Protein: IL27B
Interleukin-27 subunit beta (IL-27 subunit beta) (IL-27B) (Epstein-Barr virus-induced gene 3 protein) (EBV-induced gene 3 protein)

Gene: IL27B, EBI3
Organism: Homo sapiens
Interactions: 28
UniProt ID: Q14213

Gene Ontology (top 5):
GO:0004896 - cytokine receptor activity
GO:0005125 - cytokine activity
GO:0005576 - extracellular region
GO:0005615 - extracellular space
GO:0005788 - endoplasmic reticulum lumen

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1051924

KPCD
Protein kinase C delta type

1

8

High-throughput

0.691

High

507962

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

2

High-throughput

0.647

High

607371

HLAG
HLA class I histocompatibility antigen, alpha chain G

1

4

Small-scale

0.618

High

963506

B2MG
Beta-2-microglobulin [Cleaved into: Beta-2-microglobulin form pI 5.3]

1

8

Small-scale

0.618

High

1124173

LIRB2
Leukocyte immunoglobulin-like receptor subfamily B member 2

1

16

Small-scale

0.618

High

1124175

LIRB1
Leukocyte immunoglobulin-like receptor subfamily B member 1

1

15

Small-scale

0.618

High

712730

IL12A
Interleukin-12 subunit alpha

2

3

Small-scale

0.584

High

1124174

IL27A
Interleukin-27 subunit alpha

2

2

Small-scale

0.584

High

457437

TBB5
Tubulin beta chain

1

7

High-throughput

0.575

High

1124171

ARMC8
Armadillo repeat-containing protein 8

1

1

High-throughput

0.536

High

1124170

MAEA
E3 ubiquitin-protein transferase MAEA

1

0

High-throughput

0.513

High

1124179

ZMY19
Zinc finger MYND domain-containing protein 19

1

0

High-throughput

0.513

High

1014512

SMAD3
Mothers against decapentaplegic homolog 3

1

2

High-throughput

0.508

High

445177

S10A6
Protein S100-A6

1

2

Small-scale

0.501

High

682485

S100P
Protein S100-P

1

2

Small-scale

0.501

High

207816

ZZEF1
Zinc finger ZZ-type and EF-hand domain-containing protein 1

1

4

High-throughput

0.489

High

1124168

HECD3
E3 ubiquitin-protein ligase HECTD3

1

10

High-throughput

0.489

High

698651

CALX
Calnexin

1

6

Small-scale

0.479

High

1124169

I27RA
Interleukin-27 receptor subunit alpha

1

19

Small-scale

0.479

High

1124178

CA054
Uncharacterized protein C1orf54

1

1

High-throughput

0.445

High

1124172

HDBP1
Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1

1

0

High-throughput

0.426

High

170761

CLGN
Calmegin

1

6

High-throughput

0.407

High

258877

DNJA2
DnaJ homolog subfamily A member 2

1

3

High-throughput

0.407

High

926766

VMAT1
Chromaffin granule amine transporter

1

3

High-throughput

0.407

High

1124181

FBX6
F-box only protein 6

1

8

High-throughput

0.407

High

1124180

MDFI
MyoD family inhibitor

1

0

High-throughput

0.282

High

1124176

ZCH10
Zinc finger CCHC domain-containing protein 10

1

0

High-throughput

0.232

Low

1124177

KBTB7
Kelch repeat and BTB domain-containing protein 7

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025