Protein: TM219
Insulin-like growth factor-binding protein 3 receptor (IGFBP-3R) (Transmembrane protein 219)

Gene: TM219, TMEM219
Organism: Homo sapiens
Interactions: 28
UniProt ID: Q86XT9

Gene Ontology (top 5):
GO:0005886 - plasma membrane
GO:0006915 - apoptotic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

380451

DQA1
HLA class II histocompatibility antigen, DQ alpha 1 chain

3

1

High-throughput

0.656

High

1143737

PON2
Serum paraoxonase/arylesterase 2

3

0

High-throughput

0.638

High

1294337

MCLN3
Mucolipin-3

3

0

High-throughput

0.638

High

1294342

ITM2B
Integral membrane protein 2B

3

0

High-throughput

0.638

High

733704

ACHA3
Neuronal acetylcholine receptor subunit alpha-3

2

1

High-throughput

0.628

High

1192252

ZACN
Ligand-gated cation channel ZACN

2

2

High-throughput

0.611

High

1294340

NRN1
Neuritin

2

0

High-throughput

0.602

High

1128913

I13R2
Interleukin-13 receptor subunit alpha-2

2

0

Small-scale

0.592

High

1249577

BTNL8
Butyrophilin-like protein 8

2

0

High-throughput

0.585

High

609882

IBP3
Insulin-like growth factor-binding protein 3

1

0

Small-scale

0.561

High

132621

UPK1A
Uroplakin-1a

1

1

High-throughput

0.536

High

851161

ACHA4
Neuronal acetylcholine receptor subunit alpha-4

1

1

High-throughput

0.536

High

1048796

ACHE
Acetylcholine receptor subunit epsilon

1

2

High-throughput

0.536

High

1254057

LRC55
Leucine-rich repeat-containing protein 55

1

1

High-throughput

0.536

High

1294336

LRC52
Leucine-rich repeat-containing protein 52

1

1

High-throughput

0.536

High

260902

RAMP3
Receptor activity-modifying protein 3

1

0

High-throughput

0.513

High

771789

SCN4A
Sodium channel protein type 4 subunit alpha

1

0

High-throughput

0.513

High

1180928

HFE
Hereditary hemochromatosis protein

1

0

High-throughput

0.513

High

1195442

NKAI1
Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 1

1

0

High-throughput

0.513

High

1294339

TTYH1
Protein tweety homolog 1

1

0

High-throughput

0.513

High

170850

CLGN
Calmegin

1

1

High-throughput

0.489

High

1294343

SHAN1
SH3 and multiple ankyrin repeat domains protein 1

1

0

High-throughput

0.480

High

1132384

CASP8
Caspase-8

1

0

Small-scale

0.458

High

97109

E9PMV2
Major histocompatibility complex, class II, DQ alpha 1

1

2

High-throughput

0.407

High

49792

CLRN2
Clarin-2

1

0

High-throughput

0.279

Low

1214095

DIK1A
Divergent protein kinase domain 1A

1

0

High-throughput

0.279

Low

1294338

TECT2
Tectonic-2

1

0

High-throughput

0.279

Low

1294341

S35C2
Solute carrier family 35 member C2

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025