Protein: CDK10
Cyclin-dependent kinase 10 (EC 2.7.11.22) (Cell division protein kinase 10) (Serine/threonine-protein kinase PISSLRE)

Gene: CDK10
Organism: Homo sapiens
Interactions: 55
UniProt ID: Q15131

Gene Ontology (top 5):
GO:0000307 - cyclin-dependent protein kinase holoenzyme complex
GO:0004674 - protein serine/threonine kinase activity
GO:0004693 - cyclin-dependent protein serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1143033

CCNQ
Cyclin-Q

2

20

Small-scale

0.825

High

977702

ACTA
Actin, aortic smooth muscle

2

8

High-throughput

0.811

High

1143028

ACTBL
Beta-actin-like protein 2

2

8

High-throughput

0.811

High

468391

HS90B
Heat shock protein HSP 90-beta

2

19

High-throughput

0.802

High

1143026

CDC37
Hsp90 co-chaperone Cdc37

2

6

High-throughput

0.789

High

461495

HS90A
Heat shock protein HSP 90-alpha

1

18

High-throughput

0.691

High

952833

ACTB
Actin, cytoplasmic 1

1

8

High-throughput

0.691

High

1105931

FKBP5
Peptidyl-prolyl cis-trans isomerase FKBP5

1

12

High-throughput

0.691

High

1143043

KPCD2
Serine/threonine-protein kinase D2

1

6

High-throughput

0.691

High

1143045

RALY
RNA-binding protein Raly

1

4

High-throughput

0.691

High

578297

ETS2
Protein C-ets-2

3

1

Small-scale

0.672

High

537194

HSP7C
Heat shock cognate 71 kDa protein

2

9

High-throughput

0.628

High

906970

CCR4
C-C chemokine receptor type 4

1

2

High-throughput

0.625

High

1007026

TCPB
T-complex protein 1 subunit beta

2

16

High-throughput

0.621

High

251584

CCNT1
Cyclin-T1

1

20

High-throughput

0.618

High

355349

CCNE2
G1/S-specific cyclin-E2

1

20

High-throughput

0.618

High

629124

CCNA2
Cyclin-A2

1

20

High-throughput

0.618

High

908298

AFF3
AF4/FMR2 family member 3

1

6

High-throughput

0.618

High

1129077

PLSI
Plastin-1

1

5

High-throughput

0.618

High

1143029

Q6PK50
HSP90AB1 protein

1

19

High-throughput

0.618

High

1143031

CCNJL
Cyclin-J-like protein

1

20

High-throughput

0.618

High

1143035

CABL1
CDK5 and ABL1 enzyme substrate 1

1

8

High-throughput

0.618

High

1143042

CABL2
CDK5 and ABL1 enzyme substrate 2

1

8

High-throughput

0.618

High

731316

STIP1
Stress-induced-phosphoprotein 1

2

5

High-throughput

0.611

High

1109266

PIN1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1

1

3

Small-scale

0.589

High

1143039

TTC14
Tetratricopeptide repeat protein 14

2

15

High-throughput

0.558

High

501996

H2AZ
Histone H2A.Z

1

5

High-throughput

0.536

High

1143036

TCPW
T-complex protein 1 subunit zeta-2

1

16

High-throughput

0.536

High

1036567

SEMG2
Semenogelin-2

1

1

High-throughput

0.515

High

162348

PDCD5
Programmed cell death protein 5

1

0

High-throughput

0.513

High

480144

RU1C
U1 small nuclear ribonucleoprotein C

1

0

High-throughput

0.513

High

1143044

CYBP
Calcyclin-binding protein

1

0

High-throughput

0.513

High

1143025

AINX
Alpha-internexin

1

5

High-throughput

0.489

High

1143046

SGT1
Protein SGT1 homolog

1

5

High-throughput

0.489

High

1143048

RN115
E3 ubiquitin-protein ligase RNF115

1

3

Small-scale

0.481

High

1143047

FBX7
F-box only protein 7

1

0

High-throughput

0.480

High

216005

FIBP
Acidic fibroblast growth factor intracellular-binding protein

1

1

High-throughput

0.479

High

284316

GEMI
Geminin

1

3

High-throughput

0.479

High

596882

MGMT
Methylated-DNA--protein-cysteine methyltransferase

1

2

Small-scale

0.479

High

992185

SKP1
S-phase kinase-associated protein 1

1

5

High-throughput

0.479

High

1118809

TF2H2
General transcription factor IIH subunit 2

1

2

High-throughput

0.479

High

1122879

TFDP2
Transcription factor Dp-2

1

8

High-throughput

0.479

High

1143037

Q96BE0
Heat shock cognate 71 kDa protein

1

10

High-throughput

0.479

High

1143041

AASD1
Alanyl-tRNA editing protein Aarsd1

1

2

High-throughput

0.479

High

1143032

NUDC3
NudC domain-containing protein 3

1

0

High-throughput

0.458

High

1143034

INT1
Integrator complex subunit 1

1

0

High-throughput

0.458

High

1143038

LRAT2
Protein LRATD2

1

0

High-throughput

0.458

High

704968

RBL1
Retinoblastoma-like protein 1

1

11

High-throughput

0.437

High

1040722

ENL
Protein ENL

1

7

High-throughput

0.437

High

1065663

RBL2
Retinoblastoma-like protein 2

1

11

High-throughput

0.437

High

1085153

TMM94
Transmembrane protein 94

1

2

High-throughput

0.437

High

1143030

C2CD5
C2 domain-containing protein 5

1

5

High-throughput

0.437

High

1143040

Q9BPW0
Serine/threonine-protein phosphatase

1

11

High-throughput

0.437

High

1143027

ECM1
Extracellular matrix protein 1

1

0

High-throughput

0.279

Low

292908

RNH2A
Ribonuclease H2 subunit A

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025