Protein: IKBL1
NF-kappa-B inhibitor-like protein 1 (Inhibitor of kappa B-like protein) (I-kappa-B-like protein) (IkappaBL) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1)

Gene: IKBL1, NFKBIL1
Organism: Homo sapiens
Interactions: 96
UniProt ID: Q9UBC1

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0031665 - negative regulation of lipopolysaccharide-mediated signaling pathway
GO:0032088 - negative regulation of NF-kappaB transcription factor activity
GO:0032720 - negative regulation of tumor necrosis factor production

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

329799

ZRAB2
Zinc finger Ran-binding domain-containing protein 2

3

0

High-throughput

0.638

High

1394899

EAF1
ELL-associated factor 1

3

0

High-throughput

0.638

High

1145415

RNPS1
RNA-binding protein with serine-rich domain 1

3

0

High-throughput

0.622

High

1432373

PININ
Pinin

2

0

High-throughput

0.606

High

732729

ARRB2
Beta-arrestin-2

2

0

High-throughput

0.602

High

872041

PI42A
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha

2

0

High-throughput

0.602

High

1239686

JMJD6
Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6

2

0

High-throughput

0.602

High

1458280

NDK7
Nucleoside diphosphate kinase homolog 7

2

0

High-throughput

0.580

High

622698

TNR1A
Tumor necrosis factor receptor superfamily member 1A

2

1

High-throughput

0.574

High

1290791

ZCH18
Zinc finger CCCH domain-containing protein 18

2

1

High-throughput

0.574

High

1393327

SAHH3
Adenosylhomocysteinase 3

2

1

High-throughput

0.574

High

190172

TNC18
Trinucleotide repeat-containing gene 18 protein

1

1

High-throughput

0.536

High

630377

TNR1B
Tumor necrosis factor receptor superfamily member 1B

1

1

High-throughput

0.536

High

674358

BRD2
Bromodomain-containing protein 2

1

1

High-throughput

0.536

High

1186506

CHD9
Chromodomain-helicase-DNA-binding protein 9

1

2

High-throughput

0.536

High

1290313

KBTB6
Kelch repeat and BTB domain-containing protein 6

1

1

High-throughput

0.536

High

1358874

KBTB7
Kelch repeat and BTB domain-containing protein 7

1

1

High-throughput

0.536

High

1403520

MINT
Msx2-interacting protein

1

1

High-throughput

0.536

High

1404327

NP1L3
Nucleosome assembly protein 1-like 3

1

1

High-throughput

0.536

High

1439226

CHD8
Chromodomain-helicase-DNA-binding protein 8

1

2

High-throughput

0.536

High

1454483

CHD7
Chromodomain-helicase-DNA-binding protein 7

1

2

High-throughput

0.536

High

1458275

GPTC8
G patch domain-containing protein 8

1

1

High-throughput

0.536

High

1458276

ACINU
Apoptotic chromatin condensation inducer in the nucleus

1

1

High-throughput

0.536

High

1458278

SRRM2
Serine/arginine repetitive matrix protein 2

1

1

High-throughput

0.536

High

158514

RFXK
DNA-binding protein RFXANK

1

0

High-throughput

0.523

High

944583

GEMI4
Gem-associated protein 4

1

0

High-throughput

0.523

High

1434737

STEEP
STING ER exit protein

1

0

High-throughput

0.523

High

1437121

RM44
Large ribosomal subunit protein mL44

1

0

High-throughput

0.523

High

1458281

RT18B
Small ribosomal subunit protein mS40

1

0

High-throughput

0.523

High

122867

KIF2A
Kinesin-like protein KIF2A

1

0

High-throughput

0.513

High

134897

SAP18
Histone deacetylase complex subunit SAP18

1

0

High-throughput

0.513

High

175940

SET1A
Histone-lysine N-methyltransferase SETD1A

1

0

High-throughput

0.513

High

269814

CAPON
Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein

1

0

High-throughput

0.513

High

280854

PR40A
Pre-mRNA-processing factor 40 homolog A

1

0

High-throughput

0.513

High

284248

SRS10
Serine/arginine-rich splicing factor 10

1

0

High-throughput

0.513

High

572261

TRI27
Zinc finger protein RFP

1

0

High-throughput

0.513

High

604755

UBF1
Nucleolar transcription factor 1

1

0

High-throughput

0.513

High

889671

CLK2
Dual specificity protein kinase CLK2

1

0

High-throughput

0.513

High

932606

PTN5
Tyrosine-protein phosphatase non-receptor type 5

1

0

High-throughput

0.513

High

1007616

PRAME
Melanoma antigen preferentially expressed in tumors

1

0

High-throughput

0.513

High

1104998

PPIG
Peptidyl-prolyl cis-trans isomerase G

1

0

High-throughput

0.513

High

1134558

NOLC1
Nucleolar and coiled-body phosphoprotein 1

1

0

High-throughput

0.513

High

1141428

WDR43
WD repeat-containing protein 43

1

0

High-throughput

0.513

High

1211281

SNPC4
