Protein: MRTFA
Myocardin-related transcription factor A (MRTF-A) (MKL/myocardin-like protein 1) (Megakaryoblastic leukemia 1 protein) (Megakaryocytic acute leukemia protein)

Gene: MRTFA
Organism: Homo sapiens
Interactions: 55
UniProt ID: Q969V6

Gene Ontology (top 5):
GO:0003713 - transcription coactivator activity
GO:0003779 - actin binding
GO:0003785 - actin monomer binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

953019

ACTB
Actin, cytoplasmic 1

3

20

Small-scale

0.847

High

549346

SRF
Serum response factor

5

9

Small-scale

0.709

High

993285

ACTG
Actin, cytoplasmic 2

1

20

High-throughput

0.691

High

995750

ACTC
Actin, alpha cardiac muscle 1

1

19

High-throughput

0.665

High

1381428

MRTFB
Myocardin-related transcription factor B

1

18

Small-scale

0.665

High

1316804

MYCD
Myocardin

1

17

Small-scale

0.647

High

1045611

TF65
Transcription factor p65

3

13

Small-scale

0.640

High

1196902

BCL7A
B-cell CLL/lymphoma 7 protein family member A

2

2

High-throughput

0.628

High

703677

MK01
Mitogen-activated protein kinase 1

2

7

High-throughput

0.571

High

903452

SMCA4
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4

1

11

Small-scale

0.561

High

347226

BAG2
BAG family molecular chaperone regulator 2

1

4

High-throughput

0.536

High

931042

HSP72
Heat shock-related 70 kDa protein 2

1

6

High-throughput

0.536

High

1123072

FHL2
Four and a half LIM domains protein 2

1

17

High-throughput

0.536

High

1381424

MLP3B
Microtubule-associated protein 1 light chain 3 beta

1

17

High-throughput

0.501

High

1381425

MLP3A
Microtubule-associated protein 1 light chain 3 alpha

1

17

High-throughput

0.501

High

1381430

KDM3A
Lysine-specific demethylase 3A

1

8

Small-scale

0.501

High

1381432

NCOA3
Nuclear receptor coactivator 3

1

19

Small-scale

0.501

High

1381422

FUND2
FUN14 domain-containing protein 2

1

0

High-throughput

0.493

High

706249

S10A2
Protein S100-A2

1

2

High-throughput

0.489

High

1131986

MVP
Major vault protein

1

1

High-throughput

0.481

High

1381423

TRI54
Tripartite motif-containing protein 54

1

16

High-throughput

0.481

High

138740

IMA4
Importin subunit alpha-4

1

2

Small-scale

0.479

High

173180

XPO1
Exportin-1

1

12

High-throughput

0.479

High

246837

KDM1A
Lysine-specific histone demethylase 1A

1

11

High-throughput

0.479

High

459712

PROF1
Profilin-1

1

6

High-throughput

0.479

High

558997

LYL1
Protein lyl-1

1

10

High-throughput

0.479

High

593180

CREB1
Cyclic AMP-responsive element-binding protein 1

1

1

High-throughput

0.479

High

613130

EGR1
Early growth response protein 1

1

6

High-throughput

0.479

High

613425

VINC
Vinculin

1

6

High-throughput

0.479

High

685043

DNMT1
DNA

1

3

Small-scale

0.479

High

891718

GSK3B
Glycogen synthase kinase-3 beta

1

6

Small-scale

0.479

High

896601

VASP
Vasodilator-stimulated phosphoprotein

1

8

High-throughput

0.479

High

986619

PPIA
Peptidyl-prolyl cis-trans isomerase A

1

7

High-throughput

0.479

High

1014577

SMAD3
Mothers against decapentaplegic homolog 3

1

17

Small-scale

0.479

High

1065346

SSRP1
FACT complex subunit SSRP1

1

19

Small-scale

0.479

High

1067584

EP300
Histone acetyltransferase p300

1

18

Small-scale

0.479

High

1109967

HDAC1
Histone deacetylase 1

1

13

High-throughput

0.479

High

1115346

CUL4B
Cullin-4B

1

15

High-throughput

0.479

High

1131096

UBP10
Ubiquitin carboxyl-terminal hydrolase 10

1

5

Small-scale

0.479

High

1156174

ZYX
Zyxin

1

13

High-throughput

0.479

High

1291336

LCA5
Lebercilin

1

12

High-throughput

0.479

High

1381417

PF21A
PHD finger protein 21A

1

18

High-throughput

0.479

High

1381418

RPGR1
X-linked retinitis pigmentosa GTPase regulator-interacting protein 1

1

16

High-throughput

0.479

High

1381419

SNX27
Sorting nexin-27

1

15

High-throughput

0.479

High

1381421

CEP63
Centrosomal protein of 63 kDa

1

16

High-throughput

0.479

High

1381427

RCOR1
REST corepressor 1

1

14

High-throughput

0.479

High

1381429

TRRAP
Transformation/transcription domain-associated protein

1

11

High-throughput

0.479

High

1381431

SP16H
FACT complex subunit SPT16

1

1

Small-scale

0.479

High

278925

PEX14
Peroxisomal membrane protein PEX14

1

0

High-throughput

0.458

High

1177984

MOONR
Protein moonraker

1

0

High-throughput

0.458

High

1179121

TECT1
Tectonic-1

1

0

High-throughput

0.458

High

1381420

CEP19
Centrosomal protein of 19 kDa

1

0

High-throughput

0.458

High

372772

MYC
Myc proto-oncogene protein

1

18

High-throughput

0.445

High

848815

MAGAA
Melanoma-associated antigen 10

1

6

High-throughput

0.445

High

1381426

KBTB4
Kelch repeat and BTB domain-containing protein 4

1

6

High-throughput

0.437

High


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Last updated: 11Aug2025