Protein: URB1
Nucleolar pre-ribosomal-associated protein 1 (Unhealthy ribosome biogenesis protein 1)

Gene: URB1
Organism: Saccharomyces cerevisiae S288C
Interactions: 144
UniProt ID: P34241

Gene Ontology (top 5):
GO:0000463 - maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000466 - maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0003729 - mRNA binding
GO:0005634 - nucleus
GO:0005730 - nucleolus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

710906

DBP6
ATP-dependent RNA helicase DBP6

7

2

Small-scale

0.748

High

710897

URB2
Nucleolar pre-ribosomal-associated protein 2

9

0

Small-scale

0.717

High

710890

NOP2
25S rRNA

5

1

Small-scale

0.712

High

710932

NOP8
60S ribosome subunit biogenesis protein NOP8

7

0

Small-scale

0.710

High

710941

MAK21
Ribosome biogenesis protein MAK21

5

1

Small-scale

0.704

High

710926

RSA3
Ribosome assembly protein 3

6

0

Small-scale

0.700

High

710945

NOP58
Nucleolar protein 58

5

2

Small-scale

0.699

High

710873

MAK5
ATP-dependent RNA helicase MAK5

4

2

Small-scale

0.691

High

710870

NOP4
Nucleolar protein 4

4

1

Small-scale

0.678

High

710878

SSF1
Ribosome biogenesis protein SSF1

5

0

High-throughput

0.676

High

710864

URB1
Nucleolar pre-ribosomal-associated protein 1

4

0

High-throughput

0.657

High

710922

ERB1
Ribosome biogenesis protein ERB1

3

0

Small-scale

0.642

High

710869

DBP7
ATP-dependent RNA helicase DBP7

3

3

Small-scale

0.640

High

691362

NHP2
H/ACA ribonucleoprotein complex subunit NHP2

3

0

Small-scale

0.616

High

710901

PRP43
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP43

2

2

Small-scale

0.611

High

501203

MAK16
Protein MAK16

2

0

High-throughput

0.607

High

490812

HSP71
Heat shock protein SSA1

2

1

High-throughput

0.601

High

638702

SPB4
ATP-dependent rRNA helicase SPB4

2

3

High-throughput

0.584

High

644992

RL16A
Large ribosomal subunit protein uL13A

2

1

Small-scale

0.584

High

710905

YG5X
Putative methyltransferase YGR283C

2

1

High-throughput

0.584

High

710917

HAS1
ATP-dependent RNA helicase HAS1

2

3

Small-scale

0.584

High

710927

DBP9
ATP-dependent RNA helicase DBP9

2

1

Small-scale

0.584

High

710943

NOP56
Nucleolar protein 56

2

2

Small-scale

0.584

High

710920

PUF6
Pumilio homology domain family member 6

2

0

Small-scale

0.576

High

655830

GAR1
H/ACA ribonucleoprotein complex subunit GAR1

2

0

High-throughput

0.563

High

704310

CBF5
H/ACA ribonucleoprotein complex subunit CBF5

2

0

Small-scale

0.559

High

710874

ENP1
Essential nuclear protein 1

2

0

High-throughput

0.559

High

710877

CIC1
Proteasome-interacting protein CIC1

2

0

Small-scale

0.559

High

710879

UTP9
U3 small nucleolar RNA-associated protein 9

2

0

Small-scale

0.559

High

710885

NOC2
Nucleolar complex protein 2

2

0

Small-scale

0.559

High

710895

UTP10
U3 small nucleolar RNA-associated protein 10

2

0

High-throughput

0.559

High

710939

RRP6
Exosome complex exonuclease RRP6

2

0

High-throughput

0.559

High

710924

RRP5
rRNA biogenesis protein RRP5

2

0

Small-scale

0.547

High

339561

CDK1
Cyclin-dependent kinase 1

2

0

High-throughput

0.541

High

534937

RL3
Large ribosomal subunit protein uL3

2

1

Small-scale

0.533

High

510817

SSB1
Ribosome-associated molecular chaperone SSB1

1

0

High-throughput

0.513

High

566159

EST1
Telomere elongation protein EST1

1

0

High-throughput

0.513

High

675938

XPO1
Exportin-1

1

0

High-throughput

0.513

High

710915

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

0

High-throughput

0.513

High

710931

NOP6
Nucleolar protein 6

1

0

High-throughput

0.513

High

710934

DIA2
Protein DIA2

1

0

High-throughput

0.513

High

635107

YCQ6
Uncharacterized protein YCR016W

1

0

High-throughput

0.493

High

416216

SIR2
NAD-dependent histone deacetylase SIR2

1

1

High-throughput

0.479

High

549369

FBRL
rRNA 2'-O-methyltransferase fibrillarin

