Protein: PKP1
Plakophilin-1 (Band 6 protein) (B6P)

Gene: PKP1
Organism: Homo sapiens
Interactions: 138
UniProt ID: Q13835

Gene Ontology (top 5):
GO:0001533 - cornified envelope
GO:0005521 - lamin binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

970770

DSG1
Desmoglein-1

3

20

Small-scale

0.840

High

1045998

CPLN2
Ciliogenesis and planar polarity effector 2

2

0

High-throughput

0.748

High

236533

CIDEA
Lipid transferase CIDEA

3

1

High-throughput

0.667

High

1045974

ARMC8
Armadillo repeat-containing protein 8

1

7

Small-scale

0.656

High

551698

DESP
Desmoplakin

2

11

Small-scale

0.634

High

1045977

CCD82
Coiled-coil domain-containing protein 82

2

1

High-throughput

0.628

High

1046023

FCF1
rRNA-processing protein FCF1 homolog

2

1

High-throughput

0.628

High

346737

MYC
Myc proto-oncogene protein

2

11

High-throughput

0.611

High

716576

CAH8
Carbonic anhydrase-related protein

2

3

High-throughput

0.611

High

1045960

SGO2
Shugoshin 2

2

1

High-throughput

0.611

High

1045990

TFG
Protein TFG

2

6

High-throughput

0.611

High

1046000

RBM24
RNA-binding protein 24

2

10

High-throughput

0.611

High

1045994

MITOK
Mitochondrial potassium channel

3

2

High-throughput

0.609

High

49759

BICL2
BICD family-like cargo adapter 2

2

14

High-throughput

0.606

High

994858

GOGA2
Golgin subfamily A member 2

2

9

High-throughput

0.606

High

1045983

IKBD
NF-kappa-B inhibitor delta

2

10

High-throughput

0.606

High

1045993

HOOK2
Protein Hook homolog 2

2

13

High-throughput

0.606

High

1045999

CAR10
Caspase recruitment domain-containing protein 10

2

11

High-throughput

0.606

High

443505

VIME
Vimentin

1

8

Small-scale

0.589

High

995963

DSC1
Desmocollin-1

2

20

Small-scale

0.586

High

409065

K2C8
Keratin, type II cytoskeletal 8

1

4

Small-scale

0.586

High

253008

HSF2B
Heat shock factor 2-binding protein

2

0

High-throughput

0.580

High

1046019

FBXL4
F-box/LRR-repeat protein 4

2

1

High-throughput

0.574

High

1046024

KIF3A
Kinesin-like protein KIF3A

2

6

High-throughput

0.574

High

1046017

GT2D1
General transcription factor II-I repeat domain-containing protein 1

1

3

Small-scale

0.573

High

1045966

TENS2
Tensin-2

1

8

High-throughput

0.573

High

359345

K1C14
Keratin, type I cytoskeletal 14

1

8

Small-scale

0.561

High

239983

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

2

High-throughput

0.536

High

281988

ANXA9
Annexin A9

1

2

High-throughput

0.536

High

345429

FOS
Protein c-Fos

1

6

High-throughput

0.536

High

408795

K1C18
Keratin, type I cytoskeletal 18

1

11

Small-scale

0.536

High

565920

AATC
Aspartate aminotransferase, cytoplasmic

1

2

High-throughput

0.536

High

686653

CCR1
C-C chemokine receptor type 1

1

3

High-throughput

0.536

High

882729

STX17
Syntaxin-17

1

2

High-throughput

0.536

High

987764

GABPA
GA-binding protein alpha chain

1

4

High-throughput

0.536

High

1017118

SNF5
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1

1

1

High-throughput

0.536

High

1045963

WIPI1
WD repeat domain phosphoinositide-interacting protein 1

1

6

High-throughput

0.536

High

1045967

JADE1
Protein Jade-1

1

5

High-throughput

0.536

High

1045969

OPN5
Opsin-5

1

6

High-throughput

0.536

High

1045970

CD109
CD109 antigen

1

2

High-throughput

0.536

High

1045971

FOXI2
Forkhead box protein I2

1

7

High-throughput

0.536

High

1045972

ZC3C1
Zinc finger C3HC-type protein 1

1

2

High-throughput

0.536

High

1045981

FNDC5
Fibronectin type III domain-containing protein 5

1

2

High-throughput

0.536

High

1045992

SIA7F
Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6

1

3

High-throughput

0.536

High

1046001

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

1

13

High-throughput

0.536

High

1046002

SRRT
