Protein: TTBK1
Tau-tubulin kinase 1 (EC 2.7.11.1) (Brain-derived tau kinase)

Gene: TTBK1
Organism: Homo sapiens
Interactions: 26
UniProt ID: Q5TCY1

Gene Ontology (top 5):
GO:0004674 - protein serine/threonine kinase activity
GO:0004713 - protein tyrosine kinase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1216045

TTBK2
Tau-tubulin kinase 2

2

18

High-throughput

0.789

High

1091413

ANK3
Ankyrin-3

1

10

High-throughput

0.691

High

462460

HNRPC
Heterogeneous nuclear ribonucleoproteins C1/C2

1

11

High-throughput

0.665

High

1216044

TTBK1
Tau-tubulin kinase 1

1

16

Small-scale

0.647

High

952202

GBRL2
Gamma-aminobutyric acid receptor-associated protein-like 2

2

6

High-throughput

0.611

High

328043

GBRAP
Gamma-aminobutyric acid receptor-associated protein

1

6

High-throughput

0.536

High

788060

ODO2
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial

1

1

High-throughput

0.536

High

1152098

MARE1
Microtubule-associated protein RP/EB family member 1

1

7

High-throughput

0.536

High

1216048

APBP2
Amyloid protein-binding protein 2

1

5

High-throughput

0.536

High

1216049

GBRL1
Gamma-aminobutyric acid receptor-associated protein-like 1

1

6

High-throughput

0.536

High

1216053

MARE3
Microtubule-associated protein RP/EB family member 3

1

7

High-throughput

0.536

High

1216054

KDM3A
Lysine-specific demethylase 3A

1

4

High-throughput

0.536

High

966441

1433G
14-3-3 protein gamma

1

20

High-throughput

0.515

High

1194743

ACSF3
Malonate--CoA ligase ACSF3, mitochondrial

1

0

High-throughput

0.513

High

1216052

ATG3
Ubiquitin-like-conjugating enzyme ATG3

1

0

High-throughput

0.513

High

529946

TAU
Microtubule-associated protein tau

1

11

Small-scale

0.501

High

339512

ACSL3
Fatty acid CoA ligase Acsl3

1

0

High-throughput

0.493

High

1216051

HEAT1
HEAT repeat-containing protein 1

1

0

High-throughput

0.493

High

985706

RL11
Large ribosomal subunit protein uL5

1

1

Small-scale

0.479

High

1113336

CUL3
Cullin-3

1

11

High-throughput

0.479

High

1115248

CUL4B
Cullin-4B

1

11

High-throughput

0.479

High

1216046

FBXW8
F-box/WD repeat-containing protein 8

1

20

High-throughput

0.479

High

1216050

TXNIP
Thioredoxin-interacting protein

1

12

Small-scale

0.479

High

1216047

NU205
Nuclear pore complex protein Nup205

1

0

High-throughput

0.458

High

1199502

KLH22
Kelch-like protein 22

1

6

High-throughput

0.445

High


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Last updated: 11Aug2025