Protein: KDM3A
Lysine-specific demethylase 3A (EC 1.14.11.65) (JmjC domain-containing histone demethylation protein 2A) (Jumonji domain-containing protein 1A) ([histone H3]-dimethyl-L-lysine(9) demethylase 3A)

Gene: KDM3A
Organism: Homo sapiens
Interactions: 54
UniProt ID: Q9Y4C1

Gene Ontology (top 5):
GO:0000118 - histone deacetylase complex
GO:0000785 - chromatin
GO:0001673 - male germ cell nucleus
GO:0003712 - transcription coregulator activity
GO:0005506 - iron ion binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1143880

TCAL1
Transcription elongation factor A protein-like 1

5

0

High-throughput

0.686

High

287744

KS6A5
Ribosomal protein S6 kinase alpha-5

1

1

Small-scale

0.586

High

1161453

HIF1A
Hypoxia-inducible factor 1-alpha

2

1

Small-scale

0.584

High

132535

ETV2
ETS translocation variant 2

1

1

Small-scale

0.561

High

1368782

SYMPK
Symplekin

2

0

High-throughput

0.559

High

1014238

CBX1
Chromobox protein homolog 1

1

15

High-throughput

0.536

High

1132252

CBX2
Chromobox protein homolog 2

1

15

High-throughput

0.536

High

1216054

TTBK1
Tau-tubulin kinase 1

1

4

High-throughput

0.536

High

1123558

BTG3
Protein BTG3

1

0

High-throughput

0.518

High

813264

OST48
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit

1

0

High-throughput

0.513

High

959099

RPAB2
DNA-directed RNA polymerases I, II, and III subunit RPABC2

1

0

High-throughput

0.513

High

1242401

GOLM2
Protein GOLM2

1

0

High-throughput

0.513

High

838205

STAT1
Signal transducer and activator of transcription 1-alpha/beta

1

0

Small-scale

0.512

High

1258992

H32
Histone H3.2

1

12

Small-scale

0.501

High

1316808

MYCD
Myocardin

1

8

Small-scale

0.501

High

1381430

MRTFA
Myocardin-related transcription factor A

1

8

Small-scale

0.501

High

1461579

MRTFB
Myocardin-related transcription factor B

1

7

Small-scale

0.501

High

1404077

MYCBP
c-Myc-binding protein

1

0

High-throughput

0.493

High

1308806

NAV3
Neuron navigator 3

1

1

High-throughput

0.489

High

214473

RIPK2
Receptor-interacting serine/threonine-protein kinase 2

1

0

High-throughput

0.486

High

129833

CBX4
E3 SUMO-protein ligase CBX4

1

15

High-throughput

0.479

High

143351

NFIB
Nuclear factor 1 B-type

1

8

High-throughput

0.479

High

373597

MYC
Myc proto-oncogene protein

1

9

High-throughput

0.479

High

378527

IL1A
Interleukin-1 alpha

1

1

Small-scale

0.479

High

474401

NFIC
Nuclear factor 1 C-type

1

11

High-throughput

0.479

High

520480

ANDR
Androgen receptor

1

17

Small-scale

0.479

High

613237

EGR1
Early growth response protein 1

1

1

High-throughput

0.479

High

714547

PML
Protein PML

1

9

High-throughput

0.479

High

786955

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

1

4

High-throughput

0.479

High

862580

YAP1
Transcriptional coactivator YAP1

1

9

High-throughput

0.479

High

887379

CEBPA
CCAAT/enhancer-binding protein alpha

1

6

High-throughput

0.479

High

995918

ACTC
Actin, alpha cardiac muscle 1

1

3

High-throughput

0.479

High

999001

H31
Histone H3.1

1

12

High-throughput

0.479

High

1017330

H33
Histone H3.3

1

12

High-throughput

0.479

High

1048143

TLE3
Transducin-like enhancer protein 3

1

5

High-throughput

0.479

High

1060816

ACK1
Activated CDC42 kinase 1

1

5

Small-scale

0.479

High

1088124

NFIA
Nuclear factor 1 A-type

1

12

High-throughput

0.479

High

1097650

CBX3
Chromobox protein homolog 3

1

15

High-throughput

0.479

High

1114739

CUL3
Cullin-3

1

5

High-throughput

0.479

High

1133755

NFIX
Nuclear factor 1 X-type

1

12

High-throughput

0.479

High

1145568

RBBP5
Retinoblastoma-binding protein 5

1

3

High-throughput

0.479

High

1277023

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

7

High-throughput

0.479

High

1280631

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

3

Small-scale

0.479

High

1339065

NUP43
Nucleoporin Nup43

1

8

High-throughput

0.479

High

1387660

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

1

3

High-throughput

0.479

High

1452493

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

3

High-throughput

0.479

High

1460329

XPO7
Exportin-7

1

4

High-throughput

0.479

High

1461316

NUP50
Nuclear pore complex protein Nup50

1

1

High-throughput

0.479

High

599640

STMN1
Stathmin

1

0

High-throughput

0.458

High

971348

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.458

High

1337736

PDZD8
PDZ domain-containing protein 8

1

0

High-throughput

0.458

High

1256376

RASF6
Ras association domain-containing protein 6

3

0

High-throughput

0.347

High

505212

OST4
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 4

1

0

High-throughput

0.279

Low

1163343

LAMA3
Laminin subunit alpha-3

1

0

High-throughput

0.269

Low


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Last updated: 11Aug2025