Protein: STEEP
STING ER exit protein (STEEP)

Gene: STEEP, STEEP1
Organism: Homo sapiens
Interactions: 77
UniProt ID: Q9H5V9

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1357088

CATIN
Splicing factor Cactin

3

2

High-throughput

0.667

High

386233

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

3

1

High-throughput

0.640

High

998809

H31
Histone H3.1

2

2

High-throughput

0.584

High

168325

HAT1
Histone acetyltransferase type B catalytic subunit

2

0

High-throughput

0.580

High

1434733

KIF9
Kinesin-like protein KIF9

2

0

High-throughput

0.580

High

1434734

RPR1B
Regulation of nuclear pre-mRNA domain-containing protein 1B

2

0

High-throughput

0.580

High

1434738

ZRAN1
Ubiquitin thioesterase ZRANB1

2

0

High-throughput

0.559

High

1391043

OTUB1
Ubiquitin thioesterase OTUB1

2

0

High-throughput

0.547

High

1434737

IKBL1
NF-kappa-B inhibitor-like protein 1

1

0

High-throughput

0.523

High

1128114

DHX8
ATP-dependent RNA helicase DHX8

1

0

High-throughput

0.513

High

1434741

TNPO3
Transportin-3

1

0

High-throughput

0.513

High

1111271

SNW1
SNW domain-containing protein 1

1

0

High-throughput

0.486

High

1416117

RBM4
RNA-binding protein 4

1

0

High-throughput

0.486

High

1361159

PIBF1
Progesterone-induced-blocking factor 1

1

1

High-throughput

0.481

High

423168

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.480

High

247430

PHLP1
PH domain leucine-rich repeat-containing protein phosphatase 1

1

1

High-throughput

0.479

High

302640

RNF8
E3 ubiquitin-protein ligase RNF8

1

1

Small-scale

0.479

High

355599

NSD2
Histone-lysine N-methyltransferase NSD2

1

2

Small-scale

0.479

High

373148

MYC
Myc proto-oncogene protein

1

1

High-throughput

0.479

High

406640

MYCN
N-myc proto-oncogene protein

1

1

High-throughput

0.479

High

634638

LMNB1
Lamin-B1

1

1

High-throughput

0.479

High

862461

YAP1
Transcriptional coactivator YAP1

1

1

High-throughput

0.479

High

883690

CENPA
Histone H3-like centromeric protein A

1

2

High-throughput

0.479

High

1017211

H33
Histone H3.3

1

2

High-throughput

0.479

High

1155771

EZH2
Histone-lysine N-methyltransferase EZH2

1

1

High-throughput

0.479

High

1428971

WWTR1
WW domain-containing transcription regulator protein 1

1

1

High-throughput

0.479

High

1194586

Q4G0R1
PIBF1 protein

1

1

High-throughput

0.470

High

1326481

PDCL2
Phosducin-like protein 2

1

0

High-throughput

0.460

High

141109

NOP56
Nucleolar protein 56

1

0

High-throughput

0.458

High

191093

RPA34
DNA-directed RNA polymerase I subunit RPA34

1

0

High-throughput

0.458

High

260455

BRD4
Bromodomain-containing protein 4

1

0

High-throughput

0.458

High

316014

RECQ4
ATP-dependent DNA helicase Q4

1

0

High-throughput

0.458

High

537912

HSP7C
Heat shock cognate 71 kDa protein

1

0

High-throughput

0.458

High

558404

XRCC6
X-ray repair cross-complementing protein 6

1

0

High-throughput

0.458

High

564371

CFTR
Cystic fibrosis transmembrane conductance regulator

1

0

High-throughput

0.458

High

589685

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.458

High

696505

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

697255

APEX1
DNA repair nuclease/redox regulator APEX1

1

0

High-throughput

0.458

High

714430

PML
Protein PML

1

0

High-throughput

0.458

High

769176

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.458

High

800104

COIL
Coilin

1

0

High-throughput

0.458

High

971079

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.458

High

979239

RS6
Small ribosomal subunit protein eS6

1

0

High-throughput

0.458

High

980324

H4
Histone H4

1

0

High-throughput

0.458

High

981098

H2B1C
Histone H2B type 1-C/E/F/G/I

1

0

High-throughput

0.458

High

982828

RS24
Small ribosomal subunit protein eS24

1

0

High-throughput

0.458

High

984985

RL31
Large ribosomal subunit protein eL31

1

0

High-throughput

0.458

High

986726

PPIA
Peptidyl-prolyl cis-trans isomerase A

1

0

High-throughput

0.458

High

995821

ACTC
Actin, alpha cardiac muscle 1

1

0

High-throughput

0.458

High

1008886

RED1
Double-stranded RNA-specific editase 1

1

0

High-throughput

0.458

High

1097563

CBX3
Chromobox protein homolog 3

1

0

High-throughput

0.458

High

1108153

SQSTM
Sequestosome-1

1

0

High-throughput

0.458

High

1138060

TNIP1
TNFAIP3-interacting protein 1

1

0

High-throughput

0.458

High

1152636

ELAV1
ELAV-like protein 1

1

0

High-throughput

0.458

High

1289630

NAA40
N-alpha-acetyltransferase 40

1

0

High-throughput

0.458

High

1313432

SMC5
Structural maintenance of chromosomes protein 5

1

0

High-throughput

0.458

High

1314421

SLX4
Structure-specific endonuclease subunit SLX4

1

0

High-throughput

0.458

High

1364257

TOPB1
DNA topoisomerase 2-binding protein 1

1

0

High-throughput

0.458

High

1371929

STMN2
Stathmin-2

1

0

High-throughput

0.458

High

1404400

CDC5L
Cell division cycle 5-like protein

1

0

High-throughput

0.458

High

1418583

MK67I
MKI67 FHA domain-interacting nucleolar phosphoprotein

1

0

High-throughput

0.458

High

1420929

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

0

High-throughput

0.458

High

1429980

SHRPN
Sharpin

1

0

Small-scale

0.458

High

1432711

TXNIP
Thioredoxin-interacting protein

1

0

Small-scale

0.458

High

1433887

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.458

High

1434736

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

0

High-throughput

0.458

High

1434739

ASF1A
Histone chaperone ASF1A

1

0

High-throughput

0.458

High

1434735

KBTB4
Kelch repeat and BTB domain-containing protein 4

1

1

High-throughput

0.437

High

430361

JUN
Transcription factor Jun

1

0

High-throughput

0.426

High

1209659

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

0

High-throughput

0.426

High

1335721

MOT11
Monocarboxylate transporter 11

1

0

High-throughput

0.426

High

887226

CEBPA
CCAAT/enhancer-binding protein alpha

1

0

High-throughput

0.391

High

1326623

KLH36
Kelch-like protein 36

3

0

High-throughput

0.347

High

1434740

CHMP3
Charged multivesicular body protein 3

3

0

High-throughput

0.347

High

479747

GSTA2
Glutathione S-transferase A2

1

0

High-throughput

0.279

Low

472351

CFAH
Complement factor H

1

0

Small-scale

0.249

Low

1178381

CL16A
Protein CLEC16A

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025