Protein: DLD1
D-lactate dehydrogenase [cytochrome] 1, mitochondrial (EC 1.1.2.4) (D-lactate ferricytochrome C oxidoreductase) (D-LCR)

Gene: DLD1
Organism: Saccharomyces cerevisiae S288C
Interactions: 66
UniProt ID: P32891

Gene Ontology (top 5):
GO:0004458 - D-lactate dehydrogenase (cytochrome) activity
GO:0005739 - mitochondrion
GO:0005743 - mitochondrial inner membrane
GO:0005758 - mitochondrial intermembrane space
GO:0008720 - D-lactate dehydrogenase (NAD+) activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

746572

MIC60
MICOS complex subunit MIC60

3

0

High-throughput

0.613

High

613549

ADT2
ADP,ATP carrier protein 2

2

0

Small-scale

0.585

High

746584

TOM22
Mitochondrial import receptor subunit TOM22

2

1

High-throughput

0.584

High

579098

HSC82
ATP-dependent molecular chaperone HSC82

2

3

High-throughput

0.571

High

357820

QCR7
Cytochrome b-c1 complex subunit 7, mitochondrial

1

1

High-throughput

0.479

High

360782

COX5A
Cytochrome c oxidase subunit 5A, mitochondrial

1

1

High-throughput

0.479

High

360826

COX5B
Cytochrome c oxidase subunit 5B, mitochondrial

1

1

High-throughput

0.479

High

453129

QCR1
Cytochrome b-c1 complex subunit 1, mitochondrial

1

2

High-throughput

0.479

High

453268

QCR2
Cytochrome b-c1 complex subunit 2, mitochondrial

1

1

High-throughput

0.479

High

510334

HSP77
Import motor subunit, mitochondrial

1

5

High-throughput

0.479

High

594914

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, mitochondrial

1

3

High-throughput

0.479

High

679519

CDC48
Cell division control protein 48

1

4

High-throughput

0.479

High

746573

TCD1
tRNA threonylcarbamoyladenosine dehydratase 1

1

1

High-throughput

0.479

High

746575

PP2C7
Protein phosphatase 2C homolog 7, mitochondrial

1

1

High-throughput

0.479

High

746576

AFG3
Mitochondrial inner membrane m-AAA protease component YTA10

1

1

High-throughput

0.479

High

746579

YTA12
Mitochondrial inner membrane m-AAA protease component YTA12

1

2

High-throughput

0.479

High

746582

PHB1
Prohibitin-1

1

2

High-throughput

0.479

High

746586

PHB2
Prohibitin-2

1

2

High-throughput

0.479

High

746587

MCY1
Putative mitochondrial cysteine synthase

1

1

High-throughput

0.479

High

746596

ATG9
Autophagy-related protein 9

1

2

High-throughput

0.479

High

746597

PDP1
[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial

1

1

High-throughput

0.479

High

357697

CYC1
Cytochrome c isoform 1

1

0

High-throughput

0.458

High

357763

QCR6
Cytochrome b-c1 complex subunit 6, mitochondrial

1

0

High-throughput

0.458

High

360648

COX2
Cytochrome c oxidase subunit 2

1

0

High-throughput

0.458

High

360876

COX6
Cytochrome c oxidase subunit 6, mitochondrial

1

0

High-throughput

0.458

High

382865

RMAR
Small ribosomal subunit protein uS3m

1

0

High-throughput

0.458

High

399811

COX4
Cytochrome c oxidase subunit 4, mitochondrial

1

0

High-throughput

0.458

High

417057

VDAC1
Non-selective voltage-gated ion channel 1

1

0

High-throughput

0.458

High

431994

ATPF
ATP synthase subunit 4, mitochondrial

1

0

High-throughput

0.458

High

465325

UCRI
Cytochrome b-c1 complex subunit Rieske, mitochondrial

1

0

High-throughput

0.458

High

470676

QCR8
Cytochrome b-c1 complex subunit 8, mitochondrial

1

0

High-throughput

0.458

High

482189

ATPO
ATP synthase subunit 5, mitochondrial

1

0

High-throughput

0.458

High

661778

TOM40
Mitochondrial import receptor subunit TOM40

1

0

High-throughput

0.458

High

736222

RM41
Large ribosomal subunit protein uL23m

1

0

High-throughput

0.458

High

737440

ODPB
Pyruvate dehydrogenase E1 component subunit beta, mitochondrial

1

0

High-throughput

0.458

High

745228

COX13
Cytochrome c oxidase subunit 13, mitochondrial

1

0

High-throughput

0.458

High

746569

TIM23
Mitochondrial import inner membrane translocase subunit TIM23

1

0

High-throughput

0.458

High

746577

FMP10
Uncharacterized mitochondrial membrane protein FMP10

1

0

High-throughput

0.458

High

746580

MPM1
Mitochondrial peculiar membrane protein 1

1

0

High-throughput

0.458

High

746589

RCF2
Respiratory supercomplex factor 2, mitochondrial

1

0

High-throughput

0.458

High

746590

ATP23
Mitochondrial inner membrane protease ATP23

1

0

High-throughput

0.458

High

746591

COX12
Cytochrome c oxidase subunit 12, mitochondrial

1

0

High-throughput

0.458

High

746593

ATPK
ATP synthase subunit f, mitochondrial

1

0

High-throughput

0.458

High

746594

ATG33
Autophagy-related protein 33

1

0

High-throughput

0.458

High

364435

CDK1
Cyclin-dependent kinase 1

1

1

High-throughput

0.457

High

394393

EF1A
Elongation factor 1-alpha

1

1

High-throughput

0.445

High

450555

FAS1
Fatty acid synthase subunit beta

1

1

High-throughput

0.445

High

526260

HSP72
Heat shock protein SSA2

1

4

High-throughput

0.445

High

746571

GCN1
eIF-2-alpha kinase activator GCN1

1

1

High-throughput

0.445

High

646355

RAD53
Serine/threonine-protein kinase RAD53

1

2

High-throughput

0.437

High

706612

TF2B
Transcription initiation factor IIB

1

2

High-throughput

0.437

High

735473

IRE1
Serine/threonine-protein kinase/endoribonuclease IRE1

1

1

High-throughput

0.437

High

746570

SMY2
Protein SMY2

1

1

High-throughput

0.437

High

746588

PESC
Pescadillo homolog

1

1

High-throughput

0.437

High

453504

PYR1
Multifunctional protein URA2

1

0

High-throughput

0.426

High

746581

LYS12
Homoisocitrate dehydrogenase, mitochondrial

1

0

High-throughput

0.426

High

364994

KPYK1
Pyruvate kinase 1

1

1

High-throughput

0.407

High

544282

SSB1
Ribosome-associated molecular chaperone SSB1

1

6

High-throughput

0.407

High

746574

SSZ1
Ribosome-associated complex subunit SSZ1

1

3

High-throughput

0.407

High

746578

SSB2
Ribosome-associated molecular chaperone SSB2

1

6

High-throughput

0.407

High

746595

VIP1
Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase

1

1

High-throughput

0.407

High

358165

ADH1
Alcohol dehydrogenase 1

1

0

High-throughput

0.232

Low

684666

RL5
Large ribosomal subunit protein uL18

1

0

High-throughput

0.232

Low

746583

MPG1
Mannose-1-phosphate guanyltransferase

1

0

High-throughput

0.232

Low

746585

RL4B
Large ribosomal subunit protein uL4B

1

0

High-throughput

0.232

Low

746592

RRP5
rRNA biogenesis protein RRP5

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025