Protein: SEN34
tRNA-splicing endonuclease subunit Sen34 (EC 4.6.1.16) (Leukocyte receptor cluster member 5) (tRNA-intron endonuclease Sen34) (HsSen34)

Gene: SEN34, TSEN34
Organism: Homo sapiens
Interactions: 30
UniProt ID: Q9BSV6

Gene Ontology (top 5):
GO:0000213 - tRNA-intron lyase activity
GO:0000214 - tRNA-intron endonuclease complex
GO:0000379 - tRNA-type intron splice site recognition and cleavage
GO:0003676 - nucleic acid binding
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1335489

SEN2
tRNA-splicing endonuclease subunit Sen2

4

1

Small-scale

0.892

High

1358904

SEN15
tRNA-splicing endonuclease subunit Sen15

4

0

Small-scale

0.846

High

1371160

CLP1
Polyribonucleotide 5'-hydroxyl-kinase Clp1

2

0

Small-scale

0.585

High

436728

KPCB
Protein kinase C beta type

2

0

High-throughput

0.547

High

1287880

MTA70
N(6)-adenosine-methyltransferase catalytic subunit METTL3

1

0

High-throughput

0.513

High

431236

LA
Lupus La protein

1

1

High-throughput

0.489

High

1194340

LARP7
La-related protein 7

1

1

High-throughput

0.479

High

1380124

FBXW7
F-box/WD repeat-containing protein 7

1

1

Small-scale

0.479

High

1412928

FZR1
Fizzy-related protein homolog

1

1

High-throughput

0.479

High

1120313

HNRPD
Heterogeneous nuclear ribonucleoprotein D0

1

0

High-throughput

0.460

High

520335

ANDR
Androgen receptor

1

0

High-throughput

0.458

High

1280125

SEN54
tRNA-splicing endonuclease subunit Sen54

1

0

Small-scale

0.458

High

1405008

EYA3
Protein phosphatase EYA3

1

0

High-throughput

0.458

High

1412929

ASF1A
Histone chaperone ASF1A

1

0

High-throughput

0.458

High

1412927

FBW1B
F-box/WD repeat-containing protein 11

1

1

High-throughput

0.437

High

610455

PRS6A
26S proteasome regulatory subunit 6A

1

0

High-throughput

0.426

High

635374

IMDH1
Inosine-5'-monophosphate dehydrogenase 1

1

0

High-throughput

0.426

High

1110550

KCC2D
Calcium/calmodulin-dependent protein kinase type II subunit delta

1

0

High-throughput

0.426

High

1214185

LITD1
LINE-1 type transposase domain-containing protein 1

1

0

High-throughput

0.279

Low

294262

CD123
Translation initiation factor eIF2 assembly protein

1

0

High-throughput

0.249

Low

684026

PTN3
Tyrosine-protein phosphatase non-receptor type 3

1

0

High-throughput

0.249

Low

1338340

FBX22
F-box only protein 22

1

0

High-throughput

0.249

Low

1396789

SNX27
Sorting nexin-27

1

0

High-throughput

0.249

Low

1397377

CI072
Guanine nucleotide exchange factor C9orf72

1

0

High-throughput

0.249

Low

1412926

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.249

Low

142023

FCN1
Ficolin-1

1

0

Small-scale

0.238

Low

239185

ZNRD2
Protein ZNRD2

1

0

High-throughput

0.232

Low

388663

C1QA
Complement C1q subcomponent subunit A

1

0

High-throughput

0.232

Low

391436

FRIL
Ferritin light chain

1

0

High-throughput

0.232

Low

1156097

ZNF79
Zinc finger protein 79

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025