Protein: DNPEP
Aspartyl aminopeptidase (EC 3.4.11.21)

Gene: DNPEP
Organism: Homo sapiens
Interactions: 99
UniProt ID: Q9ULA0

Gene Ontology (top 5):
GO:0004177 - aminopeptidase activity
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006508 - proteolysis

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1461473

DNPEP
Aspartyl aminopeptidase

3

4

High-throughput

0.861

High

1155401

RB11B
Ras-related protein Rab-11B

4

1

High-throughput

0.691

High

1348574

LNX1
E3 ubiquitin-protein ligase LNX

4

0

High-throughput

0.668

High

976651

RB11A
Ras-related protein Rab-11A

2

1

High-throughput

0.628

High

1368913

RBP56
TATA-binding protein-associated factor 2N

2

0

High-throughput

0.602

High

1460092

PP13
Galactoside-binding soluble lectin 13

2

0

High-throughput

0.602

High

1067827

EP300
Histone acetyltransferase p300

1

0

High-throughput

0.586

High

1461475

SCAF8
SR-related and CTD-associated factor 8

2

0

High-throughput

0.585

High

243267

PRKN
E3 ubiquitin-protein ligase parkin

2

0

High-throughput

0.559

High

1454400

PAK5
Serine/threonine-protein kinase PAK 5

1

0

Small-scale

0.554

High

946472

MTPN
Myotrophin

1

2

High-throughput

0.536

High

1439302

E41L5
Band 4.1-like protein 5

1

1

High-throughput

0.536

High

1447700

BIRC6
Dual E2 ubiquitin-conjugating enzyme/E3 ubiquitin-protein ligase BIRC6

1

1

High-throughput

0.536

High

639657

SAT1
Diamine acetyltransferase 1

1

0

High-throughput

0.518

High

1407131

MDFI
MyoD family inhibitor

1

0

High-throughput

0.518

High

300271

KT33A
Keratin, type I cuticular Ha3-I

1

3

High-throughput

0.515

High

300610

KRT36
Keratin, type I cuticular Ha6

1

3

High-throughput

0.515

High

331610

KIF4A
Chromosome-associated kinesin KIF4A

1

2

High-throughput

0.515

High

1146210

K1H1
Keratin, type I cuticular Ha1

1

3

High-throughput

0.515

High

1449298

KRT82
Keratin, type II cuticular Hb2

1

1

High-throughput

0.515

High

208422

RRP8
Ribosomal RNA-processing protein 8

1

0

High-throughput

0.513

High

239341

MYPT2
Protein phosphatase 1 regulatory subunit 12B

1

0

High-throughput

0.513

High

249795

DOK2
Docking protein 2

1

0

High-throughput

0.513

High

256515

TOM1
Target of Myb1 membrane trafficking protein

1

0

High-throughput

0.513

High

387153

TNNC2
Troponin C, skeletal muscle

1

0

High-throughput

0.513

High

465863

MSMB
Beta-microseminoprotein

1

0

High-throughput

0.513

High

1121994

ARHG7
Rho guanine nucleotide exchange factor 7

1

0

High-throughput

0.513

High

1414170

ISCA1
Iron-sulfur cluster assembly 1 homolog, mitochondrial

1

0

High-throughput

0.513

High

1436411

PAAT
ATPase PAAT

1

0

High-throughput

0.513

High

1460647

DBNL
Drebrin-like protein

1

0

High-throughput

0.493

High

1120893

DGCR6
Protein DGCR6

1

1

High-throughput

0.481

High

767369

MERL
Merlin

1

1

High-throughput

0.479

High

1107325

BIRC3
Baculoviral IAP repeat-containing protein 3

1

1

High-throughput

0.479

High

1260639

ASXL2
Putative Polycomb group protein ASXL2

1

2

High-throughput

0.479

High

1312445

ASXL1
Polycomb group protein ASXL1

1

2

High-throughput

0.479

High

1361257

DNJC9
DnaJ homolog subfamily C member 9

1

1

High-throughput

0.479

High

1421203

ASXL3
Putative Polycomb group protein ASXL3

1

2

High-throughput

0.479

High

1428415

MLP3B
Microtubule-associated protein 1 light chain 3 beta

1

2

High-throughput

0.479

High

1461479

KIF3A
Kinesin-like protein KIF3A

1

1

High-throughput

0.479

High

176098

KDM6B
Lysine-specific demethylase 6B

1

0

Small-scale

0.458

High

247179

TBCD4
TBC1 domain family member 4

1

0

High-throughput

0.458

High

316147

RECQ4
ATP-dependent DNA helicase Q4

1

0

High-throughput

0.458

High

346484

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

0

High-throughput

0.458

High

696838

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

888388

MCM2
DNA replication licensing factor MCM2

1

0

High-throughput

0.458

High

1089063

TP53B
TP53-binding protein 1

1

0

High-throughput

0.458

High

1094656

UBP4
Ubiquitin carboxyl-terminal hydrolase 4

1

0

Small-scale

0.458

High

1104941

XRCC4
DNA repair protein XRCC4

1

0

High-throughput

0.458

High

