Protein: PLCG2
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 (EC 3.1.4.11) (Phosphoinositide phospholipase C-gamma-2) (Phospholipase C-gamma-2) (PLC-gamma-2)

Gene: PLCG2
Organism: Mus musculus
Interactions: 41
UniProt ID: Q8CIH5

Gene Ontology (top 5):
GO:0001775 - cell activation
GO:0001784 - phosphotyrosine residue binding
GO:0001878 - response to yeast
GO:0002092 - positive regulation of receptor internalization
GO:0002223 - stimulatory C-type lectin receptor signaling pathway

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

452188

CSF1R
Macrophage colony-stimulating factor 1 receptor

1

20

Small-scale

0.680

High

540274

EPOR
Erythropoietin receptor

1

7

Small-scale

0.665

High

639456

LYN
Tyrosine-protein kinase Lyn

1

17

Small-scale

0.665

High

557351

BLK
Tyrosine-protein kinase Blk

1

17

Small-scale

0.618

High

729760

BTK
Tyrosine-protein kinase BTK

1

16

Small-scale

0.618

High

763400

FYN
Tyrosine-protein kinase Fyn

1

17

Small-scale

0.618

High

815739

KSYK
Tyrosine-protein kinase SYK

1

20

Small-scale

0.618

High

1141452

MERTK
Tyrosine-protein kinase Mer

1

16

Small-scale

0.618

High

1208607

BLNK
B-cell linker protein

1

7

Small-scale

0.618

High

506793

FINC
Fibronectin

1

1

High-throughput

0.590

High

970656

SOS2
Son of sevenless homolog 2

1

6

High-throughput

0.590

High

1208606

SHIP1
Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1

1

3

High-throughput

0.590

High

956457

NBR1
Next to BRCA1 gene 1 protein

1

0

High-throughput

0.560

High

515672

ITB2
Integrin beta-2

1

2

High-throughput

0.501

High

1207604

A16L1
Autophagy-related protein 16-1

1

1

High-throughput

0.479

High

996440

RUNX2
Runt-related transcription factor 2

1

0

Small-scale

0.458

High

1193767

FACD2
Fanconi anemia group D2 protein homolog

1

0

High-throughput

0.458

High

250716

E41L2
Band 4.1-like protein 2

1

1

High-throughput

0.457

High

525137

GELS
Gelsolin

1

4

High-throughput

0.457

High

956187

BACH2
Transcription regulator protein BACH2

1

2

High-throughput

0.457

High

1141502

DVL2
Segment polarity protein dishevelled homolog DVL-2

1

1

High-throughput

0.457

High

1143604

TRI27
Zinc finger protein RFP

1

2

High-throughput

0.457

High

1143722

SPTB2
Spectrin beta chain, non-erythrocytic 1

1

2

High-throughput

0.457

High

1145226

ZBT7B
Zinc finger and BTB domain-containing protein 7B

1

2

High-throughput

0.457

High

1207250

FLNA
Filamin-A

1

5

High-throughput

0.457

High

1208603

ERRFI
ERBB receptor feedback inhibitor 1

1

1

High-throughput

0.457

High

1208609

SPY2
Protein sprouty homolog 2

1

2

High-throughput

0.457

High

1208610

PDC6I
Programmed cell death 6-interacting protein

1

2

High-throughput

0.457

High

192708

HAX1
HCLS1-associated protein X-1

1

0

High-throughput

0.438

High

222612

REPS1
RalBP1-associated Eps domain-containing protein 1

1

0

High-throughput

0.438

High

621307

CRYAB
Alpha-crystallin B chain

1

0

High-throughput

0.438

High

768498

CAP1
Adenylyl cyclase-associated protein 1

1

0

High-throughput

0.438

High

604045

TAL1
T-cell acute lymphocytic leukemia protein 1 homolog

1

2

High-throughput

0.437

High

250825

FHL2
Four and a half LIM domains protein 2

1

1

High-throughput

0.417

High

1207286

TOX4
TOX high mobility group box family member 4

1

3

High-throughput

0.417

High

1208602

SH3K1
SH3 domain-containing kinase-binding protein 1

1

2

High-throughput

0.417

High

1208608

PHC2
Polyhomeotic-like protein 2

1

1

High-throughput

0.417

High

850520

DYLT1
Dynein light chain Tctex-type 1

1

0

High-throughput

0.238

Low

855283

UCK1
Uridine-cytidine kinase 1

1

0

High-throughput

0.238

Low

1208604

Q9CZL0
GOLD domain-containing protein

1

0

High-throughput

0.238

Low

1208605

NDC80
Kinetochore protein NDC80 homolog

1

0

High-throughput

0.238

Low


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Last updated: 15 Jul 2024