Protein: LYN
Tyrosine-protein kinase Lyn (EC 2.7.10.2) (V-yes-1 Yamaguchi sarcoma viral related oncogene homolog) (p53Lyn) (p56Lyn)

Gene: LYN
Organism: Mus musculus
Interactions: 40
UniProt ID: P25911

Gene Ontology (top 5):
GO:0000077 - DNA damage checkpoint signaling
GO:0001782 - B cell homeostasis
GO:0001817 - regulation of cytokine production
GO:0001933 - negative regulation of protein phosphorylation
GO:0002244 - hematopoietic progenitor cell differentiation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

639438

HCLS1
Hematopoietic lineage cell-specific protein

2

20

Small-scale

0.807

High

639443

PHAG1
Phosphoprotein associated with glycosphingolipid-enriched microdomains 1

1

12

Small-scale

0.740

High

639451

EFS
Embryonal Fyn-associated substrate

2

20

Small-scale

0.704

High

610545

CBL
E3 ubiquitin-protein ligase CBL

4

20

Small-scale

0.676

High

639456

PLCG2
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2

1

17

Small-scale

0.665

High

639464

GAB2
GRB2-associated-binding protein 2

1

20

Small-scale

0.646

High

193089

FYB1
FYN-binding protein 1

1

17

Small-scale

0.618

High

639435

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

1

20

Small-scale

0.618

High

639436

PTN6
Tyrosine-protein phosphatase non-receptor type 6

1

20

Small-scale

0.618

High

639437

KSYK
Tyrosine-protein kinase SYK

1

20

Small-scale

0.618

High

639441

DOK1
Docking protein 1

1

20

Small-scale

0.618

High

639444

SKAP2
Src kinase-associated phosphoprotein 2

1

20

Small-scale

0.618

High

639445

SH21C
SH2 domain-containing protein 1B2

1

19

Small-scale

0.618

High

639459

Q91YX7
RAS p21 protein activator 1

1

20

Small-scale

0.618

High

639462

CLNK
Cytokine-dependent hematopoietic cell linker

1

20

Small-scale

0.618

High

639458

ANR54
Ankyrin repeat domain-containing protein 54

1

15

High-throughput

0.590

High

540265

EPOR
Erythropoietin receptor

1

18

Small-scale

0.575

High

250950

DOK2
Docking protein 2

1

20

Small-scale

0.527

High

639440

IRS2
Insulin receptor substrate 2

1

20

Small-scale

0.527

High

639446

SRC8
Src substrate cortactin

1

20

Small-scale

0.527

High

639448

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

20

Small-scale

0.527

High

639449

DBNL
Drebrin-like protein

1

20

Small-scale

0.527

High

639447

KHDR1
KH domain-containing, RNA-binding, signal transduction-associated protein 1

1

20

Small-scale

0.501

High

192581

TNR11
Tumor necrosis factor receptor superfamily member 11A

1

10

Small-scale

0.500

High

101424

F8VPR5
histone acetyltransferase

1

15

Small-scale

0.479

High

102811

G3X9H5
Huntingtin

1

4

High-throughput

0.479

High

515982

CD79A
B-cell antigen receptor complex-associated protein alpha chain

1

2

Small-scale

0.479

High

594156

FCERB
High affinity immunoglobulin epsilon receptor subunit beta

1

3

Small-scale

0.479

High

639442

LIRB3
Leukocyte immunoglobulin-like receptor subfamily B member 3

1

20

Small-scale

0.479

High

639450

ITA2
Integrin alpha-2

1

6

Small-scale

0.479

High

639452

FCRL5
Fc receptor-like protein 5

1

19

Small-scale

0.479

High

639453

CLC7A
C-type lectin domain family 7 member A

1

3

Small-scale

0.479

High

639454

FACD2
Fanconi anemia group D2 protein homolog

1

4

High-throughput

0.479

High

639455

A16L1
Autophagy-related protein 16-1

1

12

High-throughput

0.479

High

82734

B9EKI5
E3 ubiquitin-protein ligase CBL

1

20

High-throughput

0.457

High

639439

HNRPK
Heterogeneous nuclear ribonucleoprotein K

1

12

High-throughput

0.457

High

639463

KLF5
Krueppel-like factor 5

1

5

High-throughput

0.457

High

639461

SRCN1
SRC kinase signaling inhibitor 1

1

8

High-throughput

0.445

High

639460

Q9JM08
Histone deacetylase

1

1

Small-scale

0.437

High

639457

RBM12
RNA-binding protein 12

1

7

High-throughput

0.417

High


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Last updated: 15 Jul 2024