Protein: TP4AP
Short transient receptor potential channel 4-associated protein (Trp4-associated protein) (Trpc4-associated protein) (Protein TAP1) (TNF-receptor ubiquitous scaffolding/signaling protein) (Protein TRUSS)

Gene: TP4AP, TRPC4AP
Organism: Homo sapiens
Interactions: 113
UniProt ID: Q8TEL6

Gene Ontology (top 5):
GO:0005262 - calcium channel activity
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0006511 - ubiquitin-dependent protein catabolic process
GO:0016567 - protein ubiquitination

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1114955

CUL4A
Cullin-4A

8

1

Small-scale

0.748

High

1115316

CUL4B
Cullin-4B

5

1

Small-scale

0.718

High

1157829

DDB1
DNA damage-binding protein 1

8

0

Small-scale

0.717

High

1279874

RBBP6
E3 ubiquitin-protein ligase RBBP6

3

1

High-throughput

0.662

High

1352893

DDA1
DET1- and DDB1-associated protein 1

4

0

Small-scale

0.661

High

1352879

CSN5
COP9 signalosome complex subunit 5

3

1

High-throughput

0.656

High

862917

IQGA1
Ras GTPase-activating-like protein IQGAP1

2

0

High-throughput

0.602

High

1060552

KLC1
Kinesin light chain 1

2

0

High-throughput

0.602

High

1153203

HERC1
Probable E3 ubiquitin-protein ligase HERC1

2

0

High-throughput

0.602

High

1153775

NCOA1
Nuclear receptor coactivator 1

2

0

High-throughput

0.602

High

1156557

CCDC6
Coiled-coil domain-containing protein 6

2

0

High-throughput

0.602

High

1311006

SULF2
Extracellular sulfatase Sulf-2

2

0

High-throughput

0.602

High

1352895

UNKL
Putative E3 ubiquitin-protein ligase UNKL

2

0

High-throughput

0.602

High

1352896

E41L5
Band 4.1-like protein 5

2

0

High-throughput

0.602

High

167935

IKKB
Inhibitor of nuclear factor kappa-B kinase subunit beta

2

1

Small-scale

0.601

High

1352883

VTI1A
Vesicle transport through interaction with t-SNAREs homolog 1A

2

1

High-throughput

0.601

High

622643

TNR1A
Tumor necrosis factor receptor superfamily member 1A

2

0

Small-scale

0.598

High

1090813

TRAF2
TNF receptor-associated factor 2

2

0

Small-scale

0.585

High

376998

ANF
Natriuretic peptides A

2

0

High-throughput

0.576

High

1094383

CSN1
COP9 signalosome complex subunit 1

2

0

High-throughput

0.576

High

1352891

SCAFB
Protein SCAF11

2

1

High-throughput

0.574

High

372661

MYC
Myc proto-oncogene protein

2

0

Small-scale

0.559

High

967872

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

1

0

Small-scale

0.537

High

875728

PRC2A
Protein PRRC2A

1

1

High-throughput

0.536

High

1352906

PRC2C
Protein PRRC2C

1

1

High-throughput

0.536

High

177912

IKKA
Inhibitor of nuclear factor kappa-B kinase subunit alpha

1

1

Small-scale

0.515

High

269795

CAPON
Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein

1

0

High-throughput

0.513

High

282990

FRAT2
GSK-3-binding protein FRAT2

1

0

High-throughput

0.513

High

333500

MPZL1
Myelin protein zero-like protein 1

1

0

High-throughput

0.513

High

505655

DC8L2
DDB1- and CUL4-associated factor 8-like protein 2

1

0

High-throughput

0.513

High

557399

SRC
Proto-oncogene tyrosine-protein kinase Src

1

0

High-throughput

0.513

High

1025937

NDP
Norrin

1

0

High-throughput

0.513

High

1093389

TRI32
E3 ubiquitin-protein ligase TRIM32

1

0

High-throughput

0.513

High

1325060

PLCD3
