Protein: COX1
Cytochrome c oxidase subunit 1 (EC 7.1.1.9) (Cytochrome c oxidase polypeptide I)

Gene: COX1
Organism: Saccharomyces cerevisiae S288C
Interactions: 53
UniProt ID: P00401

Gene Ontology (top 5):
GO:0004129 - cytochrome-c oxidase activity
GO:0005739 - mitochondrion
GO:0005743 - mitochondrial inner membrane
GO:0006123 - mitochondrial electron transport, cytochrome c to oxygen
GO:0009060 - aerobic respiration

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

360302

COX2
Cytochrome c oxidase subunit 2

9

1

Small-scale

0.961

High

360309

COX4
Cytochrome c oxidase subunit 4, mitochondrial

7

4

Small-scale

0.953

High

360303

COX3
Cytochrome c oxidase subunit 3

6

0

Small-scale

0.883

High

360310

COX8
Cytochrome c oxidase subunit 8, mitochondrial

3

0

Small-scale

0.775

High

360304

COX5A
Cytochrome c oxidase subunit 5A, mitochondrial

2

1

Small-scale

0.754

High

360327

COX13
Cytochrome c oxidase subunit 13, mitochondrial

2

2

Small-scale

0.754

High

360320

COX7
Cytochrome c oxidase subunit 7, mitochondrial

2

0

Small-scale

0.728

High

360314

QCR1
Cytochrome b-c1 complex subunit 1, mitochondrial

6

1

Small-scale

0.721

High

360324

MSS51
Protein MSS51, mitochondrial

10

0

Small-scale

0.718

High

360346

RCF1
Respiratory supercomplex factor 1, mitochondrial

7

0

Small-scale

0.705

High

360306

COX6
Cytochrome c oxidase subunit 6, mitochondrial

5

1

Small-scale

0.699

High

360353

COA3
Cytochrome c oxidase assembly factor 3, mitochondrial

6

0

Small-scale

0.690

High

360333

COX14
Cytochrome c oxidase assembly protein COX14

4

0

Small-scale

0.657

High

360336

COA1
Cytochrome c oxidase assembly factor 1

4

0

Small-scale

0.653

High

360342

SHY1
Cytochrome oxidase assembly protein SHY1

3

0

Small-scale

0.628

High

360305

COX5B
Cytochrome c oxidase subunit 5B, mitochondrial

1

1

High-throughput

0.618

High

360343

RCF2
Respiratory supercomplex factor 2, mitochondrial

3

0

Small-scale

0.613

High

360345

COX12
Cytochrome c oxidase subunit 12, mitochondrial

1

0

High-throughput

0.586

High

360329

MIC60
MICOS complex subunit MIC60

2

5

High-throughput

0.584

High

360308

RMAR
Small ribosomal subunit protein uS3m

2

0

Small-scale

0.559

High

360328

TIM23
Mitochondrial import inner membrane translocase subunit TIM23

2

0

Small-scale

0.559

High

360347

COX20
Cytochrome c oxidase assembly protein COX20, mitochondrial

2

0

Small-scale

0.559

High

360340

COX16
Cytochrome c oxidase assembly protein COX16, mitochondrial

1

0

Small-scale

0.513

High

360318

HSP77
Import motor subunit, mitochondrial

1

2

High-throughput

0.479

High

360331

ATPG
ATP synthase subunit gamma, mitochondrial

1

1

High-throughput

0.479

High

357869

CYB
Cytochrome b

1

0

Small-scale

0.458

High

360307

ATP6
ATP synthase subunit a

1

0

Small-scale

0.458

High

360312

CY1
Cytochrome c1, heme protein, mitochondrial

1

0

High-throughput

0.458

High

360313

COX9
Cytochrome c oxidase subunit 9, mitochondrial

1

0

Small-scale

0.458

High

360316

UCRI
Cytochrome b-c1 complex subunit Rieske, mitochondrial

1

0

High-throughput

0.458

High

360317

QCR8
Cytochrome b-c1 complex subunit 8, mitochondrial

1

0

High-throughput

0.458

High

360321

ADT2
ADP,ATP carrier protein 2

1

0

Small-scale

0.458

High

360322

COX10
Protoheme IX farnesyltransferase, mitochondrial

1

0

Small-scale

0.458

High

360323

NFS1
Cysteine desulfurase, mitochondrial

1

0

Small-scale

0.458

High

360325

ACPM
Acyl carrier protein, mitochondrial

1

0

Small-scale

0.458

High

360330

QCR10
Cytochrome b-c1 complex subunit 10, mitochondrial

1

0

Small-scale

0.458

High

360332

CH10
10 kDa heat shock protein, mitochondrial

1

0

Small-scale

0.458

High

360334

OXA1
Mitochondrial inner membrane protein OXA1

1

0

Small-scale

0.458

High

360335

FMP10
Uncharacterized mitochondrial membrane protein FMP10

1

0

High-throughput

0.458

High

360337

INA22
Inner membrane assembly complex subunit 22

1

0

High-throughput

0.458

High

360338

TIM16
Mitochondrial import inner membrane translocase subunit TIM16

1

0

Small-scale

0.458

High

360339

RMD8
Sporulation protein RMD8

1

0

High-throughput

0.458

High

360341

TIM21
Mitochondrial import inner membrane translocase subunit TIM21

1

0

Small-scale

0.458

High

360344

ATP23
Mitochondrial inner membrane protease ATP23

1

0

High-throughput

0.458

High

360348

TIM14
Mitochondrial import inner membrane translocase subunit TIM14

1

0

Small-scale

0.458

High

360349

YD157
Uncharacterized protein YDL157C, mitochondrial

1

0

Small-scale

0.458

High

360351

COX26
Cytochrome c oxidase subunit 26, mitochondrial

1

0

Small-scale

0.458

High

360315

QCR2
Cytochrome b-c1 complex subunit 2, mitochondrial

1

1

Small-scale

0.445

High

360311

CDC31
Cell division control protein 31

1

0

Small-scale

0.249

Low

360319

RL19B
Large ribosomal subunit protein eL19

1

0

High-throughput

0.249

Low

360326

PUB1
Nuclear and cytoplasmic polyadenylated RNA-binding protein PUB1

1

0

High-throughput

0.249

Low

360350

RL13A
Large ribosomal subunit protein eL13A

1

0

High-throughput

0.249

Low

360352

YB255
Uncharacterized protein YBR255C-A

1

0

Small-scale

0.249

Low


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Last updated: 11Aug2025