Protein: T2FA
Transcription initiation factor IIF subunit alpha (TFIIF-alpha) (TFIIF large subunit) (Transcription factor G 105 kDa subunit) (P105)

Gene: T2FA, TFG1
Organism: Saccharomyces cerevisiae S288C
Interactions: 68
UniProt ID: P41895

Gene Ontology (top 5):
GO:0001096 - TFIIF-class transcription factor complex binding
GO:0001174 - transcriptional start site selection at RNA polymerase II promoter
GO:0003677 - DNA binding
GO:0005634 - nucleus
GO:0005674 - transcription factor TFIIF complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

836526

T2FB
Transcription initiation factor IIF subunit beta

13

0

Small-scale

0.927

High

402033

RPB1
DNA-directed RNA polymerase II subunit RPB1

9

0

Small-scale

0.919

High

470544

RPB2
DNA-directed RNA polymerase II subunit RPB2

7

0

Small-scale

0.914

High

699960

RPB9
DNA-directed RNA polymerase II subunit RPB9

5

0

High-throughput

0.875

High

763336

TAF14
Transcription initiation factor TFIID subunit 14

13

0

Small-scale

0.726

High

594420

RPB3
DNA-directed RNA polymerase II subunit RPB3

11

0

Small-scale

0.723

High

632173

RPAB1
DNA-directed RNA polymerases I, II, and III subunit RPABC1

5

0

Small-scale

0.676

High

757332

RPB7
DNA-directed RNA polymerase II subunit RPB7

4

0

High-throughput

0.661

High

806933

RPB11
DNA-directed RNA polymerase II subunit RPB11

4

0

Small-scale

0.653

High

836535

FCP1
RNA polymerase II subunit A C-terminal domain phosphatase

3

0

Small-scale

0.636

High

836525

T2FA
Transcription initiation factor IIF subunit alpha

1

0

High-throughput

0.631

High

632264

RPAB2
DNA-directed RNA polymerases I, II, and III subunit RPABC2

3

0

High-throughput

0.628

High

645064

RPAB5
DNA-directed RNA polymerases I, II, and III subunit RPABC5

3

0

High-throughput

0.622

High

632095

RPB4
DNA-directed RNA polymerase II subunit RPB4

3

0

Small-scale

0.613

High

694568

SPT5
Transcription elongation factor SPT5

3

0

High-throughput

0.613

High

740416

MED17
Mediator of RNA polymerase II transcription subunit 17

3

0

Small-scale

0.597

High

707381

TF2B
Transcription initiation factor IIB

2

0

High-throughput

0.559

High

748296

SPT4
Transcription elongation factor SPT4

2

0

High-throughput

0.559

High

364595

CDK1
Cyclin-dependent kinase 1

1

0

High-throughput

0.537

High

441164

KAPA
cAMP-dependent protein kinase type 1

1

1

High-throughput

0.536

High

441376

KAPB
cAMP-dependent protein kinase type 2

1

1

High-throughput

0.536

High

815472

RSP5
E3 ubiquitin-protein ligase RSP5

1

1

High-throughput

0.536

High

651950

ESS1
Peptidyl-prolyl cis-trans isomerase ESS1

1

0

High-throughput

0.513

High

836536

TOM1
E3 ubiquitin-protein ligase TOM1

1

1

High-throughput

0.479

High

435163

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.458

High

557731

SRS2
ATP-dependent DNA helicase SRS2

1

0

High-throughput

0.458

High

632351

RPAB3
DNA-directed RNA polymerases I, II, and III subunit RPABC3

1

0

High-throughput

0.458

High

646438

RAD53
Serine/threonine-protein kinase RAD53

1

0

High-throughput

0.458

High

661172

SPT6
Transcription elongation factor SPT6

1

0

High-throughput

0.458

High

679798

CDC48
Cell division control protein 48

1

0

High-throughput

0.458

High

735025

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

0

High-throughput

0.458

High

739666

SPT16
FACT complex subunit SPT16

1

0

High-throughput

0.458

High

744613

TFB1
General transcription and DNA repair factor IIH subunit TFB1

1

0

High-throughput

0.458

High

781943

KAE1
tRNA N6-adenosine threonylcarbamoyltransferase

1

0

High-throughput

0.458

High

797247

HSL7
Protein arginine N-methyltransferase HSL7

1

0

High-throughput

0.458

High

805036

SDO1L
Restriction of telomere capping protein 3

1

0

Small-scale

0.458

High

823708

RPAB4
DNA-directed RNA polymerases I, II, and III subunit RPABC4

1

0

High-throughput

0.458

High

836527

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

1

0

High-throughput

0.458

High

836528

SET2
Histone-lysine N-methyltransferase, H3 lysine-36 specific

1

0

High-throughput

0.458

High

836531

NAF1
H/ACA ribonucleoprotein complex non-core subunit NAF1

1

0

Small-scale

0.458

High

836532

H3
Histone H3

1

0

High-throughput

0.458

High

836533

MCE1
mRNA-capping enzyme subunit alpha

1

0

High-throughput

0.458

High

836537

MUS81
Crossover junction endonuclease MUS81

1

0

High-throughput

0.458

High

836538

URN1
Pre-mRNA-splicing factor URN1

1

0

High-throughput

0.458

High

836539

CDC73
Cell division control protein 73

1

0

High-throughput

0.458

High

836540

ASR1
Alcohol-sensitive RING finger protein 1

1

0

High-throughput

0.458

High

836542

YL11B
Transposon Ty1-LR1 Gag-Pol polyprotein

1

0

High-throughput

0.458

High

836543

SCC1
Sister chromatid cohesion protein 1

1

0

High-throughput

0.458

High

836544

SMT3
Ubiquitin-like protein SMT3

1

0

High-throughput

0.458

High

745132

YME1
Mitochondrial inner membrane i-AAA protease supercomplex subunit YME1

1

1

High-throughput

0.437

High

381140

H2B1
Histone H2B.1

1

0

High-throughput

0.426

High

781054

T2EA
Transcription initiation factor IIE subunit alpha

1

0

Small-scale

0.426

High

782135

T2EB
Transcription initiation factor IIE subunit beta

1

0

Small-scale

0.426

High

836534

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

0

Small-scale

0.426

High

836541

TFB4
General transcription and DNA repair factor IIH subunit TFB4

1

0

Small-scale

0.426

High

811619

YCFI
Metal resistance protein YCF1

1

0

High-throughput

0.282

High

149820

RS9A
Small ribosomal subunit protein uS4A

1

0

High-throughput

0.249

Low

441970

RS14A
Small ribosomal subunit protein uS11A

1

0

High-throughput

0.249

Low

455116

RS19A
Small ribosomal subunit protein eS19A

1

0

High-throughput

0.249

Low

513067

RS8A
Small ribosomal subunit protein eS8A

1

0

High-throughput

0.249

Low

689517

RS7A
Small ribosomal subunit protein eS7A

1

0

High-throughput

0.249

Low

797751

AIM4
Altered inheritance of mitochondria protein 4

1

0

High-throughput

0.249

Low

802229

RS20
Small ribosomal subunit protein uS10

1

0

High-throughput

0.249

Low

812400

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low

836529

MPS3
Spindle pole body assembly component MPS3

1

0

High-throughput

0.249

Low

836530

GPN1
GPN-loop GTPase 1

1

0

High-throughput

0.249

Low

780614

CAB3
Coenzyme A biosynthesis protein 3

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025