Protein: R3GEF
Guanine nucleotide exchange factor for Rab-3A (Rab-3A-interacting-like protein 1) (Rab3A-interacting-like protein 1) (Rabin3-like 1)

Gene: R3GEF, RAB3IL1
Organism: Homo sapiens
Interactions: 59
UniProt ID: Q8TBN0

Gene Ontology (top 5):
GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005829 - cytosol
GO:0006887 - exocytosis
GO:0015031 - protein transport
GO:0042802 - identical protein binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1252963

RAB3I
Rab-3A-interacting protein

7

2

High-throughput

0.975

High

1252956

R3GEF
Guanine nucleotide exchange factor for Rab-3A

3

2

High-throughput

0.860

High

894777

RAB8A
Ras-related protein Rab-8A

3

3

Small-scale

0.849

High

914234

RB11A
Ras-related protein Rab-11A

3

1

High-throughput

0.845

High

591481

RAB3A
Ras-related protein Rab-3A

2

7

High-throughput

0.783

High

1119001

AMOT
Angiomotin

3

1

High-throughput

0.667

High

255252

LIPA3
Liprin-alpha-3

3

0

High-throughput

0.638

High

1252960

OPTN
Optineurin

3

0

High-throughput

0.638

High

1252961

ATG4C
Cysteine protease ATG4C

3

0

High-throughput

0.638

High

1238425

TM102
Transmembrane protein 102

4

3

High-throughput

0.633

High

1173002

NUD18
8-oxo-dGDP phosphatase NUDT18

2

0

High-throughput

0.613

High

1189370

NT2NA
Notch homolog 2 N-terminal-like protein A

3

1

High-throughput

0.609

High

280663

KRT34
Keratin, type I cuticular Ha4

2

2

High-throughput

0.606

High

1198822

TTC7B
Tetratricopeptide repeat protein 7B

2

1

High-throughput

0.606

High

1124564

ODFP2
Outer dense fiber protein 2

2

0

High-throughput

0.585

High

1252957

PPIL4
Peptidyl-prolyl cis-trans isomerase-like 4

2

0

High-throughput

0.585

High

253122

HSF2B
Heat shock factor 2-binding protein

2

0

High-throughput

0.580

High

1083964

STX1A
Syntaxin-1A

2

0

High-throughput

0.580

High

1252967

CN119
Uncharacterized protein C14orf119

2

0

High-throughput

0.580

High

1252972

COG6
Conserved oligomeric Golgi complex subunit 6

2

0

High-throughput

0.580

High

792925

GDF5
Growth/differentiation factor 5

2

1

High-throughput

0.574

High

1149246

K1C40
Keratin, type I cytoskeletal 40

1

2

High-throughput

0.573

High

1136594

FHL5
Four and a half LIM domains protein 5

2

2

High-throughput

0.553

High

637956

PSA3
Proteasome subunit alpha type-3

1

0

High-throughput

0.549

High

1223238

EXOC8
Exocyst complex component 8

1

0

High-throughput

0.536

High

422630

GPX1
Glutathione peroxidase 1

1

0

High-throughput

0.513

High

921657

GBB2
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2

1

0

High-throughput

0.513

High

964794

AMPD2
AMP deaminase 2

1

0

High-throughput

0.513

High

974502

ENL
Protein ENL

1

0

High-throughput

0.513

High

1028401

M3K1
Mitogen-activated protein kinase kinase kinase 1

1

3

Small-scale

0.501

High

1109334

KRA63
Keratin-associated protein 6-3

1

0

High-throughput

0.493

High

1252958

IP6K1
Inositol hexakisphosphate kinase 1

1

0

Small-scale

0.480

High

208739

TPPC3
Trafficking protein particle complex subunit 3

1

1

High-throughput

0.479

High

819720

TPC10
Trafficking protein particle complex subunit 10

1

1

High-throughput

0.479

High

1222249

AMOL1
Angiomotin-like protein 1

1

1

High-throughput

0.479

High

1252962

TPPC9
Trafficking protein particle complex subunit 9

1

1

High-throughput

0.479

High

1252965

PDLI7
PDZ and LIM domain protein 7

1

1

High-throughput

0.479

High

1252969

TPC2L
Trafficking protein particle complex subunit 2-like protein

1

2

High-throughput

0.479

High

1252971

TPPC4
Trafficking protein particle complex subunit 4

1

3

High-throughput

0.479

High

1252973

TPPC1
Trafficking protein particle complex subunit 1

1

3

High-throughput

0.479

High

484670

NT2NC
Notch homolog 2 N-terminal-like protein C

1

1

High-throughput

0.470

High

814099

IF1AX
Eukaryotic translation initiation factor 1A, X-chromosomal

1

0

High-throughput

0.458

High

1222779

M21D2
Nucleotidyltransferase MB21D2

1

3

High-throughput

0.437

High

1252968

MIC19
MICOS complex subunit MIC19

1

1

High-throughput

0.417

High

1127078

MTUS2
Microtubule-associated tumor suppressor candidate 2

4

0

High-throughput

0.364

High

1220021

SUGP2
SURP and G-patch domain-containing protein 2

3

0

High-throughput

0.347

High

1252959

C102A
Coiled-coil domain-containing protein 102A

3

0

High-throughput

0.347

High

1252966

CYRIB
CYFIP-related Rac1 interactor B

2

0

High-throughput

0.328

High

67243

CRTP1
Cysteine-rich tail protein 1

2

0

High-throughput

0.316

High

1102081

CB068
UPF0561 protein C2orf68

2

0

High-throughput

0.316

High

1252964

CTDS1
Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1

2

0

High-throughput

0.316

High

1102770

CCD57
Coiled-coil domain-containing protein 57

1

0

High-throughput

0.299

High

1156002

TIGD7
Tigger transposable element-derived protein 7

1

0

High-throughput

0.299

High

1252970

SATB2
DNA-binding protein SATB2

1

0

High-throughput

0.299

High

1161742

KLD10
Kelch domain-containing protein 10

1

0

High-throughput

0.279

Low

1229540

SYCE1
Synaptonemal complex central element protein 1

1

0

High-throughput

0.279

Low

583

NBPFJ
Neuroblastoma breakpoint family member 19

1

0

High-throughput

0.251

Low

1188591

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024