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3

1

0

High-throughput

0.513

High

1352907

PCDBB
Protocadherin beta-11

1

0

High-throughput

0.513

High

1352884

CHM4C
Charged multivesicular body protein 4c

1

2

High-throughput

0.508

High

1109633

RIPK1
Receptor-interacting serine/threonine-protein kinase 1

1

0

Small-scale

0.493

High

1150551

TRADD
Tumor necrosis factor receptor type 1-associated DEATH domain protein

1

0

Small-scale

0.493

High

1153072

TAB1
TGF-beta-activated kinase 1 and MAP3K7-binding protein 1

1

0

High-throughput

0.486

High

138242

PSDE
26S proteasome non-ATPase regulatory subunit 14

1

1

High-throughput

0.479

High

424232

S10A8
Protein S100-A8

1

2

High-throughput

0.479

High

445035

S10A9
Protein S100-A9

1

3

High-throughput

0.479

High

480863

LEG1
Galectin-1

1

1

High-throughput

0.479

High

652368

TGM1
Protein-glutamine gamma-glutamyltransferase K

1

1

High-throughput

0.479

High

724607

S10A7
Protein S100-A7

1

3

High-throughput

0.479

High

878234

TRPC1
Short transient receptor potential channel 1

1

2

Small-scale

0.479

High

1352886

S10AG
Protein S100-A16

1

3

High-throughput

0.479

High

1352899

TRPC4
Short transient receptor potential channel 4

1

2

Small-scale

0.479

High

1352903

TRPC5
Short transient receptor potential channel 5

1

2

Small-scale

0.479

High

1352908

NEMO
NF-kappa-B essential modulator

1

1

Small-scale

0.479

High

144022

P3C2B
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta

1

0

High-throughput

0.458

High

159378

DVL1
Segment polarity protein dishevelled homolog DVL-1

1

0

High-throughput

0.458

High

320732

UBXN7
UBX domain-containing protein 7

1

0

High-throughput

0.458

High

404259

GCR
Glucocorticoid receptor

1

0

High-throughput

0.458

High

423681

ARGI1
Arginase-1

1

0

High-throughput

0.458

High

456255

CATD
Cathepsin D

1

0

High-throughput

0.458

High

587747

DESP
Desmoplakin

1

0

High-throughput

0.458

High

637652

FLNA
Filamin-A

1

0

High-throughput

0.458

High

839598

HUTH
Histidine ammonia-lyase

1

0

High-throughput

0.458

High

957452

UBC12
NEDD8-conjugating enzyme Ubc12

1

0

High-throughput

0.458

High

983901

RBX1
E3 ubiquitin-protein ligase RBX1

1

0

Small-scale

0.458

High

1030480

FABP5
Fatty acid-binding protein 5

1

0

High-throughput

0.458

High

1101859

SKP2
S-phase kinase-associated protein 2

1

0

Small-scale

0.458

High

1352878

DCAF4
DDB1- and CUL4-associated factor 4

1

0

High-throughput

0.458

High

1352880

GLMN
Glomulin

1

0

High-throughput

0.458

High

1352888

DOCK6
Dedicator of cytokinesis protein 6

1

0

High-throughput

0.458

High

1352900

CSN7A
COP9 signalosome complex subunit 7a

1

0

High-throughput

0.458

High

1352909

S23IP
SEC23-interacting protein

1

0

High-throughput

0.458

High

221871

CHM2A
Charged multivesicular body protein 2a

1

1

High-throughput

0.457

High

1273175

CHM1B
Charged multivesicular body protein 1b

1

2

High-throughput

0.457

High

1352887

CHMP6
Charged multivesicular body protein 6

1

2

High-throughput

0.457

High

1352898

CHMP5
Charged multivesicular body protein 5

1

3

High-throughput

0.457

High

1352901

VTI1B
Vesicle transport through interaction with t-SNAREs homolog 1B

1

1

High-throughput

0.445

High

67563

MYH7B
Myosin-7B

1

1

High-throughput