1

1

Small-scale

0.479

High

648360

NSR1
Nuclear localization sequence-binding protein

1

1

Small-scale

0.479

High

680595

HS104
Heat shock protein 104

1

1

High-throughput

0.479

High

699662

DRS1
ATP-dependent RNA helicase DRS1

1

1

Small-scale

0.479

High

703025

MRT4
Ribosome assembly factor MRT4

1

2

Small-scale

0.479

High

710865

RRP1
Ribosomal RNA-processing protein 1

1

1

Small-scale

0.479

High

710886

NUG1
Nuclear GTP-binding protein NUG1

1

1

Small-scale

0.479

High

710887

RIO2
Serine/threonine-protein kinase RIO2

1

1

High-throughput

0.479

High

710893

EMW1
Essential for maintenance of the cell wall protein 1

1

1

High-throughput

0.479

High

710900

VID30
Vacuolar import and degradation protein 30

1

1

High-throughput

0.479

High

710907

NOG2
Nucleolar GTP-binding protein 2

1

1

High-throughput

0.479

High

710911

NOP15
Ribosome biogenesis protein 15

1

1

Small-scale

0.479

High

710913

H3
Histone H3

1

1

High-throughput

0.479

High

710916

MLP1
Protein MLP1

1

1

High-throughput

0.479

High

710919

DHR1
Probable ATP-dependent RNA helicase DHR1

1

1

High-throughput

0.479

High

710923

YM91
Putative methyltransferase YMR310C

1

1

High-throughput

0.479

High

710928

NOC4
Nucleolar complex protein 4

1

1

High-throughput

0.479

High

710935

NCBP2
Nuclear cap-binding protein subunit 2

1

1

High-throughput

0.479

High

710942

RIO1
Serine/threonine-protein kinase RIO1

1

1

High-throughput

0.479

High

357653

RL28
Large ribosomal subunit protein uL15

1

0

Small-scale

0.458

High

376717

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

1

0

Small-scale

0.458

High

392380

H2A2
Histone H2A.2

1

0

High-throughput

0.458

High

406941

RS3
Small ribosomal subunit protein uS3

1

0

Small-scale

0.458

High

407835

RS13
Small ribosomal subunit protein uS15

1

0

Small-scale

0.458

High

447176

IF2B
Eukaryotic translation initiation factor 2 subunit beta

1

0

Small-scale

0.458

High

457011

SWI6
Regulatory protein SWI6

1

0

High-throughput

0.458

High

478662

IPB2
Protease B inhibitor 2

1

0

High-throughput

0.458

High

557986

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

0

Small-scale

0.458

High

593519

DBP3
ATP-dependent RNA helicase DBP3

1

0

Small-scale

0.458

High

627898

SIS1
Protein SIS1

1

0

Small-scale

0.458

High

630176

RRP43
Exosome complex component RRP43

1

0

High-throughput

0.458

High

631784

RS2
Small ribosomal subunit protein uS5

1

0

Small-scale

0.458

High

634120

SRO9
RNA-binding protein SRO9

1

0

Small-scale

0.458

High

634391

SPB1
27S pre-rRNA

1

0

Small-scale

0.458

High

636582

CDC48
Cell division control protein 48

1

0

Small-scale

0.458

High

640899

RL5
Large ribosomal subunit protein uL18

1

0

Small-scale

0.458

High

661836

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

688186

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

0

High-throughput

0.458

High

689168

PSA5
Proteasome subunit alpha type-5

1

0

Small-scale

0.458

High

710866

MPE1
Protein MPE1

1

0

High-throughput

0.458

High

710867

EBP2
rRNA-processing protein EBP2

1

0

Small-scale

0.458

High

710875

RS20
Small ribosomal subunit protein uS10

1

0

Small-scale

0.458

High

710876

RPN1
26S proteasome regulatory subunit RPN1

1

0

Small-scale

0.458

High

710882

FKBP3
Peptidyl-prolyl cis-trans isomerase

1

0

Small-scale

0.458

High

710888

ULP2
Ubiquitin-like-specific protease 2

1

0

High-throughput

0.458

High

710889

RLP7
Ribosome biogenesis protein RLP7

1

0

High-throughput

0.458

High

710892

T2FB
Transcription initiation factor IIF subunit beta

1

0

High-throughput

0.458

High

710894

KRI1
Protein KRI1

1

0

Small-scale

0.458

High

710899

NOL10
Ribosome biogenesis protein ENP2

1

0

Small-scale

0.458

High

710902

EIF2A
Eukaryotic translation initiation factor 2A

1

0

High-throughput