1138746

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

0

High-throughput

0.458

High

1256054

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.458

High

1312176

NELFD
Negative elongation factor C/D

1

0

High-throughput

0.458

High

1338428

FBX22
F-box only protein 22

1

0

High-throughput

0.458

High

1434209

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.458

High

1451313

PIHD1
PIH1 domain-containing protein 1

1

0

High-throughput

0.458

High

1459277

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

1460434

DS13B
Dual specificity protein phosphatase 13B

1

0

High-throughput

0.458

High

1461474

PADI4
Protein-arginine deiminase type-4

1

0

High-throughput

0.458

High

1461476

UN13A
Protein unc-13 homolog A

1

0

High-throughput

0.458

High

1461478

SAMH1
Deoxynucleoside triphosphate triphosphohydrolase SAMHD1

1

0

Small-scale

0.458

High

1461480

ASB3
Ankyrin repeat and SOCS box protein 3

1

0

High-throughput

0.458

High

116979

J3KPF9
Kinesin-like protein

1

1

High-throughput

0.445

High

142438

PEX7
Peroxisomal targeting signal 2 receptor

1

1

High-throughput

0.445

High

628667

CAP7
Azurocidin

1

1

High-throughput

0.445

High

1243529

CSAG1
Chondrosarcoma-associated gene 1 protein

1

1

High-throughput

0.445

High

1057034

FMR1
Fragile X messenger ribonucleoprotein 1

1

0

High-throughput

0.438

High

530557

TAU
Microtubule-associated protein tau

1

0

High-throughput

0.426

High

564549

CFTR
Cystic fibrosis transmembrane conductance regulator

1

0

High-throughput

0.426

High

1227687

A16L1
Autophagy-related protein 16-1

1

0

High-throughput

0.426

High

1315728

DND1
Dead end protein homolog 1

1

0

High-throughput

0.426

High

1449915

DDX28
Probable ATP-dependent RNA helicase DDX28

1

0

High-throughput

0.426

High

1461482

SIR4
NAD-dependent protein lipoamidase sirtuin-4, mitochondrial

1

0

High-throughput

0.426

High

1461483

X5DP20
DiGeorge syndrome critical region 6 isoform D

1

1

High-throughput

0.417

High

705603

GRN
Progranulin

1

1

High-throughput

0.407

High

1461481

CSAG2
Chondrosarcoma-associated gene 2/3 protein

1

1

High-throughput

0.407

High

1023989

EM55
55 kDa erythrocyte membrane protein

3

0

High-throughput

0.352

High

190729

MPPD1
Metallophosphoesterase domain-containing protein 1

3

0

High-throughput

0.347

High

1250334

ATL4
ADAMTS-like protein 4

1

0

High-throughput

0.282

High

270185

LRP3
Low-density lipoprotein receptor-related protein 3

1

0

High-throughput

0.279

Low

290791

SURF6
Surfeit locus protein 6

1

0

High-throughput

0.279

Low

1200343

ANR39
Ankyrin repeat domain-containing protein 39

1

0

High-throughput

0.279

Low

1211109

TMM69
Transmembrane protein 69

1

0

High-throughput

0.279

Low

1230815

ANR40
Ankyrin repeat domain-containing protein 40

1

0

High-throughput

0.279

Low

1251850

PPR21
Protein phosphatase 1 regulatory subunit 21

1

0

High-throughput

0.279

Low

1293311

LSR
Lipolysis-stimulated lipoprotein receptor

1

0

High-throughput

0.279

Low

1331803

F133A
Protein FAM133A

1

0

High-throughput

0.279

Low

1359400

DNJB3
DnaJ homolog subfamily B member 3

1

0

High-throughput

0.279

Low

1399528

LRC3B
Leucine-rich repeat-containing protein 3B

1

0

High-throughput

0.279

Low

1402875

GPX7
Glutathione peroxidase 7

1

0

High-throughput

0.279

Low

1450543

TMLH
Trimethyllysine dioxygenase, mitochondrial

1

0

High-throughput

0.279

Low

353622

AGR2
Anterior gradient protein 2 homolog

1

0

High-throughput

0.249

Low

704997

RBL1
Retinoblastoma-like protein 1

1

0

High-throughput

0.249

Low

1251619

HSDL2
Hydroxysteroid dehydrogenase-like protein 2

1

0

High-throughput

0.249

Low

1461477

AAR2
Protein AAR2 homolog

1

0

High-throughput

0.249

Low

261315

NSMA
Sphingomyelin phosphodiesterase 2

1

0

High-throughput

0.232

Low

330366

VENTX
Homeobox protein VENTX

1

0

High-throughput

0.232

Low

1104162

RM49
Large ribosomal subunit protein mL49

1

0

High-throughput

0.232

Low

1392422

SYMM
Methionine--tRNA ligase, mitochondrial

1

0

High-throughput

0.232

Low

1410889

MGME1
Mitochondrial genome maintenance exonuclease 1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025