Protein: MRTFB
Myocardin-related transcription factor B (MRTF-B) (MKL/myocardin-like protein 2) (Megakaryoblastic leukemia 2)

Gene: MRTFB
Organism: Homo sapiens
Interactions: 57
UniProt ID: Q9ULH7

Gene Ontology (top 5):
GO:0003713 - transcription coactivator activity
GO:0005634 - nucleus
GO:0007517 - muscle organ development
GO:0045296 - cadherin binding
GO:0045844 - positive regulation of striated muscle tissue development

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

953176

ACTB
Actin, cytoplasmic 1

1

16

High-throughput

0.691

High

993379

ACTG
Actin, cytoplasmic 2

1

16

High-throughput

0.691

High

1116620

FHL3
Four and a half LIM domains protein 3

3

13

High-throughput

0.667

High

1381428

MRTFA
Myocardin-related transcription factor A

1

18

Small-scale

0.665

High

1461577

MRTFB
Myocardin-related transcription factor B

1

10

Small-scale

0.665

High

558487

XRCC6
X-ray repair cross-complementing protein 6

1

3

High-throughput

0.618

High

995889

ACTC
Actin, alpha cardiac muscle 1

1

13

High-throughput

0.618

High

549358

SRF
Serum response factor

2

5

Small-scale

0.612

High

1196922

BCL7A
B-cell CLL/lymphoma 7 protein family member A

2

2

High-throughput

0.574

High

397198

ESR1
Estrogen receptor

2

20

High-throughput

0.571

High

703743

MK01
Mitogen-activated protein kinase 1

2

4

High-throughput

0.571

High

1123176

FHL2
Four and a half LIM domains protein 2

1

13

High-throughput

0.536

High

1163281

H2B2E
Histone H2B type 2-E

1

20

High-throughput

0.515

High

177728

SMAD7
Mothers against decapentaplegic homolog 7

1

7

High-throughput

0.508

High

1154024

SMAD1
Mothers against decapentaplegic homolog 1

1

7

High-throughput

0.508

High

1461579

KDM3A
Lysine-specific demethylase 3A

1

7

Small-scale

0.501

High

1461580

NCOA3
Nuclear receptor coactivator 3

1

5

Small-scale

0.501

High

347407

BAG2
BAG family molecular chaperone regulator 2

1

3

High-throughput

0.489

High

483256

CLCA
Clathrin light chain A

1

2

High-throughput

0.489

High

129543

MEN1
Menin

1

6

High-throughput

0.479

High

173541

XPO1
Exportin-1

1

6

High-throughput

0.479

High

243271

PRKN
E3 ubiquitin-protein ligase parkin

1

7

High-throughput

0.479

High

247022

KDM1A
Lysine-specific histone demethylase 1A

1

9

High-throughput

0.479

High

538103

HSP7C
Heat shock cognate 71 kDa protein

1

4

High-throughput

0.479

High

552727

IMDH2
Inosine-5'-monophosphate dehydrogenase 2

1

2

High-throughput

0.479

High

556414

CADH1
Cadherin-1

1

4

High-throughput

0.479

High

831635

CCNF
Cyclin-F

1

2

High-throughput

0.479

High

862542

YAP1
Transcriptional coactivator YAP1

1

15

High-throughput

0.479

High

935278

TERA
Transitional endoplasmic reticulum ATPase

1

2

High-throughput

0.479

High

1110181

HDAC1
Histone deacetylase 1

1

15

High-throughput

0.479

High

1142018

EEA1
Early endosome antigen 1

1

9

High-throughput

0.479

High

1280591

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

9

High-throughput

0.479

High

1289712

NAA40
N-alpha-acetyltransferase 40

1

4

High-throughput

0.479

High

1364301

TOPB1
DNA topoisomerase 2-binding protein 1

1

8

High-throughput

0.479

High

1367567

ESR2
Estrogen receptor beta

1

20

High-throughput

0.479

High

1405704

NECD
Necdin

1

4

High-throughput

0.479

High

1459282

ZRAN1
Ubiquitin thioesterase ZRANB1

1

7

High-throughput

0.479

High

1461127

RCOR1
REST corepressor 1

1

10

High-throughput

0.479

High

336513

SVIL
Supervillin

1

0

Small-scale

0.460

High

330368

VENTX
Homeobox protein VENTX

1

9

High-throughput

0.445

High

765995

BMI1
Polycomb complex protein BMI-1

1

8

High-throughput

0.445

High

1203287

ODFP2
Outer dense fiber protein 2

1

6

High-throughput

0.445

High

1241980

FBX42
F-box only protein 42

1

6

High-throughput

0.437

High

1256062

TRI67
Tripartite motif-containing protein 67

1

16

High-throughput

0.437

High

1339031

NUP43
Nucleoporin Nup43

1

17

High-throughput

0.437

High

1363891

GBF1
Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1

1

4

High-throughput

0.437

High

1384474

PF21A
PHD finger protein 21A

1

16

High-throughput

0.437

High

1434419

RNF41
E3 ubiquitin-protein ligase NRDP1

1

8

Small-scale

0.437

High

1450971

KBTB4
Kelch repeat and BTB domain-containing protein 4

1

3

High-throughput

0.437

High

1460579

HOOK1
Protein Hook homolog 1

1

6

High-throughput

0.437

High

142634

IMA3
Importin subunit alpha-3

1

1

High-throughput

0.408

High

1461578

ST38L
Serine/threonine-protein kinase 38-like

1

6

High-throughput

0.407

High

317946

LTN1
E3 ubiquitin-protein ligase listerin

1

0

High-throughput

0.249

Low

1333368

NHLC2
NHL repeat-containing protein 2

1

0

High-throughput

0.249

Low

1404278

SEC62
Translocation protein SEC62

1

0

High-throughput

0.249

Low

1447004

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

0

Small-scale

0.249

Low


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Last updated: 11Aug2025