Protein: T3HPD
Trans-3-hydroxy-L-proline dehydratase (EC 4.2.1.77) (Trans-L-3-hydroxyproline dehydratase)

Gene: T3HPD, L3HYPDH
Organism: Homo sapiens
Interactions: 38
UniProt ID: Q96EM0

Gene Ontology (top 5):
GO:0016836 - hydro-lyase activity
GO:0050346 - trans-L-3-hydroxyproline dehydratase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1150523

DIXC1
Dixin

3

1

High-throughput

0.609

High

1347591

UHMK1
Serine/threonine-protein kinase Kist

1

2

High-throughput

0.489

High

184648

MK13
Mitogen-activated protein kinase 13

1

1

High-throughput

0.407

High

862689

UTRN
Utrophin

4

0

High-throughput

0.360

High

355352

CCNE2
G1/S-specific cyclin-E2

3

0

High-throughput

0.347

High

1226616

CBPZ
Carboxypeptidase Z

3

0

High-throughput

0.347

High

1242778

RL22L
Ribosomal protein eL22-like

3

0

High-throughput

0.342

High

972514

RS14
Small ribosomal subunit protein uS11

2

0

High-throughput

0.328

High

1389313

IP6K3
Inositol hexakisphosphate kinase 3

2

0

High-throughput

0.328

High

883130

AL7A1
Alpha-aminoadipic semialdehyde dehydrogenase

2

0

High-throughput

0.318

High

1333808

RDH13
Retinol dehydrogenase 13

2

0

High-throughput

0.318

High

1389314

RPC3
DNA-directed RNA polymerase III subunit RPC3

2

0

High-throughput

0.318

High

1389317

KBRS2
NF-kappa-B inhibitor-interacting Ras-like protein 2

2

0

High-throughput

0.318

High

1389319

GSTK1
Glutathione S-transferase kappa 1

2

0

High-throughput

0.318

High

1389320

ACOT9
Acyl-coenzyme A thioesterase 9, mitochondrial

2

0

High-throughput

0.318

High

1389321

KLK5
Kallikrein-5

2

0

High-throughput

0.313

High

1389322

TCAF1
TRPM8 channel-associated factor 1

2

0

High-throughput

0.313

High

608328

EGLN
Endoglin

1

0

High-throughput

0.279

Low

667979

CDK2
Cyclin-dependent kinase 2

1

0

High-throughput

0.279

Low

788742

SRP14
Signal recognition particle 14 kDa protein

1

0

High-throughput

0.279

Low

909131

NEK4
Serine/threonine-protein kinase Nek4

1

0

High-throughput

0.279

Low

1104859

SNTB2
Beta-2-syntrophin

1

0

High-throughput

0.279

Low

1204484

RNS13
Probable inactive ribonuclease-like protein 13

1

0

High-throughput

0.279

Low

1242898

S39A4
Zinc transporter ZIP4

1

0

High-throughput

0.279

Low

1309141

MISP
Mitotic interactor and substrate of PLK1

1

0

High-throughput

0.279

Low

1389318

DD19B
ATP-dependent RNA helicase DDX19B

1

0

High-throughput

0.279

Low

163152

CHK1
Serine/threonine-protein kinase Chk1

1

0

High-throughput

0.249

Low

643250

MUTA
Methylmalonyl-CoA mutase, mitochondrial

1

0

High-throughput

0.249

Low

831225

CCNF
Cyclin-F

1

0

High-throughput

0.249

Low

1255019

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

1389315

THUM3
tRNA

1

0

High-throughput

0.249

Low

1389316

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.249

Low

460924

LDHC
L-lactate dehydrogenase C chain

1

0

High-throughput

0.232

Low

788324

GPX4
Phospholipid hydroperoxide glutathione peroxidase GPX4

1

0

High-throughput

0.232

Low

841068

HELZ
Probable helicase with zinc finger domain

1

0

High-throughput

0.232

Low

1040184

M2OM
Mitochondrial 2-oxoglutarate/malate carrier protein

1

0

High-throughput

0.232

Low

1366801

PGTA
Geranylgeranyl transferase type-2 subunit alpha

1

0

High-throughput

0.232

Low

1389323

NCOR2
Nuclear receptor corepressor 2

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025