0.458

High

710903

PESC
Pescadillo homolog

1

0

Small-scale

0.458

High

710904

PXR1
Protein PXR1

1

0

Small-scale

0.458

High

710910

NAT10
RNA cytidine acetyltransferase

1

0

Small-scale

0.458

High

710912

APJ1
J domain-containing protein APJ1

1

0

High-throughput

0.458

High

710918

RRP17
Ribosomal RNA-processing protein 17

1

0

High-throughput

0.458

High

710921

UTP14
U3 small nucleolar RNA-associated protein 14

1

0

High-throughput

0.458

High

710925

HRQ1
ATP-dependent helicase HRQ1

1

0

Small-scale

0.458

High

710933

SGO1
Shugoshin

1

0

High-throughput

0.458

High

710936

NIP7
60S ribosome subunit biogenesis protein NIP7

1

0

Small-scale

0.458

High

710937

YL11B
Transposon Ty1-LR1 Gag-Pol polyprotein

1

0

High-throughput

0.458

High

710944

RUVB2
RuvB-like protein 2

1

0

High-throughput

0.458

High

493608

HSP72
Heat shock protein SSA2

1

1

High-throughput

0.445

High

694419

HSP7F
Heat shock protein homolog SSE1

1

2

High-throughput

0.445

High

399403

RLA0
Large ribosomal subunit protein uL10

1

2

Small-scale

0.437

High

481136

RL1A
Large ribosomal subunit protein uL1A

1

2

High-throughput

0.437

High

541867

NSP1
Nucleoporin NSP1

1

1

Small-scale

0.437

High

589424

PRP2
Pre-mRNA-splicing factor ATP-dependent RNA helicase-like protein PRP2

1

2

High-throughput

0.437

High

691620

NUP2
Nucleoporin NUP2

1

1

Small-scale

0.437

High

710914

NUM1
Nuclear migration protein NUM1

1

1

High-throughput

0.437

High

710929

IMH1
Golgin IMH1

1

1

High-throughput

0.437

High

710880

2A5D
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform

1

0

High-throughput

0.426

High

710908

LTO1
Protein LTO1

1

0

High-throughput

0.426

High

541668

SEC63
Protein translocation protein SEC63

1

1

High-throughput

0.407

High

705009

HSP78
Heat shock protein 78, mitochondrial

1

1

High-throughput

0.407

High

367926

EF1A
Elongation factor 1-alpha

2

0

Small-scale

0.298

High

383057

RL25
Large ribosomal subunit protein uL23

1

0

Small-scale

0.249

Low

399739

RLA1
Large ribosomal subunit protein P1A

1

0

High-throughput

0.249

Low

405161

RL17A
Large ribosomal subunit protein uL22A

1

0

High-throughput

0.249

Low

470972

RS22A
Small ribosomal subunit protein uS8A

1

0

Small-scale

0.249

Low

471761

RL27A
Large ribosomal subunit protein eL27A

1

0

Small-scale

0.249

Low

524250

CAF20
Cap-associated protein CAF20

1

0

High-throughput

0.249

Low

534728

RL30
Large ribosomal subunit protein eL30

1

0

Small-scale

0.249

Low

560941

EF3A
Elongation factor 3A

1

0

Small-scale

0.249

Low

687341

EF2
Elongation factor 2

1

0

Small-scale

0.249

Low

700828

SMY2
Protein SMY2

1

0

High-throughput

0.249

Low

701362

SC61A
Protein transport protein SEC61

1

0

High-throughput

0.249

Low

710868

MIC60
MICOS complex subunit MIC60

1

0

High-throughput

0.249

Low

710871

RL32
Large ribosomal subunit protein eL32

1

0

Small-scale

0.249

Low

710872

SYG
Glycine--tRNA ligase 1, mitochondrial

1

0

High-throughput

0.249

Low

710881

CH10
10 kDa heat shock protein, mitochondrial

1

0

High-throughput

0.249

Low

710883

SSN2
Mediator of RNA polymerase II transcription subunit 13

1

0

Small-scale

0.249

Low

710884

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low

710891

RL10
Large ribosomal subunit protein uL16

1

0

Small-scale

0.249

Low

710898

GPN1
GPN-loop GTPase 1

1

0

Small-scale

0.249

Low

710930

VAM6
Vacuolar morphogenesis protein 6

1

0

High-throughput

0.249

Low

710938

ATG9
Autophagy-related protein 9

1

0

High-throughput

0.249

Low

710940

GET3
ATPase GET3

1

0

High-throughput

0.249

Low

543498

HSC82
ATP-dependent molecular chaperone HSC82

1

0

High-throughput

0.232

Low

710896

PFD1
Prefoldin subunit 1

1

0

High-throughput

0.232

Low

710909

PFD4
Prefoldin subunit 4

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024