Protein: DNLI4
DNA ligase 4 (EC 6.5.1.1) (DNA ligase II) (DNA ligase IV) (Polydeoxyribonucleotide synthase [ATP] 4)

Gene: DNLI4, DNL4
Organism: Saccharomyces cerevisiae S288C
Interactions: 29
UniProt ID: Q08387

Gene Ontology (top 5):
GO:0003677 - DNA binding
GO:0003910 - DNA ligase (ATP) activity
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0006297 - nucleotide-excision repair, DNA gap filling

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

917755

XRCC4
Non-homologous end-joining factor LIF1

14

0

Small-scale

0.730

High

919026

PESC
Pescadillo homolog

1

1

High-throughput

0.691

High

1046629

KU80
ATP-dependent DNA helicase II subunit 2

1

6

Small-scale

0.621

High

1040255

GDE1
Glycerophosphocholine phosphodiesterase GDE1

1

1

High-throughput

0.618

High

393451

HSP82
ATP-dependent molecular chaperone HSP82

2

2

High-throughput

0.584

High

419523

H2A1
Histone H2A.1

1

4

High-throughput

0.536

High

635993

ODO1
2-oxoglutarate dehydrogenase, mitochondrial

1

1

High-throughput

0.536

High

1063913

YTM1
Ribosome biogenesis protein YTM1

1

1

High-throughput

0.536

High

622398

ACON
Aconitate hydratase, mitochondrial

1

0

High-throughput

0.513

High

830199

NOP2
25S rRNA

1

0

High-throughput

0.513

High

917573

NSA1
Ribosome biogenesis protein NSA1

1

0

High-throughput

0.513

High

924861

NOP15
Ribosome biogenesis protein 15

1

0

High-throughput

0.513

High

1063915

IF6
Eukaryotic translation initiation factor 6

1

0

High-throughput

0.513

High

386888

TBB
Tubulin beta chain

1

2

High-throughput

0.500

High

801941

KSP1
Serine/threonine-protein kinase KSP1

1

1

High-throughput

0.500

High

1063914

RUVB2
RuvB-like protein 2

1

2

High-throughput

0.500

High

745538

MRE11
Double-strand break repair protein MRE11

1

1

Small-scale

0.481

High

626906

HSP60
Heat shock protein 60, mitochondrial

1

0

High-throughput

0.479

High

677896

DPO4
DNA polymerase IV

1

2

Small-scale

0.479

High

1053918

NHEJ1
Non-homologous end-joining protein 1

1

0

Small-scale

0.458

High

484801

DLDH
Dihydrolipoyl dehydrogenase, mitochondrial

1

1

High-throughput

0.457

High

676421

MAS5
Mitochondrial protein import protein MAS5

1

1

High-throughput

0.445

High

819988

SSB2
Ribosome-associated molecular chaperone SSB2

1

2

High-throughput

0.445

High

739799

SPT16
FACT complex subunit SPT16

1

1

High-throughput

0.437

High

534155

MAK16
Protein MAK16

1

0

High-throughput

0.279

Low

782472

RPF2
Ribosome biogenesis protein RPF2

1

0

High-throughput

0.279

Low

803956

CIC1
Proteasome-interacting protein CIC1

1

0

High-throughput

0.279

Low

917346

RRT6
Regulator of rDNA transcription protein 6

1

0

High-throughput

0.279

Low

1044538

RKM2
Ribosomal lysine N-methyltransferase 2

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025