protein 4b

1

0

High-throughput

0.458

High

814924

RANB9
Ran-binding protein 9

1

1

High-throughput

0.437

High

814926

RMD5A
E3 ubiquitin-protein transferase RMND5A

1

2

High-throughput

0.437

High

814920

GID4
Glucose-induced degradation protein 4 homolog

3

0

High-throughput

0.347

High

469465

SYPH
Synaptophysin

2

0

High-throughput

0.316

High

814921

SCAM5
Secretory carrier-associated membrane protein 5

2

0

High-throughput

0.316

High

278628

NDUS6
NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial

1

0

High-throughput

0.249

Low

606084

DESM
Desmin

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025