Protein: FRAT2
GSK-3-binding protein FRAT2 (Frequently rearranged in advanced T-cell lymphomas 2) (FRAT-2)

Gene: FRAT2
Organism: Homo sapiens
Interactions: 27
UniProt ID: O75474

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0046825 - regulation of protein export from nucleus
GO:0060070 - canonical Wnt signaling pathway

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

282983

GSK3B
Glycogen synthase kinase-3 beta

3

3

Small-scale

0.871

High

282982

GSK3A
Glycogen synthase kinase-3 alpha

1

3

High-throughput

0.691

High

224065

BUB1
Mitotic checkpoint serine/threonine-protein kinase BUB1

1

0

High-throughput

0.663

High

282972

EGFR
Epidermal growth factor receptor

1

1

High-throughput

0.541

High

282973

RASN
GTPase NRas

1

2

High-throughput

0.541

High

282974

RASK
GTPase KRas

1

2

High-throughput

0.541

High

282975

ERBB2
Receptor tyrosine-protein kinase erbB-2

1

1

High-throughput

0.541

High

282979

MLH1
DNA mismatch repair protein Mlh1

1

1

High-throughput

0.541

High

282994

MLH3
DNA mismatch repair protein Mlh3

1

1

High-throughput

0.541

High

282987

CE170
Centrosomal protein of 170 kDa

1

1

High-throughput

0.536

High

282976

CRCM
Colorectal mutant cancer protein

1

0

High-throughput

0.518

High

282978

CTNA1
Catenin alpha-1

1

0

High-throughput

0.518

High

282985

PTN12
Tyrosine-protein phosphatase non-receptor type 12

1

0

High-throughput

0.518

High

282986

FP100
Fanconi anemia core complex-associated protein 100

1

0

High-throughput

0.513

High

282988

SAMD1
Sterile alpha motif domain-containing protein 1

1

0

High-throughput

0.513

High

282990

TP4AP
Short transient receptor potential channel 4-associated protein

1

0

High-throughput

0.513

High

282991

SYNE2
Nesprin-2

1

0

High-throughput

0.513

High

282992

RIPL2
RILP-like protein 2

1

0

High-throughput

0.513

High

282995

DACH1
Dachshund homolog 1

1

0

High-throughput

0.513

High

282996

PUS1
Pseudouridylate synthase 1 homolog

1

0

High-throughput

0.513

High

282980

CDN2A
Cyclin-dependent kinase inhibitor 2A

1

0

High-throughput

0.460

High

172330

XPO1
Exportin-1

1

0

High-throughput

0.458

High

282981

SOX2
Transcription factor SOX-2

1

0

High-throughput

0.458

High

282989

ARF
Tumor suppressor ARF

1

0

High-throughput

0.438

High

282993

C170L
Cep170-like protein

1

1

High-throughput

0.407

High

282977

S10A2
Protein S100-A2

1

0

High-throughput

0.279

Low

282984

FCGRN
IgG receptor FcRn large subunit p51

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025