Protein: DHE4
Glutamate dehydrogenase 2, mitochondrial (GDH 2) (EC 1.4.1.3)

Gene: DHE4, GLUD2
Organism: Homo sapiens
Interactions: 35
UniProt ID: P49448

Gene Ontology (top 5):
GO:0004352 - glutamate dehydrogenase (NAD+) activity
GO:0004353 - glutamate dehydrogenase [NAD(P)+] activity
GO:0004354 - glutamate dehydrogenase (NADP+) activity
GO:0005525 - GTP binding
GO:0005739 - mitochondrion

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

359619

DHE3
Glutamate dehydrogenase 1, mitochondrial

5

7

High-throughput

0.916

High

883465

KLH22
Kelch-like protein 22

4

1

High-throughput

0.627

High

883474

SH3G3
Endophilin-A3

2

2

High-throughput

0.521

High

583497

ATF2
Cyclic AMP-dependent transcription factor ATF-2

1

1

High-throughput

0.489

High

883468

RFPLB
Ret finger protein-like 4B

1

1

High-throughput

0.489

High

580930

RAC2
Ras-related C3 botulinum toxin substrate 2

1

5

High-throughput

0.479

High

883459

RAC3
Ras-related C3 botulinum toxin substrate 3

1

5

High-throughput

0.479

High

883460

CDC42
Cell division control protein 42 homolog

1

5

High-throughput

0.479

High

883463

CLPP
ATP-dependent Clp protease proteolytic subunit, mitochondrial

1

1

Small-scale

0.479

High

883469

TM10C
tRNA methyltransferase 10 homolog C

1

0

Small-scale

0.458

High

883470

DYR2
Dihydrofolate reductase 2, mitochondrial

1

0

High-throughput

0.458

High

883457

TERA
Transitional endoplasmic reticulum ATPase

1

3

High-throughput

0.445

High

861063

MAP1B
Microtubule-associated protein 1B

1

1

High-throughput

0.437

High

883456

MCM2
DNA replication licensing factor MCM2

1

1

High-throughput

0.437

High

883462

CUL3
Cullin-3

1

1

High-throughput

0.437

High

883464

CL16A
Protein CLEC16A

1

1

High-throughput

0.437

High

883467

TRI67
Tripartite motif-containing protein 67

1

3

High-throughput

0.437

High

883471

CI072
Guanine nucleotide exchange factor C9orf72

1

1

High-throughput

0.437

High

883472

CRBN
Protein cereblon

1

1

Small-scale

0.437

High

883473

RING2
E3 ubiquitin-protein ligase RING2

1

1

High-throughput

0.437

High

883475

MET14
N(6)-adenosine-methyltransferase non-catalytic subunit METTL14

1

1

High-throughput

0.437

High

883477

TRI36
E3 ubiquitin-protein ligase TRIM36

1

3

High-throughput

0.437

High

883478

HYPK
Huntingtin-interacting protein K

1

1

Small-scale

0.437

High

883479

CE164
Centrosomal protein of 164 kDa

1

2

High-throughput

0.437

High

653193

HEMH
Ferrochelatase, mitochondrial

1

0

High-throughput

0.426

High

883458

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

1

High-throughput

0.407

High

290236

TM1L1
TOM1-like protein 1

1

0

High-throughput

0.282

High

883461

TSN5
Tetraspanin-5

1

0

High-throughput

0.279

Low

883476

MED4
Mediator of RNA polymerase II transcription subunit 4

1

0

High-throughput

0.279

Low

331723

MTMR5
Myotubularin-related protein 5

1

0

High-throughput

0.249

Low

371462

MYC
Myc proto-oncogene protein

1

0

High-throughput

0.249

Low

417317

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

0

High-throughput

0.249

Low

446767

NPM
Nucleophosmin

1

0

High-throughput

0.249

Low

883466

CP135
Centrosomal protein of 135 kDa

1

0

High-throughput

0.249

Low

883480

TRRAP
Transformation/transcription domain-associated protein

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025