0.437

High

469146

SRPRA
Signal recognition particle receptor subunit alpha

1

1

High-throughput

0.437

High

868746

LEG7
Galectin-7

1

1

High-throughput

0.437

High

1062270

TGM3
Protein-glutamine gamma-glutamyltransferase E

1

1

High-throughput

0.437

High

1352904

TR150
Thyroid hormone receptor-associated protein 3

1

1

High-throughput

0.437

High

640234

EPHA1
Ephrin type-A receptor 1

1

0

High-throughput

0.426

High

1047847

TLE1
Transducin-like enhancer protein 1

1

0

High-throughput

0.426

High

1272495

CSN6
COP9 signalosome complex subunit 6

1

0

High-throughput

0.426

High

1272855

TAOK1
Serine/threonine-protein kinase TAO1

1

0

High-throughput

0.426

High

1352882

TTC17
Tetratricopeptide repeat protein 17

1

0

High-throughput

0.426

High

567929

PRG2
Bone marrow proteoglycan

3

0

High-throughput

0.347

High

65786

SMHD1
Structural maintenance of chromosomes flexible hinge domain-containing protein 1

3

0

High-throughput

0.345

High

207757

MCES
mRNA cap guanine-N(7) methyltransferase

2

0

High-throughput

0.328

High

1165373

ODAPH
Odontogenesis associated phosphoprotein

2

0

High-throughput

0.328

High

1231219

KDM4D
Lysine-specific demethylase 4D

2

0

High-throughput

0.328

High

1352890

INT14
Integrator complex subunit 14

2

0

High-throughput

0.328

High

49943

LNP1
Leukemia NUP98 fusion partner 1

1

0

High-throughput

0.279

Low

665934

IBP6
Insulin-like growth factor-binding protein 6

1

0

High-throughput

0.279

Low

1103102

MFAP5
Microfibrillar-associated protein 5

1

0

High-throughput

0.279

Low

1211554

F120S
Uncharacterized protein FAM120AOS

1

0

High-throughput

0.279

Low

1251240

LBX2
Transcription factor LBX2

1

0

High-throughput

0.279

Low

1340892

MB3L2
Methyl-CpG-binding domain protein 3-like 2

1

0

High-throughput

0.279

Low

1352889

COX42
Cytochrome c oxidase subunit 4 isoform 2, mitochondrial

1

0

High-throughput

0.279

Low

1352892

MMTA2
Multiple myeloma tumor-associated protein 2

1

0

High-throughput

0.279

Low

1352894

SETD2
Histone-lysine N-methyltransferase SETD2

1

0

High-throughput

0.279

Low

1007836

IRX1
Iroquois-class homeodomain protein IRX-1

1

0

High-throughput

0.269

Low

1338054

DR9C7
Short-chain dehydrogenase/reductase family 9C member 7

1

0

High-throughput

0.269

Low

346667

TTC4
Tetratricopeptide repeat protein 4

1

0

High-throughput

0.249

Low

943279

RBM11
Splicing regulator RBM11

1

0

High-throughput

0.249

Low

963211

LYSC
Lysozyme C

1

0

High-throughput

0.249

Low

1010676

DCD
Dermcidin

1

0

High-throughput

0.249

Low

1213787

KPRP
Keratinocyte proline-rich protein

1

0

High-throughput

0.249

Low

1213873

KPLCE
Protein KPLCE

1

0

High-throughput

0.249

Low

1352881

TP4A1
Protein tyrosine phosphatase type IVA 1

1

0

High-throughput

0.249

Low

1352885

KBP
KIF-binding protein

1

0

High-throughput

0.249

Low

1352897

CALL5
Calmodulin-like protein 5

1

0

High-throughput

0.249

Low

1352902

XPO7
Exportin-7

1

0

High-throughput

0.249

Low

1352905

TRRAP
Transformation/transcription domain-associated protein

1

0

High-throughput

0.249

Low

511041

PNM6A
Paraneoplastic antigen-like protein 6A

1

0

High-throughput

0.232

Low

1108626

TBB3
Tubulin beta-3 chain

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025