snRNA-activating protein complex subunit 4

1

0

High-throughput

0.513

High

1219062

RSBN1
Lysine-specific demethylase 9

1

0

High-throughput

0.513

High

1278823

HDGR2
Hepatoma-derived growth factor-related protein 2

1

0

High-throughput

0.513

High

1309720

WDR75
WD repeat-containing protein 75

1

0

High-throughput

0.513

High

1352459

UTP15
U3 small nucleolar RNA-associated protein 15 homolog

1

0

High-throughput

0.513

High

1370973

SNPC3
snRNA-activating protein complex subunit 3

1

0

High-throughput

0.513

High

1371556

USP9X
Ubiquitin carboxyl-terminal hydrolase 9X

1

0

High-throughput

0.513

High

1381608

UTP4
U3 small nucleolar RNA-associated protein 4 homolog

1

0

High-throughput

0.513

High

1390989

THOC1
THO complex subunit 1

1

0

High-throughput

0.513

High

1419382

SETD2
Histone-lysine N-methyltransferase SETD2

1

0

High-throughput

0.513

High

1436270

NOL11
Nucleolar protein 11

1

0

High-throughput

0.513

High

1437141

UBP42
Ubiquitin carboxyl-terminal hydrolase 42

1

0

High-throughput

0.513

High

1439047

CWC22
Pre-mRNA-splicing factor CWC22 homolog

1

0

High-throughput

0.513

High

1439432

SYF1
Pre-mRNA-splicing factor SYF1

1

0

High-throughput

0.513

High

1454053

CXXC1
CXXC-type zinc finger protein 1

1

0

High-throughput

0.513

High

1458272

AFF4
AF4/FMR2 family member 4

1

0

High-throughput

0.513

High

1458274

TSYL4
Testis-specific Y-encoded-like protein 4

1

0

High-throughput

0.513

High

126197

AP3B1
AP-3 complex subunit beta-1

1

1

High-throughput

0.489

High

230126

SAHH2
S-adenosylhomocysteine hydrolase-like protein 1

1

1

High-throughput

0.489

High

1103502

AP3B2
AP-3 complex subunit beta-2

1

1

High-throughput

0.489

High

1105883

TMED1
Transmembrane emp24 domain-containing protein 1

1

1

High-throughput

0.489

High

1346658

VANG1
Vang-like protein 1

1

1

High-throughput

0.489

High

1384145

ARRD3
Arrestin domain-containing protein 3

1

1

High-throughput

0.489

High

1458277

VANG2
Vang-like protein 2

1

1

High-throughput

0.489

High

1458279

TMED5
Transmembrane emp24 domain-containing protein 5

1

1

High-throughput

0.489

High

278989

PEX14
Peroxisomal membrane protein PEX14

1

0

High-throughput

0.480

High

1141340

BRD3
Bromodomain-containing protein 3

1

1

High-throughput

0.479

High

159899

DVL2
Segment polarity protein dishevelled homolog DVL-2

1

0

High-throughput

0.458

High

884411

UBE2A
Ubiquitin-conjugating enzyme E2 A

1

0

High-throughput

0.458

High

980476

H4
Histone H4

1

0

High-throughput

0.458

High

996374

EF1A1
Elongation factor 1-alpha 1

1

0

Small-scale

0.458

High

1062691

DHX9
ATP-dependent RNA helicase A

1

0

Small-scale

0.458

High

1357098

CATIN
Splicing factor Cactin

1

0

Small-scale

0.458

High

1458271

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

1458273

XPO7
Exportin-7

1

0

High-throughput

0.458

High

1449480

BMP2K
BMP-2-inducible protein kinase

1

0

Small-scale

0.438

High

1446680

LUC7L
Putative RNA-binding protein Luc7-like 1

4

0

High-throughput

0.366

High

1339402

GP156
Probable G-protein coupled receptor 156

2

0

High-throughput

0.328

High

1011209

RT22
Small ribosomal subunit protein mS22

1

0

High-throughput

0.285

High

1012643

RT34
Small ribosomal subunit protein mS34

1

0

High-throughput

0.285

High

1335533

CL18C
C-type lectin domain family 18 member C

1

0

High-throughput

0.282

High

1369562

CASPA
Caspase-10

1

0

High-throughput

0.282

High

1382484

PAQR1
Adiponectin receptor protein 1

1

0

High-throughput

0.282

High

1412339

SMAKA
Small membrane A-kinase anchor protein

1

0

High-throughput

0.282

High

718479

CD6
T-cell differentiation antigen CD6

1

0

High-throughput

0.279

Low

1242705

KLC3
Kinesin light chain 3

1

0

High-throughput

0.279

Low

1311044

SULF2
Extracellular sulfatase Sulf-2

1

0

High-throughput

0.279

Low

1315507

DAAF8
Dynein axonemal assembly factor 8

1

0

High-throughput

0.279

Low

1348983

ZCH10
Zinc finger CCHC domain-containing protein 10

1

0

High-throughput

0.279

Low

1400308

CC85A
Coiled-coil domain-containing protein 85A

1

0

High-throughput

0.279

Low

1280866

K2C1B
Keratin, type II cytoskeletal 1b

1

0

High-throughput

0.278

Low

608203

PYRG1
CTP synthase 1

1

0

Small-scale

0.249

Low

1194087

MINY4
Probable ubiquitin carboxyl-terminal hydrolase MINDY-4

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025