Protein: TTC5
Tetratricopeptide repeat protein 5 (TPR repeat protein 5) (Stress-responsive activator of p300) (Protein Strap)

Gene: TTC5
Organism: Homo sapiens
Interactions: 50
UniProt ID: Q8N0Z6

Gene Ontology (top 5):
GO:0003677 - DNA binding
GO:0003682 - chromatin binding
GO:0005654 - nucleoplasm
GO:0005739 - mitochondrion
GO:0005759 - mitochondrial matrix

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1110498

KCC2D
Calcium/calmodulin-dependent protein kinase type II subunit delta

4

3

High-throughput

0.698

High

1110272

KCC2B
Calcium/calmodulin-dependent protein kinase type II subunit beta

3

3

High-throughput

0.675

High

1259336

TBA1A
Tubulin alpha-1A chain

3

4

High-throughput

0.667

High

457547

TBB5
Tubulin beta chain

3

6

High-throughput

0.662

High

1118520

TBB2A
Tubulin beta-2A chain

4

6

High-throughput

0.630

High

997026

TBA4A
Tubulin alpha-4A chain

2

4

High-throughput

0.628

High

1322489

TBB2B
Tubulin beta-2B chain

3

6

High-throughput

0.609

High

1110375

KCC2G
Calcium/calmodulin-dependent protein kinase type II subunit gamma

2

3

High-throughput

0.606

High

1322493

KCC2A
Calcium/calmodulin-dependent protein kinase type II subunit alpha

2

3

High-throughput

0.606

High

1239872

CAVN1
Caveolae-associated protein 1

2

0

High-throughput

0.580

High

1108602

TBB3
Tubulin beta-3 chain

2

6

High-throughput

0.574

High

1191877

TBB8
Tubulin beta-8 chain

2

6

High-throughput

0.574

High

1322487

TBA1C
Tubulin alpha-1C chain

2

5

High-throughput

0.574

High

1322490

T11L1
T-complex protein 11-like protein 1

2

1

High-throughput

0.574

High

1067500

EP300
Histone acetyltransferase p300

2

0

Small-scale

0.559

High

997421

TBB4B
Tubulin beta-4B chain

1

6

High-throughput

0.536

High

1322480

JMY
Junction-mediating and -regulatory protein

1

0

Small-scale

0.529

High

642103

ODBB
2-oxoisovalerate dehydrogenase subunit beta, mitochondrial

1

0

High-throughput

0.513

High

1091071

FOXF2
Forkhead box protein F2

1

0

High-throughput

0.513

High

1322492

MTUS1
Microtubule-associated tumor suppressor 1

1

0

High-throughput

0.513

High

1322479

T11L2
T-complex protein 11-like protein 2

1

1

High-throughput

0.489

High

396485

ESR1
Estrogen receptor

1

2

Small-scale

0.479

High

404217

GCR
Glucocorticoid receptor

1

2

Small-scale

0.479

High

520199

ANDR
Androgen receptor

1

2

Small-scale

0.479

High

1322488

TBB6
Tubulin beta-6 chain

1

6

High-throughput

0.470

High

242252

PRKN
E3 ubiquitin-protein ligase parkin

1

0

High-throughput

0.458

High

372548

MYC
Myc proto-oncogene protein

1

0

Small-scale

0.458

High

831049

CCNF
Cyclin-F

1

0

High-throughput

0.458

High

1026460

HSF1
Heat shock factor protein 1

1

0

Small-scale

0.458

High

1113658

CUL3
Cullin-3

1

0

High-throughput

0.458

High

1155532

EZH2
Histone-lysine N-methyltransferase EZH2

1

0

High-throughput

0.458

High

1187792

AL1L2
Mitochondrial 10-formyltetrahydrofolate dehydrogenase

1

0

High-throughput

0.458

High

1291060

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

0

High-throughput

0.458

High

1322483

CSN5
COP9 signalosome complex subunit 5

1

0

High-throughput

0.458

High

1322495

KLK5
Kallikrein-5

1

0

High-throughput

0.458

High

1322478

STPG2
Sperm-tail PG-rich repeat-containing protein 2

3

0

High-throughput

0.347

High

1322486

PLPR2
Phospholipid phosphatase-related protein type 2

3

0

High-throughput

0.347

High

162231

CDIPT
CDP-diacylglycerol--inositol 3-phosphatidyltransferase

2

0

High-throughput

0.328

High

1322481

NLGN2
Neuroligin-2

2

0

High-throughput

0.328

High

1322484

ZBTB9
Zinc finger and BTB domain-containing protein 9

2

0

High-throughput

0.328

High

290378

RFPL2
Ret finger protein-like 2

2

0

High-throughput

0.318

High

1275996

HDX
Highly divergent homeobox

2

0

High-throughput

0.316

High

1322485

DDT4L
DNA damage-inducible transcript 4-like protein

2

0

High-throughput

0.316

High

1322491

GOG6A
Golgin subfamily A member 6A

2

0

High-throughput

0.316

High

1322496

BACE2
Beta-secretase 2

1

0

High-throughput

0.279

Low

1322482

F216A
Protein FAM216A

1

0

High-throughput

0.269

Low

1254594

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

1322494

AAR2
Protein AAR2 homolog

1

0

High-throughput

0.249

Low

1198597

NCBP3
Nuclear cap-binding protein subunit 3

1

0

High-throughput

0.232

Low

1316827

OFCC1
Orofacial cleft 1 candidate gene 1 protein

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025