Serrate RNA effector molecule homolog

1

2

High-throughput

0.536

High

1046011

MBNL1
Muscleblind-like protein 1

1

1

High-throughput

0.536

High

1046012

RFOX1
RNA binding protein fox-1 homolog 1

1

10

High-throughput

0.536

High

1046013

GPT2L
G patch domain-containing protein 2-like

1

1

High-throughput

0.536

High

1046018

PHF11
PHD finger protein 11

1

9

High-throughput

0.536

High

1046020

OAZ3
Ornithine decarboxylase antizyme 3

1

2

High-throughput

0.536

High

1046022

SSUH2
Protein SSUH2 homolog

1

2

High-throughput

0.536

High

488711

ARAF
Serine/threonine-protein kinase A-Raf

2

12

High-throughput

0.521

High

296303

UBP1
Ubiquitin carboxyl-terminal hydrolase 1

1

14

High-throughput

0.515

High

183025

P2RX6
P2X purinoceptor 6

1

0

High-throughput

0.513

High

215816

G6PT1
Glucose-6-phosphate exchanger SLC37A4

1

0

High-throughput

0.513

High

921115

RPAB5
DNA-directed RNA polymerases I, II, and III subunit RPABC5

1

0

High-throughput

0.513

High

1045976

SPICE
Spindle and centriole-associated protein 1

1

0

High-throughput

0.513

High

1046014

TEX10
Testis-expressed protein 10

1

0

High-throughput

0.513

High

1046021

PHF8
Histone lysine demethylase PHF8

1

0

High-throughput

0.513

High

1046025

UCHL5
Ubiquitin carboxyl-terminal hydrolase isozyme L5

1

5

Small-scale

0.501

High

1045957

SUZ12
Polycomb protein SUZ12

1

0

High-throughput

0.493

High

303682

OR2A4
Olfactory receptor 2A4

1

2

High-throughput

0.489

High

396468

ALDH2
Aldehyde dehydrogenase, mitochondrial

1

1

High-throughput

0.489

High

813020

CAZA2
F-actin-capping protein subunit alpha-2

1

3

High-throughput

0.489

High

821555

PTSS1
Phosphatidylserine synthase 1

1

2

High-throughput

0.489

High

958673

2ABB
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform

1

4

High-throughput

0.489

High

1045959

CR021
UPF0711 protein C18orf21

1

1

High-throughput

0.489

High

1045973

MICU3
Calcium uptake protein 3, mitochondrial

1

2

High-throughput

0.489

High

1045975

NRSN1
Neurensin-1

1

1

High-throughput

0.489

High

1045987

CPLX3
Complexin-3

1

1

High-throughput

0.489

High

1045989

ZDH19
Palmitoyltransferase ZDHHC19

1

1

High-throughput

0.489

High

1046008

TMT1A
Thiol S-methyltransferase TMT1A

1

1

High-throughput

0.489

High

134031

DDX3X
ATP-dependent RNA helicase DDX3X

1

6

Small-scale

0.479

High

168790

ARC1B
Actin-related protein 2/3 complex subunit 1B

1

8

Small-scale

0.479

High

282646

RNF8
E3 ubiquitin-protein ligase RNF8

1

10

High-throughput

0.479

High

325725

LATS1
Serine/threonine-protein kinase LATS1

1

8

High-throughput

0.479

High

427552

ANXA2
Annexin A2

1

2

High-throughput

0.479

High

428581

INVO
Involucrin

1

6

High-throughput

0.479

High

453347

ROA1
Heterogeneous nuclear ribonucleoprotein A1

1

5

High-throughput

0.479

High

531565

K2C5
Keratin, type II cytoskeletal 5

1

4

Small-scale

0.479

High

580023

K1C15
Keratin, type I cytoskeletal 15

1

8

Small-scale

0.479

High

596273

FILA
Filaggrin

1

7

High-throughput

0.479

High

614035

TBG1
Tubulin gamma-1 chain

1

4

High-throughput

0.479

High

651162

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

6

High-throughput

0.479

High

667959

SPB3
Serpin B3

1

3

High-throughput

0.479

High

683078

CASPE
Caspase-14

1

4

High-throughput

0.479

High

717801

BMI1
Polycomb complex protein BMI-1

1

10

High-throughput

0.479

High

720420

RFA3
Replication protein A 14 kDa subunit

1

6

High-throughput

0.479

High

738752

SPB5
Serpin B5

1

4

High-throughput

0.479

High

779380

CCNF
Cyclin-F

1

10

High-throughput

0.479

High

832442

MCM2
DNA replication licensing factor MCM2

1

15

High-throughput

0.479

High

851323

NEK2
Serine/threonine-protein kinase Nek2

1

6

Small-scale

0.479

High

908512

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

5

High-throughput

0.479

High

961103

HSF1
Heat shock factor protein 1

1

3

High-throughput

0.479

High

993946

TGM3
Protein-glutamine gamma-glutamyltransferase E

1

1

High-throughput

0.479

High

1025738

TADBP
TAR DNA-binding protein 43

1

7

High-throughput

0.479

High

1035709

BIRC3
Baculoviral IAP repeat-containing protein 3

1

4

High-throughput

0.479

High

1045954

DX39B
Spliceosome RNA helicase DDX39B

1

10

High-throughput

0.479

High

1045956

CHD4
Chromodomain-helicase-DNA-binding protein 4

1

12

High-throughput

0.479

High

1045962

FILA2
Filaggrin-2

1

9

High-throughput

0.479

High

1045965

MYOME
Myomegalin

1

18

High-throughput

0.479

High

1045968

PRP8
Pre-mRNA-processing-splicing factor 8

1

1

High-throughput

0.479

High

1045985

LNX1
E3 ubiquitin-protein ligase LNX

1

20

Small-scale

0.479

High

1045991

FBXW7
F-box/WD repeat-containing protein 7

1

19

High-throughput

0.479

High

1045995

SPB12
Serpin B12

1

4

High-throughput

0.479

High

1045996

RANB9
Ran-binding protein 9

1

7

Small-scale

0.479

High

1045997

ANM1
Protein arginine N-methyltransferase 1

1

4

High-throughput

0.479

High

1046003

FACD2
Fanconi anemia group D2 protein

1

3

High-throughput

0.479

High

1046004

ACE2
Angiotensin-converting enzyme 2

1

1

High-throughput

0.479

High

1046007

CCDC8
Coiled-coil domain-containing protein 8

1

5

High-throughput

0.479

High

1046009

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

2

High-throughput

0.479

High

1046010

ANLN
Anillin

1

7

High-throughput

0.479

High

1046016

ZRAN1
Ubiquitin thioesterase ZRANB1

1

15

High-throughput

0.479

High

974556

MECOM
Histone-lysine N-methyltransferase MECOM

1

0

High-throughput

0.458

High

1045955

BLMH
Bleomycin hydrolase

1

0

High-throughput

0.458

High

1045988

POF1B
Protein POF1B

1

0

High-throughput

0.458

High

529089

CFTR
Cystic fibrosis transmembrane conductance regulator

1

5

High-throughput

0.445

High

891136

GBRL2
Gamma-aminobutyric acid receptor-associated protein-like 2

1

7

High-throughput

0.445

High

1045961

ODFP2
Outer dense fiber protein 2

1

10

High-throughput

0.445

High

1045964

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

8

High-throughput

0.445

High

1045982

MSPD2
Motile sperm domain-containing protein 2

1

1

High-throughput

0.445

High

427080

CATD
Cathepsin D

1

1

High-throughput

0.437

High

1046005

DDX24
ATP-dependent RNA helicase DDX24

1

7

High-throughput

0.437

High

1045980

POC5
Centrosomal protein POC5

1

0

Small-scale

0.426

High

1045979

PI4P1
Putative inactive phosphatidylinositol 4-kinase alpha-like protein P1

1

4

High-throughput

0.407

High

1046006

GBRL1
Gamma-aminobutyric acid receptor-associated protein-like 1

1

7

High-throughput

0.407

High

1045984

CEP76
Centrosomal protein of 76 kDa

2

0

High-throughput

0.316

High

217562

NDUS5
NADH dehydrogenase [ubiquinone] iron-sulfur protein 5

1

0

High-throughput

0.279

Low

309584

GOSR1
Golgi SNAP receptor complex member 1

1

0

High-throughput

0.279

Low

708221

ERD22
ER lumen protein-retaining receptor 2

1

0

High-throughput

0.279

Low

1017576

FSTL1
Follistatin-related protein 1

1

0

High-throughput

0.279

Low

1045958

PMVK
Phosphomevalonate kinase

1

0

High-throughput

0.279

Low

1045978

PLD5
Inactive phospholipase D5

1

0

High-throughput

0.279

Low

1045986

CGAT1
Chondroitin sulfate N-acetylgalactosaminyltransferase 1

1

0

High-throughput

0.279

Low

1046015

PEMT
Phosphatidylethanolamine N-methyltransferase

1

0

High-throughput

0.279

Low

100749

APRIO
Alternative prion protein

1

0

High-throughput

0.249

Low

1023373

COASY
Bifunctional coenzyme A synthase

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024